Negative / Null Result ReportMedicine
Amodeo AL, Giaquinto V, Reginelli F et al. · 2026 · Psychological reports
The present study examines the associations between other-oriented perfectionism and individual stress within romantic relationships, focusing on the intervening role of social media use as a relational context. Data were collected through…
View details →Failed Experiment ReportMedicine
Portero-Prados FJ, Pabón-Carrasco M, Ponce-Blandón JA · 2026 · Intensive & critical care nursing
Objectives To compare the effectiveness and dermatological safety of chlorhexidine gluconate (CHG)-impregnated dressings versus conventional transparent dressings in preventing central line-associated bloodstream infection (CLABSI) in…
View details →Negative / Null Result Report
Remmerswaal R · 2026 · Preprint
Abstract This study validates and extends the L2 Willingness to Communicate (WTC) scale by incorporating Virtual Exchange (VE) scenarios into the established L2 WTC-R framework. Using two independent samples of Japanese university EFL…
View details →Negative / Null Result Report
Güngör E, Birbilen AZ, Yildiz LA et al. · 2026 · Preprint
Abstract Purpose Early identification of pediatric trauma patients requiring life-saving interventions (LSIs) is fundamental for optimizing emergency triage and allocation planning. This study aimed to evaluate and compare the predictive…
View details →Negative / Null Result ReportMedicine
Jeremias Macedo M, Beirão B, Rodrigues R et al. · 2026 · Blood purification
Introduction Depression is the most prevalent psychiatric disorder among patients with end-stage renal disease receiving hemodialysis (HD), associated with reduced quality of life, poor treatment adherence, higher hospitalization rates,…
View details →Negative / Null Result ReportMedicine
Streubel PN, Sahoo S, Zhang C et al. · 2026 · Journal of shoulder and elbow surgery
Background This study aimed to investigate the associations of general patient and disease-specific factors with baseline patient reported outcome measures (PROMs) in patients undergoing revision rotator cuff repair (RCR). Baseline…
View details →Negative / Null Result ReportMedicine
McGranahan MJ, Sabino-Carvalho JL, Zanuzzi MG et al. · 2026 · American journal of physiology. Regulatory, integrative and comparative physiology
Individuals with posttraumatic stress disorder (PTSD) are at elevated risk for cardiovascular disease (CVD). Emerging research suggests that increased blood pressure variability (BPV) reflects abnormalities in autonomic regulation and may…
View details →Negative / Null Result ReportOpen accessMedicine
Imantika E, Praharsini RK, Sasotya RM et al. · 2026 · Narra J
Obstetric anal sphincter injury (OASIS) may lead to persistent sexual and bowel dysfunction, even after surgical repair. Evidence on the functional outcomes after sphincterorrhaphy and perineoplasty remains limited, particularly in…
View details →Negative / Null Result ReportMedicine
Wang L, Yao L, Wan J et al. · 2026 · Annali italiani di chirurgia
Aim This study aims to identify independent risk factors for tumor recurrence and postoperative complications in platinum-resistant ovarian cancer patients undergoing cytoreductive surgery. Methods This study retrospectively included 96…
View details →Negative / Null Result ReportOpen accessMedicine
Eruysal E, Ravdin L, Iadecola C et al. · 2026 · Journal of Alzheimer's disease : JAD
BackgroundResistin is a circulating protein linked to systemic metabolic disorders and inflammation, both of which can contribute to the pathogenesis of Alzheimer's disease (AD). However, the role of resistin during the preclinical stage…
View details →Negative / Null Result Report
Pham QL, Thai HTK, Huynh NN et al. · 2026 · Preprint
Abstract This study examines whether financial deepening continues to promote economic growth in a high-credit transition economy or whether diminishing marginal returns emerge once financial depth surpasses a critical threshold. Using…
View details →Negative / Null Result ReportOpen accessMedicine
Elhaw KA, Abdelhakim AA, Dominguez J A et al. · 2026 · BMC oral health
Background Removal of impacted mandibular third molars is associated with postoperative discomfort and delayed bone healing. Er:YAG laser osteotomy has been proposed as a minimally invasive alternative to conventional rotary…
View details →Negative / Null Result ReportOpen accessMedicine
Wesołowski I, Dzienisiewicz J, Langa D et al. · 2026 · Nutrients
Background/Objectives : Although creatine monohydrate is widely recognized as an effective ergogenic aid in strength and power sports, its role in endurance and mixed-sport disciplines remains less clearly established. This scoping review…
View details →Negative / Null Result ReportOpen accessMedicine
Lynghaug T, Fuskevåg OM, Storm BS et al. · 2026 · Acta anaesthesiologica Scandinavica
Background Tranexamic acid is an antifibrinolytic agent reducing mortality when administered to trauma patients with haemorrhagic shock. This mortality reduction is time sensitive. Increased intramuscular dose administration has proven an…
View details →Negative / Null Result ReportOpen accessMedicine
Barot S, Andersson-Franko M, Ghazi S et al. · 2026 · American journal of clinical pathology
Objectives Tumor budding is an emerging micromorphologic predictor of recurrence in localized colorectal cancer (CRC). Whether its addition to established CRC recurrence risk factors routinely assessed in clinical practice improves…
