N,N-dimethyltryptamine (DMT) is neither formed nor retained in serotonin terminals in the rat brain.
Palner M; Kolesnik E; Baun C; Poetzsch SN; Cumming P · 2026 · Neuropharmacology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Mammalian brain may contain an endogenous pool of the psychedelic substance N,N-dimethyltryptamine (DMT), which may act as a co-transmitter with serotonin (5-HT). We tested the joint hypotheses that endogenous DMT would accumulate in rat…
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Metadata source: Europe PMC · DOI 10.1016/j.neuropharm.2026.110874