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WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Weyer M, Hahnefeld L, Franck L et al. · 2026 · Preprint
Progranulin (PGRN) is a neurotrophic and anti-inflammatory factor produced mainly by neurons and microglia in the central nervous system. Progranulin haploinsufficiency causes frontotemporal dementia (FTD). In a previous study we showed…
View details →Hadichgeni S, Shariatpanahi SP, Goliaei B et al. · 2026 · Preprint
Extremely low-frequency pulsed electromagnetic fields (ELF-PEMFs) have been proposed to modulate intracellular signaling in cancer cells, however, the primary mediators and their temporal sequence remain incompletely understood. In this…
View details →Jamnick NA, Livingston PD, Gammon CJ et al. · 2026 · Frontiers in medicine
Background Cancer cachexia is a multifactorial metabolic syndrome marked by progressive skeletal muscle loss, reduced function, and increased mortality. Mitochondrial dysfunction is a key driver of this phenotype. MOTS-c, a…
View details →Coelho JA, Gomes KS, Cerchiaro G · 2026 · International journal of molecular sciences
Endometriosis is associated with oxidative stress and debilitating symptoms, yet its pathophysiology remains incompletely understood, and current treatments are still limited. In this study, oxidative stress responses were compared in 2D…
View details →Pottorf TS, Lane EL, Haley-Johnson Z et al. · 2026 · The Journal of neuroscience : the official journal of the Society for Neuroscience
Spinal cord ventral horn microglia proliferate after nerve injuries and migrate toward cell bodies of injured motoneurons (MNs) enwrapping them. The significance of this microglia reaction has remained unclear. Moreover, some injured MNs…
View details →Scioli MV, Sosa E, Barale J et al. · 2026 · Veterinary immunology and immunopathology
Bovine genital campylobacteriosis (BGC) remains a major cause of reproductive failure in beef cattle systems. This study evaluated the persistence of Campylobacter fetus subsp. venerealis (Cfv) and associated lesions in the reproductive…
View details →Ormes JA, Smrcka AV, Jutkiewicz EM · 2026 · Molecular pharmacology
The clinical utility of μ-opioid receptor (MOR) agonists is limited by side effects and tolerance. G protein βγ subunits (Gβγ) are critical mediators of MOR signaling that not only drive anticonception but also regulate phospholipase C and…
View details →Sigaard JVA, Spindler H, Joensen EDR et al. · 2026 · Journal of palliative medicine
Background An estimated 4.4 million people in Europe require palliative care annually, a number expected to rise with population aging. Telepalliative care (TPC) has been practiced in various settings over the past two decades. The Telepal…
View details →AhmadQaderi F, Pazouki A, Pishgahroudsari M et al. · 2026 · Obesity surgery
BACKGROUND: Metabolic-bariatric surgery (MBS) is recognized as the most effective long-term intervention for obesity and its associated conditions, including type 2 diabetes mellitus (T2DM) One-anastomosis gastric bypass (OAGB), the third…
View details →Del-Ángel-Monroy S, Rodríguez-Márquez A, Orozco-Suárez S et al. · 2026 · Basic & clinical pharmacology & toxicology
Vascular relaxation induced by 5-HT 2B receptor is thought to be mediated by stimulation of endothelial nitric oxide synthase (eNOS), but this assumption still requires investigation. To investigate potential mechanisms, BW723C86 (5-HT 2B…
View details →Torres-Huerta A, Ruley-Haase K, Boger-May A et al. · 2026 · Journal of immunology (Baltimore, Md. : 1950)
The cause of inflammatory bowel disease (IBD) is not known, but both innate and adaptive immunity contribute to IBD pathogenesis. To better understand the contributions of innate immunity to IBD, we have generated a mouse model of IBD that…
View details →Aragone L, Burbano P, Cameron A et al. · 2026 · Annals of surgical treatment and research
Purpose A Suffocating Neck Hematoma (Snh) Is A Rare But Potentially Fatal Surgical Complication Of Thyroidectomy. In An Effort To Reduce Its Incidence, Many Surgeons Opt For The Selective Use Of Drains. However, There Are No Studies…
View details →Szlufik S, Duszyńska-Wąs K, Koźmińska A et al. · 2026 · Neurologia i neurochirurgia polska
Introduction Bilateral subthalamic nucleus deep brain stimulation (DBS STN) is a very effective surgical method of treating motor symptoms in Parkinson's disease (PD) patients. The long-term cognitive outcome after the surgery is still…
View details →Lagacé JC, St-Martin P, Avino M et al. · 2026 · Experimental physiology
Prolonged bed rest and immobilization have deleterious effects on skeletal muscle mass and function, especially in older adults. These can lead to reduced physical capacity and quality of life. Previous experiments in younger individuals…
View details →Stadie N, Heinzer R, Marques-Vidal P · 2026 · European journal of nutrition
PURPOSE: Many individuals turn to supplements like magnesium, believing them to offer a natural way to improve sleep quality. Yet, research on magnesium’s effects has produced inconsistent results. We assessed the relationships between…
View details →Thomas S, Ben-Davies R, Cetinkaya-Fisgin A et al. · 2026 · Journal of the peripheral nervous system : JPNS
Background and aims Recent preclinical studies have shown that nicotinamide adenine dinucleotide (NAD + ) plays a critical role in molecular mechanisms of axon degeneration, and reductions in NAD + levels are associated with axonal…
View details →Battistelli LS, Moraes RM, Santos YC et al. · 2026 · Journal of periodontology
Background Recent findings have associated alveolar bone loss (ABL) with the presence of senescent cells. Aging and the accumulation of senescent cells are associated with a pro-inflammatory environment which may exacerbate tissue damage.…
View details →Spormann S, Lebre M, Moutinho-Pereira J et al. · 2026 · Journal of plant physiology
Wild tomato species (WTS) have long been attracting the attention of plant researchers due to their ability to tolerate harsh environmental conditions in their natural habitats. In this context, their use in grafting procedures, where they…
View details →Espelta JM, Viana‐Soto A, Molowny‐Horas R et al. · 2026 · Journal of Applied Ecology.
