Negative / Null Result ReportOpen accessComputer Science
Salman Khawar, Yingdan Lu, Yilang Peng et al. · 2026 · arXiv
The rapid proliferation of visual content raises fundamental questions about how different visual formats and features shape perceived credibility. Drawing on processing fluency theory, this research examines how visuals shape credibility judgments. We focus on three popular formats-photos, infographics, and data visualizations-comparing them to text-only posts, and test how two visual features, aesthetic appeal and production quality, influence credibility through processing fluency as a mediating mechanism. Through a preregistered experiment with 1200 US participants, we found that visual po
View details →Negative / Null Result ReportOpen accessPhysics
A. Boughena, S. Benalia, O. Cheref et al. · 2021 · arXiv
Topological nontrivial nature are the latest phases to be discovered in condensed matter physics with insulating bulk band gaps and topologically protected metallic surface states; they are one of the current hot topics because of their unique properties and potential applications. In this paper, we have highlighted a first-principles study of the structural stability and electronic behavior of the Na${}_{2}$AgX (X= As, Sb and Bi) full Heusler compounds, using the Full-Potential Linear Muffin-Tin Orbital (FP-LMTO) method. We have originated that the Hg${}_{2}$CuTi structure is appropriate in a
View details →Negative / Null Result ReportMedicine
Uyanık G, Yüksel M, Abay M et al. · 2026 · Animal reproduction science
This study aimed to evaluate the effects of TAK-683 administered to suckling goats in lactational anestrus on the 4th day (D4) after mating on luteal function, serum progesterone (P₄) levels, and reproductive performance. Forty-five Aleppo…
View details →Negative / Null Result ReportMedicine
Gardner JD, Triadafilopoulos G · 2026 · Digestive diseases and sciences
Purpose For unclear reasons, up to 50% of subjects with gastroesophageal reflux disease have an inadequate symptomatic response to treatment with a proton pump inhibitor. Our primary objective was to examine esophageal acid in subjects who…
View details →Negative / Null Result ReportOpen accessMedicine
Huang Y, Chen Q, Chen R et al. · 2025 · BMC gastroenterology
OBJECTIVE: To explore disease severity thresholds beyond which endoscopic intervention fails to reduce mortality in the context of renal insufficiency and upper gastrointestinal bleeding (UGIB), and to develop predictive models for…
View details →Negative / Null Result ReportMedicine
Lee KA, Kim YH, Kim HS · 2026 · Clinical rheumatology
Objectives To evaluate the diagnostic concordance between salivary gland ultrasound (SGUS) and minor salivary gland biopsy (MSGB) in suspected primary Sjögren disease (SjD), and to assess the added value of Doppler ultrasound and extended…
View details →Negative / Null Result ReportOpen accessMedicine
Schmidt US, Van Rickstal R, Van Goethem V et al. · 2026 · Palliative medicine
Background Supporting psychoeducational functioning for advanced cancer patients and informal caregivers (dyads) can be challenging. Self-managed digital interventions offer a possible cost-effective alternative but often face low…
View details →Replication FailureOpen accessMedicine
Fritz CK, de Leão AAP, Sbalqueiro FVF et al. · 2026 · Jornal de pediatria
Objective This study aims to evaluate the quality of life (QoL) and glycemic control of children and adolescents living with type 1 diabetes mellitus (T1D) before and after an intervention with a multidisciplinary educational program.…
View details →Replication FailureMedicine
Carra RB, Garcia LÁL, Menezes JR et al. · 2025 · Movement disorders : official journal of the Movement Disorder Society
Background Epidural electrical spinal cord stimulation has been studied for more than a decade for Parkinson's disease symptoms, but compelling evidence for its effectiveness is still lacking. Objective The aim of this study was to…
View details →Replication Failure
Wang Q, Kimura Y, Oba J et al. · 2025 · Preprint
Background: Kawasaki disease (KD) is an acute, pediatric vasculitis associated with coronary artery abnormality (CAA) development. Echocardiography at month 1 post-diagnosis remains the standard for CAA surveillance despite limitations,…
View details →Negative / Null Result ReportMedicine
de Freitas ALS, Guth G, Araújo ALD et al. · 2026 · Archives of oral biology
Objective To investigate the temporal evolution and predictive value of individual histopathological features of oral epithelial dysplasia (OED) during carcinogenesis, and to evaluate the diagnostic utility of optical fluorescence imaging…
View details →Negative / Null Result ReportOpen accessMedicine
Barham E, Khan M, Del-Cristo M et al. · 2026 · Cureus
Chylothorax, a rare complication of hepatic cirrhosis, is often under-recognized in the absence of ascites or other classical signs of portal hypertension. The diagnosis can be challenging due to its infrequent presentation, which…
View details →Negative / Null Result ReportOpen accessMedicine
Lee KK, Lin YN · 2026 · Cureus
Non-purulent skin and soft tissue infections (NP-SSTIs) are commonly managed with antibiotic therapy; however, a subset of patients demonstrate inadequate clinical response and develop refractory disease. At present, no standardized…
View details →Negative / Null Result ReportMedicine
Dirisala A, Uchida S, Toh K et al. · 2025 · Journal of Controlled Release
Polycation-based mRNA delivery systems have an issue with mRNA integrity in the physiological milieu, particularly in blood compartments, despite their vast potential in mRNA therapeutics. Without comprehensive mechanistic analyses, design…
