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Browse the failure-mode index

21,257 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen accessMedicine

Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers in Patients Undergoing Aortic Valve Replacement for Severe Aortic Stenosis: A Retrospective Cohort Study.

Abid H, Khan Y, Khan N et al. · 2026 · Journal of clinical medicine

Background: Angiotensin-converting enzyme inhibitors (ACEis) and angiotensin receptor blockers (ARBs) were historically considered contraindicated in severe aortic stenosis (AS) due to theoretical haemodynamic risks. Contemporary evidence…

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Negative / Null Result Report

High Variability in Resistance to Deformation Under Valgus Load of Knee Braces used for the Treatment of Medial Collateral Ligament Tears: A Comparative Biomechanical Analysis

Pechlivanidou E, Stacheter M, Wahl P et al. · 2026 · Preprint

Abstract Introduction To quantify valgus deformation and per-load mechanical stiffness of commercially available knee braces indicated for medial collateral ligament (MCL) injuries, and to evaluate whether mechanical performance is…

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Negative / Null Result ReportMedicine

Art v 3 sensitization is associated with increased immunological complexity but not clinical severity in lipid transfer protein syndrome.

Carbonell Martínez A · 2026 · European annals of allergy and clinical immunology

Summary Background. Lipid transfer protein (LTP)-mediated food allergy represents one of the most severe and heterogeneous forms of IgE-mediated food allergy in Mediterranean populations. Although Pru p 3 is the main marker of LTP…

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Negative / Null Result ReportMedicine

Surface Texture of Taste Carriers Modulates Bitter Taste Identification.

Brothánková P, Faitlová H, Sitina M et al. · 2026 · ORL; journal for oto-rhino-laryngology and its related specialties

Aim The aim of this study was to assess the relationship between texture and the correct identification of gustatory stimuli (sweet, salty, bitter, and sour) in both healthy participants and patients with taste disorders. Patients and…

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Negative / Null Result ReportMedicine

Fostering a Reflecting Processing of the Academic Crisis: The Effectiveness of Group Counselling for Underachieving University Students.

Esposito G, Passeggia R, Cannata A et al. · 2026 · Healthcare (Basel, Switzerland)

Background: University counselling services provide essential support for students navigating critical academic phases. These services have proven to be successful in promoting long-term psychological well-being and student retention.…

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Negative / Null Result ReportOpen accessMedicine

Comparison of the Effects of Intraoperative Dexmedetomidine and Fentanyl Infusion on Postoperative Agitation and Analgesia in Pediatric Patients Undergoing Tonsillectomy and Adenoidectomy: A Prospective Randomized Trial.

Gul YG, Yildiz S, Güngör H et al. · 2026 · Children (Basel, Switzerland)

Background/Objectives: Postoperative agitation (PA) and postoperative pain in pediatric patients following sevoflurane anesthesia are challenging clinical scenarios. This study aimed to evaluate the effects of intraoperative…

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Negative / Null Result Report

Deep Vein Thrombosis Detected After Oral Cancer Reconstructive Surgery: A Single- Center Retrospective Cohort Study With Routine Postoperative Ultrasonographic Screening

Shimojukkoku Y, Yoshida K, Matsui K et al. · 2026 · Preprint

Abstract Background Deep vein thrombosis detected after oral cancer reconstructive surgery may affect postoperative management, but procedure-specific risk factors remain insufficiently defined. Methods We retrospectively reviewed 201…

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Negative / Null Result ReportOpen accessMedicine

Subfoveal Choroidal Thickness in Clinically Significant Pseudophakic Cystoid Macular Edema: An Interocular Comparison with Contralateral Pseudophakic Eyes.

Demir K, Çelik E · 2026 · Clinical ophthalmology (Auckland, N.Z.)

Purpose To evaluate subfoveal choroidal thickness (SCT) in eyes with clinically significant pseudophakic cystoid macular edema (PCME) and compare it with the contralateral pseudophakic eyes that underwent uncomplicated cataract surgery…

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Negative / Null Result ReportMedicine

Are In-Home and Foster Care Services Associated With Risk of Maltreatment-Related Fatality and Near Fatality Following a Child Protection Case? Evidence From Pennsylvania.

Jones DM, Connell CM, Font SA · 2026 · Child maltreatment

Many children who experience child maltreatment fatalities (CMF) or near fatalities (CMNF) are previously known to the child welfare system (CWS). Although in-home services and foster care (FC) are tools for preventing CMF/CMNF, relatively…

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Negative / Null Result ReportMedicine

Match outcome influences accumulated but not relative external load in rolling small-sided games with loser rotation.

Dalen T, Stallvik M, Lagestad P et al. · 2026 · BMC sports science, medicine & rehabilitation

This study investigated whether match outcome influences external training load in a rolling three-team small-sided game (SSG) format in semi-professional male football players. Twenty outfield players contributed valid GPS data across…

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Negative / Null Result ReportOpen accessMedicine

Level-specific impairment of the 10-second grip-and-release test and grip strength in degenerative cervical myelopathy: analysis of 39 surgical cases.

Kobayashi H, Watanabe K, Otani K et al. · 2026 · BMC musculoskeletal disorders

PURPOSE: To characterise the relationship between the 10-second grip-and-release test (GRT) and grip strength—simple measures of upper limb function in degenerative cervical myelopathy (DCM)—with the responsible level. METHODS: We…

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Negative / Null Result ReportOpen accessMedicine

Indocyanine green near-infrared fluorescence angiography in free parascapular flaps: Distal flap perfusion assessment in a retrospective study of 112 cases.

Knoedler L, Thomas B, Mayer S et al. · 2026 · JPRAS open

Background Reliable perfusion of the distal portion of free parascapular (PSC) flaps is essential for successful lower extremity reconstruction. We hypothesized that intraoperative indocyanine green near-infrared video angiography…

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Negative / Null Result ReportMedicine

Effects of vocal hygiene education program delivered via videoconference on acoustic and self-reported voice outcomes in Muslim religious officials in Turkiye.

Yesilli-Puzella G, Hanbal-İbooğlu E, Karataylı Özgürsoy S · 2026 · Scientific reports

This study examined the effects of a vocal hygiene education program delivered via videoconference on voice quality and self-perceived vocal outcomes among Muslim religious officials in Turkiye. The participants were 26 imams, aged between…

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