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Browse the failure-mode index

21,266 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen accessMedicine

Prospective associations between parental warmth and knowledge in late adolescence and depression and anxiety symptoms in young adulthood: a Swedish cohort study.

Saminathen MG, Lundin A, Raninen J et al. · 2026 · BMC public health

Background Parenting practices, such as emotional support and warmth, are key determinants of adolescent mental health, whereas the role of parental knowledge is less well understood. Parental warmth is thought to foster openness and…

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Negative / Null Result Report

Analysis of expression Quantitative Trait Loci for NLGN4X in relation to language and neurodevelopmental function: an exploratory analysis using FUSION and GTEx workflows

Simpson NH, Bishop DV, Newbury DF · 2021 · Preprint

Language disorders in children are highly heritable, but progress in identifying genetic variants that contribute to language phenotypes has been slow. Here we applied a novel approach by identifying SNPs that are associated with gene…

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Negative / Null Result ReportOpen accessMedicine

Neoadjuvant Therapy for Localized Pancreatic Cancer.

McKean J, Underwood P, Yasinzai AQK et al. · 2026 · Cancers

Background/objectives Pancreatic ductal adenocarcinoma is an aggressive malignancy with poor long-term survival. While surgical resection followed by adjuvant chemotherapy remains the standard of care for resectable disease, a substantial…

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Negative / Null Result ReportOpen accessMedicine

Examining the relationship between problematic social media use and caffeine use disorder in the context of physical activity: a cross-sectional moderation study among university students.

Orhan BE, Karadağ B, Alkasasbeh WJ et al. · 2026 · Frontiers in nutrition

Introduction Problematic social media use (PSMU) and caffeine use disorder (CUD), a behavioral pattern without formal diagnostic status and a DSM-5 condition listed for further study, respectively, share phenomenological features…

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Negative / Null Result ReportOpen accessMedicine

Does Pain Self-efficacy influence Initial Forward Bending in Adults with Chronic Low Back Pain following Exercise? A Cohort Study.

McManus F, Pranata A, Simpson JA et al. · 2025 · International journal of sports physical therapy

Background/purpose Chronic low back pain affects how individuals bend. Whether pain self-efficacy, a term describing one's confidence in their ability to perform activities despite experiencing pain, affects how much people with chronic…

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Negative / Null Result ReportOpen accessMedicine

Woody seeds and seedlings are unresponsive to herbivore kairomones.

Headrick KC, Pellegrini BA, Santiago EM et al. · 2026 · AoB PLANTS

Herbivory is particularly threatening to young plants that lack the resources needed to survive an attack. Seeds and seedlings should thus benefit greatly from using pre-attack cues to induce defence before damage. Locomotion mucus from…

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Negative / Null Result ReportOpen accessMedicine

Does civilian oversight impact police legitimacy?

Schiff KJ, Schiff DS, Moy BJ et al. · 2025 · PNAS nexus

Does the implementation of external oversight in policing improve public perceptions of police legitimacy? Civilian review boards (CRBs) are frequently promoted as mechanisms to enhance the legitimacy of police agencies by providing…

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Negative / Null Result ReportOpen accessMedicine

Infants Do Not Reliably Track When Bilingual Speakers Switch Languages.

Potter CE, Lew-Williams C · 2025 · Behavioral sciences (Basel, Switzerland)

It is a widely held belief that bilingual infants benefit from hearing each of their languages spoken by different people, as speakers could serve as a cue for separating the two languages. However, it is not yet known whether infants…

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Negative / Null Result ReportOpen accessMedicine

Fascia-Focused Versus Conventional Physiotherapy for Chronic Low Back Pain and Comorbid Depression in Psychosomatic Inpatients.

Overmann L, Steinmeier K, Brandl A et al. · 2026 · Journal of clinical medicine

Background: Chronic low back pain (CLBP) and depression often co-occur. This study compared a fascia-focused physiotherapeutic program with a conventional physiotherapeutic and relaxation-based program in psychosomatic inpatients with CLBP…

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