Negative / Null Result ReportMedicine
Xu, Hu, Zhao et al. · 2026 · Obesity (Silver Spring, Md.)
HDM1002, a small-molecule agonist of glucagon-like peptide-1 receptors, was evaluated for safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD). Chinese participants (18-60 years) with…
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Haresh Rengaraj Rajamohan, Yuxuan Chen, Kyunghyun Cho et al. · 2026 · arXiv
This study assesses whether self-supervised learning (SSL) improves knee osteoarthritis (OA) modeling for diagnosis and prognosis relative to ImageNet-pretrained initialization. We compared (i) image-only SSL pretrained on knee radiographs from the OAI, MOST, and NYU cohorts, and (ii) multimodal image-text SSL pretrained on hospital knee radiographs paired with radiologist impressions. For diagnostic Kellgren-Lawrence (KL) grade prediction, SSL yielded mixed results. While image-only SSL improved accuracy during linear probing (frozen encoder), it did not outperform ImageNet pretraining during
View details →Negative / Null Result ReportOpen accessPhysics
Chen Du, Yong-Feng Huang, Zhi-Bin Zhang et al. · 2023 · arXiv
Fast Radio Bursts (FRBs) are bright radio transients with millisecond durations which typically occur at extragalactic distances. The association of FRB 20200428 with the Galactic magnetar SGR J1935+2154 strongly indicates that they could originate from neutron stars, which naturally leads to the expectation that periodicity connected with the spinning of magnetars should exist in the activities of repeating FRBs. However, previous studies have failed to find any signatures supporting such a conjecture. Here we perform a thorough search for short timescale periodicity in the four most active r
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Isobel Falconer · 2016 · arXiv
In 1877 James Clerk Maxwell and his student Donald MacAlister refined Henry Cavendish's 1773 null experiment demonstrating the absence of electricity inside a charged conductor. This null result was a mathematical prediction of the inverse square law of electrostatics, and both Cavendish and Maxwell took the experiment as verifying the law. However, Maxwell had already expressed absolute conviction in the law, based on results of Michael Faraday's. So, what was the value to him of repeating Cavendish's experiment? After assessing whether the law was as secure as he claimed, this paper explores
View details →Negative / Null Result ReportMedicine
Tuncekin, Toprak · 2026 · Iranian journal of immunology : IJI
Rheumatoid arthritis (RA) and ankylosing spondylitis (AS) are chronic autoimmune inflammatory disorders in which TNF-α plays a key role. Anti-TNF agents are widely used in the management of these diseases. Since TNF-α is also…
View details →Negative / Null Result ReportOpen accessComputer Science
K. S. Babu, Sandip Pakvasa · 2002 · arXiv
We show that lepton number violating muon decays, μ^+ -> e^+ + ν_e-bar + ν_i-bar (i=e, μor τ), can consistently explain the neutrino anomaly reported by the LSND experiment. Two effective operators in the Standard Model are identified which lead to just such decays and no other processes. The scale of new physics Λmust be relatively low, Λ< 500 GeV. Extensions of the Standard Model which realize these effective operators are presented. Since new physics affects only the decay of the muon, and not of π^+-, our scenario predicts a null result for ν_μ-bar - ν_e-bar oscillation searches at the Fer
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Alison Knopf · 2023 · Alcoholism & Drug Abuse Weekly
State laws that allow medical cannabis to be prescribed and dispensed did not result in the reduced treatment of chronic noncancer pain, researchers have found. In the study, “Effects of U.S. State Medical Cannabis Laws on Treatment of…
View details →Negative / Null Result ReportOpen accessComputer Science
Jun Zhang, Zhenwei Lyu, Junwu Huang et al. · 2021 · arXiv
Light axion fields, if they exist, can be sourced by neutron stars due to their coupling to nuclear matter, and play a role in binary neutron star mergers. We report on a search for such axions by analysing the gravitational waves from the binary neutron star inspiral GW170817. We find no evidence of axions in the sampled parameter space. The null result allows us to impose constraints on axions with masses below $10^{-11} {\rm eV}$ by excluding the ones with decay constants ranging from $1.6\times10^{16} {\rm GeV}$ to $10^{18} {\rm GeV}$ at $3σ$ confidence level. Our analysis provides the fir
View details →Negative / Null Result ReportOpen accessPhysics
I. Altarev, G. Ban, G. Bison et al. · 2010 · arXiv
Physics at the Planck scale could be revealed by looking for tiny violations of fundamental symmetries in low energy experiments. In 2008, a sensitive test of the isotropy of the Universe using has been performed with stored ultracold neutrons (UCN), this is the first clock-comparison experiment performed with free neutrons. During several days we monitored the Larmor frequency of neutron spins in a weak magnetic field using the Ramsey resonance technique. An non-zero cosmic axial field, violating rotational symmetry, would induce a daily variation of the precession frequency. Our null result