View details →Negative / Null Result ReportMedicine
Bhattacharjee B, Ghosh S, Basu N et al. · 2026 · Journal of integrative and complementary medicine
Objectives To assess the feasibility of conducting a randomized controlled trial and to explore preliminary effects of individualized homoeopathic medicines (IHMs) compared with placebo in patients with temporomandibular joint dysfunction…
View details →Negative / Null Result ReportMedicine
El-Sherif S, Imam M, Hassan M et al. · 2026 · Clinical rheumatology
Background Sacroiliac joint (SIJ) pain is a prevalent yet underappreciated source of LBP, with multiple etiologies and therapeutic options. Failure of the conservative approach necessitates interventional injections, especially with…
View details →Negative / Null Result Report
Bowen HP, O’Loughlin G, Schleicher C et al. · 2026 · Preprint
Background The impact of the Inflation Reduction Act (IRA) upon late-stage developments has been assumed to be limited. The Congressional Budget Office’s IRA analysis excluded post-approval innovation, potentially overlooking substantial…
View details →Negative / Null Result ReportMedicine
Gu X, Liu J, Wang H et al. · 2026 · Frontiers in public health
Objective To analyze the association between short-term exposure to air pollutants and the risk of fatal recurrence within 1 year in patients with first-episode acute hemorrhagic stroke, to provide scientific basis for health management…
View details →Negative / Null Result ReportOpen accessMedicine
Abrantes-Soares F, Santos MM, Mariana M et al. · 2026 · Journal of xenobiotics
In recent years, bisphenol F (BPF) and bisphenol S (BPS) have been used in several everyday products to replace bisphenol A (BPA), since exposure to BPA has been associated with the development of several pathologies. However, recent…
View details →Negative / Null Result ReportOpen accessMedicine
Conde-Disla E, González-Olmo MJ, Olmos-Valverde M et al. · 2026 · Dentistry journal
Background: Pain during orthodontic debonding is a common clinical concern. Although previous studies have mainly focused on mechanical approaches to reduce discomfort, the influence of emotional characteristics of patients on pain…
View details →Negative / Null Result ReportOpen accessMedicine
Xu X, Zhang B, Wang X et al. · 2026 · Orthopaedic surgery
Objective There is no consensus on the age restriction for total ankle arthroplasty (TAA) patients. The aim of our study was to analyze the clinical function, radiographic outcomes, patient satisfaction, and complications between patients…
View details →Negative / Null Result ReportOpen accessMedicine
Agarwal P, Kumar P, Chugh VK et al. · 2026 · Cureus
Background and aim Postoperative pain following root canal treatment (RCT) can be influenced by the obturation technique, as variations in apical sealing and material extrusion may affect periapical tissue response. The aim of this study…
View details →Negative / Null Result ReportOpen accessMedicine
Lopresti AL, Smith SJ, Ferdinands FR · 2026 · Frontiers in reproductive health
Background Khaya senegalensis is a tree species that has traditional use for the alleviation of menstrual and hormonal symptoms in women. Moreover, supplementation with a Khaya senegalensis preparation (Khapregesic®) was associated with…
View details →Negative / Null Result ReportOpen accessMedicine
Mousa N, Hasan AK · 2026 · Cureus
Background This study aimed to evaluate nasal morphological characteristics and their relationship with vertical facial growth patterns in a Syrian adult population using lateral cephalometric analysis. Methodology This retrospective…
View details →Negative / Null Result ReportOpen accessMedicine
Atsuta S, Koizumi S, Takahashi SS et al. · 2026 · Dentistry journal
Background/Objectives : Acceleration of orthodontic tooth movement remains a major challenge in clinical orthodontics. Evidence suggests that increased local blood flow around the alveolar bone is key to bone remodeling and potentially…
View details →Replication FailureOpen accessMedicine
Yiğit N, Nazlıgül AS, Ülgen NK et al. · 2026 · Geriatric orthopaedic surgery & rehabilitation
Background Distal radius fractures are common among elderly patients and frequently pose management challenges due to advanced age, multiple comorbidities, and increased anesthesia-related risks. In high-risk individuals with limited…
View details →Replication FailureOpen accessMedicine
Rogalska E, Stenka W, Kupcewicz E et al. · 2026 · Frontiers in public health
Introduction Breast cancer is the most common malignancy among women worldwide. Mastectomy, often accompanied by breast reconstruction, plays a key role in treatment and prevention among high-risk patients; however, psychological outcomes…
View details →Replication FailureMedicine
Nowell S, Fantini O, Roman A et al. · 2026 · Veterinary dermatology
Fluorescent light energy (FLE; Phovia, Vetoquinol) is a photobiomodulation therapy that promotes healing and reduces inflammation. Cutaneous epitheliotropic lymphoma (CTCL) is a neoplastic skin disease with limited treatment options.…
View details →Negative / Null Result ReportMedicine
Pei Y, Jones L, Minga J · 2026 · American journal of speech-language pathology
Purpose This study investigated patterns of question use in conversation among individuals with traumatic brain injury (TBI) by analyzing the frequency, types, and social actions of the questions. Method Questions from conversational…
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