View details →Negative / Null Result ReportMedicine
Pouplard C, Charuel N, Archer E et al. · 2026 · International journal of laboratory hematology
Background Immunoassays detecting anti-PF4/H antibodies must be sensitive to exclude heparin-induced thrombocytopenia (HIT), and optical density (OD) values are useful for confirming HIT, but no calibration is currently available.…
View details →Negative / Null Result Report
Biswas B, van Bergen E, Vaello T et al. · 2025 · Preprint
Plants and herbivorous insects are engaged in long-term coevolutionary arms races, where gains in novel plant defences and corresponding adaptations in herbivores may drive evolutionary change. One such recent innovation is the gain of…
View details →Negative / Null Result ReportOpen accessMedicine
Kaur J, Yogesvaran R, Mohd Khialdin S et al. · 2025 · Cureus
A 72-year-old male patient with multiple comorbidities was under our follow-up for bilateral advanced pseudoexfoliative glaucoma with uncontrolled intraocular pressure (IOP) despite maximum medical therapy. He had previously received…
View details →Negative / Null Result ReportOpen accessMedicine
Benamou A, El Moudane A, Barki A · 2026 · Cureus
Intravesical instillation of Bacillus Calmette-Guérin (BCG) is the standard adjuvant treatment for non-muscle-invasive bladder cancer. Although highly effective, BCG therapy may be associated with rare but potentially severe systemic…
View details →Methods Dead-EndMedicine
Grant RC, He JC, Liu N et al. · 2025 · JAMA oncology
Importance Cisplatin is a widely used treatment for cancer that can permanently damage the kidneys. Treatment modifications and other strategies may prevent chronic kidney disease (CKD) in patients at risk; however, the incidence and…
View details →Negative / Null Result ReportOpen accessMedicine
Hackett GI · 2025 · The world journal of men's health
TRAVERSE (TheRapy for Assessment of long-term Vascular events and Efficacy ResponSE in hypogonadal men) is multicentre randomized, double-blind, placebo-controlled, noninferiority trial of testosterone therapy, enrolling 5,246 men 45 to 80…
View details →Failed Experiment ReportOpen accessMedicine
Ciuro M, Sangiorgio M, Cantone G et al. · 2025 · Biology
Spinal cord injury leads to permanent neurological deficits, and aging further diminishes the plasticity and regenerative responses required for recovery. Activation of the Sonic hedgehog (Shh) pathway through the receptor Smoothened (Smo)…
View details →Negative / Null Result ReportMedicine
El Housheimi A, Tato Varela S, Kuhn WC · 2026 · Oncology research and treatment
Background Ovarian cancer (OC) accounts for the most cancer deaths in women worldwide, despite it being the 8th most common one. Almost two-thirds or OC cases present in advanced stages (III/IV) and will require maintenance therapy lasting…
View details →Negative / Null Result ReportOpen accessMedicine
Mano T · 2025 · Clinical medicine insights. Case reports
Cervical traction therapy is commonly used for cervical spondylosis; however, complications, such as subdural hematomas can occur. Possible mechanisms include cerebrospinal fluid (CSF) leakage and bridging vein damage. A 51-year-old…
View details →Negative / Null Result ReportOpen accessMedicine
Serour MH, Mohammad H, Aziza O et al. · 2026 · Journal of surgical case reports
Chronic diabetic foot ulcers remain a major clinical challenge, particularly when complicated by tendon exposure and failure to respond to standard care. We report a 47-year-old male with Type II diabetes mellitus with a history of smoking…
View details →Replication FailureMedicine
Gootjes EC, Bakkerus L, Adhin AA et al. · 2026 · JAMA
Importance Local therapy, including surgery, radiation, and ablation, is increasingly used in patients with multiorgan metastatic colorectal cancer (mCRC). However, prospective evidence for a survival benefit of tumor debulking is lacking.…
View details →Replication FailureOpen accessMedicine
Yano K, Ishida T, Yokosuka K et al. · 2026 · Internal medicine (Tokyo, Japan)
Tumor management is the cornerstone of treatment for anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis that is refractory to immunosuppressive therapy. However, little is known about the effectiveness of chemotherapy for…
View details →Negative / Null Result ReportMedicine
Kankotia S, Park S, Thomas J · 2025 · Current opinion in oncology
Purpose of review Relapsed or metastatic head and neck squamous cell carcinoma (R/M HNSCC) is a deadly disease that historically was treated with palliative chemotherapy-based regimens. Since 2019, immunotherapy-based regimens have become…
View details →Negative / Null Result ReportOpen accessMedicine
Glauser G, Kvint S, Ramayya AG et al. · 2025 · Neurosurgery practice
Background and objectives The purpose of the present work was to review our series of patients with far lateral disk herniations treated by the intertransverse approach. Methods Patients undergoing intertransverse approach to treat…
View details →Failed Experiment ReportMedicine
Tian F, Hu C, Liu W et al. · 2025 · The American journal of cardiology
Myocardial work (MW) by noninvasive pressure-strain loop (PSL) is a novel echocardiographic tool that provides a more precise estimation of right ventricular (RV) performance by accounting for the RV loading conditions. The study sought to…
View details →Negative / Null Result Report
Childs H, Zhou P, Donald BR · 2025 · Preprint
Due to their favorable therapeutic properties, including improved stability, bioavailability, and membrane permeability, D-peptides that bind biological L-proteins represent an important class of systems in computational drug design. A…
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