View details →Negative / Null Result ReportOpen accessComputer Science
Arvid Frydenlund · 2024 · arXiv
The recently introduced path-star task is a minimal task designed to exemplify limitations to the abilities of language models (Bachmann and Nagarajan, 2024). It involves a path-star graph where multiple arms radiate from a single starting node and each node is unique. Given the start node and a specified target node that ends an arm, the task is to generate the arm containing that target node. This is straightforward for a human but surprisingly difficult for language models, which did not outperform the random baseline. The authors hypothesized this is due to a deficiency in teacher-forcing
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Shan Gao, Kazumi Kashiyama, Peter Meszaros · 2013 · arXiv
The recent gamma-ray burst GRB 130427A has an isotropic electromagnetic energy $E^{iso}\sim10^{54}$ erg, suggesting an ample supply of target photons for photo-hadronic interactions, which at its low redshift of $z\sim0.34$ would appear to make it a promising candidate for neutrino detection. However, the IceCube collaboration has reported a null result based on a search during the prompt emission phase. We show that this neutrino non-detection can provide valuable information about this GRB's key physical parameters such as the emission radius $R_{d}$, the bulk Lorentz factor $Γ$ and the ener
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Masahiro Ibe, Ryuichiro Kitano · 2007 · arXiv
We find that there is no supersymmetric flavor/CP problem, mu-problem, cosmological moduli/gravitino problem or dimension four/five proton decay problem in a class of supersymmetric theories with O(1) GeV gravitino mass. The cosmic abundance of the non-thermally produced gravitinos naturally explains the dark matter component of the universe. A mild hierarchy between the mass scale of supersymmetric particles and electroweak scale is predicted, consistent with the null result of a search for the Higgs boson at the LEP-II experiments. A relation to the strong CP problem is addressed. We propose
View details →Negative / Null Result ReportOpen accessComputer Science
L. Marsicano, M. Battaglieri, A. Celentano et al. · 2018 · arXiv
Medium-energy electron beam-dump experiments provide an intense sources of secondary muons. These particles can be used to search for muon-coupling light dark scalars that may explain the $(g-2)_μ$ anomaly. We applied this idea to SLAC E137 experiment deriving new exclusion limits and evaluated the expected sensitivity for the planned Jefferson Lab BDX experiment (in case of null result report). The calculation is based on numerical simulations that include a realistic description of secondary muons generation in the dump, dark scalar production, propagation, and decay, and, finally, the decay
View details →Negative / Null Result ReportOpen accessPhysics
EROS collaboration, E. Aubourg, P. Bareyre et al. · 1995 · arXiv
We present results from a search for gravitational microlensing of stars in the Large Magellanic Cloud by low mass objects in the Galactic Halo. The search uses the CCD light curves of about 82,000 stars with up to 46 measurements per night over a period of 10 months. No light curve exhibits a form that is consistent with a microlensing event of maximum amplification greater than 1.2. This null result makes it unlikely that the Halo is dominated by objects in the mass range $5 10^{-8}M_{\odot} < M <5 10^{-4}M_{\odot} $. keywords{Galaxy : Halo, kinematics and dynamics, stellar content -- Cosmol
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Bob de Ruiter · 2021 · arXiv
The goal of this study was to improve the post-processing of precipitation forecasts using convolutional neural networks (CNNs). Instead of post-processing forecasts on a per-pixel basis, as is usually done when employing machine learning in meteorological post-processing, input forecast images were combined and transformed into probabilistic output forecast images using fully convolutional neural networks. CNNs did not outperform regularized logistic regression. Additionally, an ablation analysis was performed. Combining input forecasts from a global low-resolution weather model and a regiona
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Anam Zahra, Pierre-Etienne Martin · 2021 · arXiv
This paper presents a table tennis stroke detection method from videos. The method relies on a two-stream Convolutional Neural Network processing in parallel the RGB Stream and its computed optical flow. The method has been developed as part of the MediaEval 2021 benchmark for the Sport task. Our contribution did not outperform the provided baseline on the test set but has performed the best among the other participants with regard to the mAP metric.
