e-ISSN: Pending

Browse the failure-mode index

21,277 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Failed Experiment ReportMedicine

Pre-post implementation study of a medication-focused order set for management of acute agitation in a pediatric emergency department.

Mills KP, Kemper M, Hoganson GM et al. · 2026 · American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists

Purpose To assess changes in prescribing practice after implementation of a medication-focused order set for acute agitation management in a pediatric emergency department (ED). Methods Patients 5 to 18 years of age who presented to the…

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Failed Experiment ReportMedicine

Field evaluation in the Eastern United States of a biological control Blossom Protect for fire blight suppression efficacy, potential to cause fruit russeting, and compatibility with fungicides.

Zeng Q, Cox K, Jung J et al. · 2026 · Plant disease

Fire blight is a destructive disease of apple and pear, and its severity is intensified under humid conditions. Biological controls are important components of the integrated management of plant diseases; however, field trials in the…

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Negative / Null Result ReportMedicine

Tolerability and effectiveness of definitive chemoradiotherapy in locally advanced lung cancer patients with combined pulmonary fibrosis and emphysema.

Fujimoto K, Kogo M, Kobayashi H et al. · 2026 · Cancer treatment and research communications

Background This study evaluated the efficacy and safety of definitive chemoradiotherapy (CRT) for lung cancer in patients with combined pulmonary fibrosis and emphysema (CPFE), focusing on radiation pneumonitis (RP). Materials and methods…

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Negative / Null Result ReportMedicine

DNAemia Thresholds to Discontinue Antivirals in Preemptive Management for Cytomegalovirus Seropositive Recipients After Kidney Transplantation.

Miehrig AH, Foresto RD, Tedesco-Silva H et al. · 2026 · Transplantation

Background Treatment of cytomegalovirus (CMV) after kidney transplantation aims to achieve cessation of viral replication; however, the use of highly sensitive DNA assays creates uncertainty regarding the optimal DNAemia threshold for…

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Negative / Null Result ReportMedicine

Patient factors outweigh procedure extent in infection risk after cervical disc arthroplasty.

Mastrokostas PG, Said M, Mastrokostas LE et al. · 2026 · European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society

Purpose To determine the 90-day incidence of surgical site infection (SSI) after cervical disc arthroplasty (CDA), compare single versus multilevel procedures, and identify independent predictors of SSI. Methods We identified adult…

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Negative / Null Result ReportMedicine

Adrenocorticotropin hormone regulates sphingosine-1-phosphate synthesis via cortisol in bovine adrenocortical cells.

Medina-Moctezuma ZB, Guzmán-Sánchez A, González-Aretia D et al. · 2026 · Biochemical and biophysical research communications

Follicle-stimulating hormone (FSH) and luteinizing hormone (LH) stimulate the synthesis of sphingosine-1 phosphate (S1P) in Gs-coupled receptors dependent manner, enabling S1P to mediate specific bioactivities of FSH and LH. Because…

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Negative / Null Result Report

0.1% ropivacaine combined with a lower sufentanil concentration for epidural analgesia does not increase breakthrough pain in the latent phase of labor: a double-blind, randomized, controlled, non-inferiority trial

Zhang X, Shen T, Ye S et al. · 2026 · Preprint

Objective: : To investigate the effect of 0.1% ropivacaine with a lower concentration sufentanil for epidural analgesia during the latent phase of labor. Design: : Double-blind, randomized, controlled, non-inferiority trial. Setting: : A…

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Negative / Null Result ReportMedicine

Do congenital heart diseases or chromosomal anomalies influence the surgical outcomes of esophagocoloplasty in esophageal atresia patients?

Tannuri ACA, Abe Takahasi BN, de Almeida Estrambk G et al. · 2026 · Journal of pediatric surgery

Background Esophageal atresia (EA) is frequently associated with congenital heart disease (CHD) and chromosomal anomalies, mainly Down syndrome (DS). While these conditions affect outcomes following primary repair, their specific impact on…

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Negative / Null Result ReportMedicine

Application of quinoa oil emulsions in fresh goat cheese: effects on lipid profile, technological properties and microstructure.

Muñoz-Tebar N, Lucas-González R, Muñoz-Bas C et al. · 2026 · Food chemistry

This study investigates the use of quinoa oil emulsion as a novel plant-based ingredient to improve the nutritional quality of fresh goat cheese. Quinoa oil emulsions (3 and 6 g/L) were characterized and incorporated in fresh cheese. The…

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Negative / Null Result ReportMedicine

GnRH Administration Increases Synchronisation of Ovulation in Mares.

Cui B, Liu Y, Wu X et al. · 2026 · Reproduction in domestic animals = Zuchthygiene

The objective of this study was to evaluate the effects of exogenous GnRH administration at the beginning of estrus synchronisation in mares during the spring transitional period. Estrus was synchronised using a progesterone releasing…

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Negative / Null Result ReportMedicine

Physiologic, Psychological, Nutritional, and Rest-Activity Observations During 120 Days of Low-Tech Off-Grid Living in the Baja California Desert: A 2-Participant Field Case Study.

Mauvieux B, Montardy Q, Remilly M et al. · 2026 · Wilderness & environmental medicine

Off-grid low-tech living is increasingly proposed for arid environments, yet longitudinal field data documenting health, nutrition, and rest-activity organization under real-world conditions remain scarce. Our objective was to describe…

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Negative / Null Result ReportMedicine

A description of self-selected treatments and self-reported improvement following treatment among post-9/11 veterans experiencing disruptive dizziness following a comprehensive traumatic brain injury evaluation.

Cheever K, Kalvesmaki A, Swan AA et al. · 2026 · Brain injury

Background This study aimed to explore what treatments were sought by post-9/11 Veterans with and without a formal diagnosis related to their long-term dizziness following completion of a Comprehensive Traumatic Brain Injury Evaluation…

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Negative / Null Result Report

Recovery of a WWTP fertilizer added with plant growth promoting bacteria (PGPB). Relationship with antibiotic resistance in the "One Health" environment with an oak species: Quercus ilex

Fernández-Pastrana VM, González-Reguero D, Robas-Mora M et al. · 2026 · Preprint

Abstract Soil degradation is a critical problem in Spain, aggravated by intensive agricultural practices, urbanisation and natural phenomena such as forest fires. This study addresses soil regeneration through the valorisation of waste…

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