While disturbances are essential for biodiversity, their escalation driven by climate change may threaten forest ecosystems. Contrasting approaches to adapt forests to disturbances-intensifying management versus encouraging natural…
View details →Ruocco-Vetucci V, Chaves RAC, Ballan ACF et al. · 2026 · General dentistry
Considering that osteonecrosis of the jaw may be due to the antiangiogenic effect of bisphosphonates and that leukocyte- and platelet-rich fibrin (L-PRF) releases proangiogenic factors, this study hypothesized that L-PRF could prevent…
View details →Al-Haddad C, Kobeissi H, Wehbi Z et al. · 2026 · Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus
Purpose To assess the driving performance and visual attention of amblyopic drivers using a driving simulator integrated with eye tracking technology in an urban setting. Methods A total of 30 participants were enrolled: 14 amblyopic…
View details →Cao X, Francisco CO, TaghiBeyglou B et al. · 2026 · Sleep & breathing = Schlaf & Atmung
PURPOSE: The recumbent posture during sleep increases small airway narrowing and nocturnal asthma despite optimal asthma treatment. Fluid accumulation in the chest can narrow the airway lumen, contributing to small airway narrowing. We…
View details →Lu X, Han Y, Song J et al. · 2025 · Frontiers in endocrinology
Background Recent studies have focused on investigating the role of cellular senescence in ovarian aging. Targeting cellular senescence has been proposed as a potential strategy to improve ovarian aging. p16 and p21 are classical molecules…
View details →He M, Wang L, Zhang S et al. · 2025 · Preprint
Abstract Purpose To investigate the effect of nightly 0.01% atropine eye drops on choroidal thickness (ChT) in pre-myopic children (at risk of myopia). Methods A 12-month randomized, double-blind, placebo-controlled trial was conducted in…
View details →Rodríguez-Arias M, Malaguarnera M, Ribes-Catalá M et al. · 2026 · Behavioral neuroscience
Social defeat (SD) is a well established model that increases addiction vulnerability accompanied by depressive- and anxiety-like behaviors. Environmental enrichment (EE) has been shown to enhance resilience and mitigate stress-induced…
View details →Leitão EPT, Del Rosario H, Hernández I et al. · 2026 · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
By 2030, the incidence of new cases of cancer worldwide is expected to have increased by 18.1%, with a 22% increase in mortality. Leukaemia is the most common childhood cancer, and drug resistance remains a major therapeutic challenge.…
View details →Zhang H, Patton HN, Nagahawatte ND et al. · 2026 · Neurogastroenterology and motility
Background Stomach contractions are coordinated in part by bioelectric slow waves (SW). Dysfunctional SWs are associated with motility disorders. Electrical pacing is a potential strategy for managing motility disorders but remains poorly…
View details →Song JH, Kim SY, Lee YJ et al. · 2026 · Surgery
Background The use of postoperative antibiotics in patients with nonperforated appendicitis remains controversial, with limited evidence supporting routine administration. However, certain intraoperative findings, such as gangrenous,…
View details →Barbarot S, Aubert H, Boivin M et al. · 2026 · The British journal of dermatology
Background New primary preventive therapeutic strategies for atopic dermatitis (AD) are needed. Atopic diseases are associated with disrupted gut microbial balance in early life, suggesting that optimizing microflora through intervention…
View details →Altvater EE, Kojh D, Huang R et al. · 2025 · Preprint
ABSTRACT In metabolic dysfunction-associated steatotic liver disease (MASLD), liver fibrosis is the most important prognostic factor, and fibrosis can lead to hepatic cirrhosis and cancer. In the liver toll-like receptor 4 (TLR4) signaling…
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