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Nazki, Tennakoon, Reddy et al. · 2026 · The Journal of general virology
Infectious bursal disease virus (IBDV) causes an endemic immunosuppressive disease in chickens. Prior exposure to IBDV influences the pathogenesis and shedding of chicken strains of influenza A virus (IAV), but its effect on waterfowl…
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Olivieri, Amatori, Battocchio et al. · 2026 · Nanomaterials (Basel, Switzerland)
Gold nanorods (AuNRs) were synthesized and optimized with the aim of obtaining strongly hydrophilic nanomaterials, suitable as a drug delivery system (DDS) for copper-based drugs. After careful purification, AuNRs were characterized by…
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Paulina Sowicka, Gerald Handler, David Jones · 2018 · arXiv
We report new observations of the central star of the planetary nebula VV 47 carried out to verify earlier assertions that the short-period pulsation modes detected in the star are driven by the $ε$ mechanism. In our data, VV 47 was not variable up to a limit of 0.52 mmag in the Fourier amplitude spectrum up to the Nyquist frequency of 21.7 mHz. Given this null result we re-analyzed the data set in which oscillations were claimed. After careful data reduction, photometry, extinction correction, and analysis with a conservative criterion of S/N $\geq$ 4 in the Fourier amplitude spectrum, we fou
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Ole B. Suhr, Stellan Mörner, Anders Holmgren et al. · 2011
Septal systolic strain measurements showed reduced longitudinal function but its localized nature failed to demonstrate radial disturbances in patients with pathologically thickened septum. No difference was found in systolic strain…
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Azam Abed, Aliasghar Asghar Nezhad, Hamidreza Hatami · 2015 · Iranian Rehabilitation Journal
Objectives: The aim of current study was the evaluation and comparison of compatibility and marital satisfaction between handicapped couples and healthy ones. Methods: In this study, 50 handicapped couples and 50 healthy couples were examined with Enrich’s marital satisfaction questionnaire and Bell’s adjustment questionnaire. The data were analyzed, using SPSS 15, correlation tests and ANOVA. Results: The results showed that there was no significant difference between handicapped and healthy couples in compatibility and marital satisfaction. Discussion: It is concluded that people
View details →Negative / Null Result ReportOpen accessAgriculture
D Sumner · 1963 · California Agriculture
INITIAL TRIALS in 1961 comparing Piper sudan, SX-11 (a sudan x grain sorghum cross) and NK-300 (a forage sorghum) showed that there was no significant difference in total seasonal yield in dry matter production when used as pasture, although Piper outyielded the other two. When used as green chop there was no significant difference between Piper and SX-11, and both significantly outyielded NK-300. These trials were grown in 12-inch rows and harvested throughout the season as each variety reached 24 inches in height as pasture or 50% late boot stage as green chop.
View details →Negative / Null Result ReportOpen accessAnimal culture
Razia Sultana Janampet, Kishan Kumar Malavath, Rajanna Neeradi et al. · 2016 · Veterinary World
Aim: This study was conducted to evaluate the growth performance and nutrient digestibility of guar meal, an unconventional protein-rich feed ingredient in kids in comparison to conventional groundnut cake. Materials and Methods: A total of 18 kids were randomly allotted to three groups, and T1 group was fed on basal diet, T2 and T3 groups were offered diet replacing groundnut cake at 50% and 100% with guar meal, respectively, for a period of 120-day. At the end of the growth trial, a digestibility trial was conducted to evaluate the nutrient utilization. Results: There was no significant diff
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Ciaffi J, Bordini B, Cosentino M et al. · 2026 · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
Osteoarthritis patients undergoing THA or TKA were studied to compare the cumulative incidence of revision after perioperative denosumab versus alendronate. Denosumab was not associated with differences in the incidence of revision after…
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David R. Hakes, David C. Rose
A number of empirical studies have failed to find a significant relationship between deficits and interest rates. This "non-finding" has become something of a stylized fact among many economists and is often cited as evidence of the…
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I. Lőrincz, M. Tajmar · 2015 · arXiv
A number of weight anomalies have been reported in the past with respect to gyroscopes. Much attention was gained from a paper in Physical Review Letters, when Japanese scientists announced that a gyroscope loses weight up to $0.005\%$ when spinning only in the clockwise rotation with the gyroscope's axis in the vertical direction. Immediately afterwards, a number of other teams tried to replicate the effect, obtaining a null result. It was suggested that the reported effect by the Japanese was probably due to a vibration artifact, however, no final conclusion on the real cause has been obtain
View details →Negative / Null Result ReportMedicine
Rodrigues, Macedo, de Paulo et al. · 2026 · Oral surgery, oral medicine, oral pathology and oral radiology
To evaluate the effects of sticky bone a biomaterial composed of Solid-PRF (S-PRF), a variant of platelet-rich fibrin (PRF), and deproteinized bovine bone-on bone formation after tooth extraction performed prior to radiotherapy, with…
View details →Negative / Null Result ReportOpen accessPsychology
Monalisa Muniz, Ricardo Primi, Fabiano Koich Miguel · 2007 · Psicologia
The Emotional intelligence supposedly is a mediator variable in the stress control although there is no sufficient empirical evidence supporting this relationship. The purpose of the present research was to study the correlation between emotional intelligence and stress. The participants were 24 city guards who answered the Mayer-Salovey-Caruso Emotional Intelligence Tests V2.0 (MSCEIT) and the Lipp’s Inventory of Stress Symptoms for Adults (ISSL). The results showed no significant correlation between stress and the general score of emotional intelligence. However, analyzing the subtasks score
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Seyed Mohammadreza Fatemi Khorasgani, Neda Ramezani, Negar Ebrahimi Varnousfaderani · 2020 · Journal of Research in Medical Sciences
Background: Previous studies report an association between joint hypermobility (JH), as a hallmark of connective tissue disorder, and autonomic dysfunction, digestive problems, and irritable bowel syndrome. However, its association with functional constipation (FC) has not been evaluated. This study is run and implemented to justify this theme/topic. Materials and Methods: In this case–control study among 200 subjects, 100 were of FC according to the ROME III Criteria (case group) and each child was matched for age and gender with a healthy control that did not meet criteria for FC (control gr
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Kencono Viyati, Kinasih Prayuni, Yenni Zulhamidah et al. · 2023 · Makara Journal of Health Research
Background: Asthma is a multifactorial disease that encompasses a multitude of genetic and environmental factors. One such factor is the disintegrin and metalloprotein-33 (ADAM33) gene, which is correlated with asthma and bronchial hyperresponsiveness. Previous studies conducted on Asian populations have reported a significant association between rs2787094 polymorphism in the ADAM33 gene and asthma. Methods: Our study involved 153 Indonesian participants. TaqMan genotyping assay was used to analyze rs2787094 polymorphism in the ADAM33 gene. Results: No significant association was detected betw
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