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WASTE Journal

Browse the failure-mode index

21,697 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Lumbar Function and Muscle Preservation Following Hybrid Surgery Versus Selective Thoracic Fusion in Adolescent Idiopathic Scoliosis: A Preliminary Comparative Study.

Tasdemir, Korkmaz, Durak et al. · 2026 · Turkish neurosurgery

To investigate lumbar motion and muscle change following hybrid surgery in adolescent idiopathic scoliosis (AIS). We conducted a prospective study design including 16 patients (14 female, 2 male) who underwent either hybrid surgery or…

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Failed Experiment ReportMedicine

Evaluation of Neonatal Sprague-Dawley Rats as a Potential Animal Model for the Neurovirulence Test of an Iranian Mumps Vaccine Strain, RS-12.

Mohammad Kazem, Mohammad, Mohammad Hasan et al. · 2025 · Archives of Razi Institute

Mumps virus (MuV), a neurotropic member of paramyxoviridae, causes mumps disease. Since the 1960s, when the first live-attenuated vaccine against the MuV was developed, mumps outbreaks have dramatically decreased. A monkey-based…

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Negative / Null Result ReportMedicine

Randomized Phase II Study of Bortezomib, Lenalidomide, and Dexamethasone (VRD) Versus Lenalidomide and Dexamethasone (RD) in Elderly Patients with Newly Diagnosed Multiple Myeloma (KMM1910).

Yi, Yoon, Lee et al. · 2026 · Cancer research and treatment

While triplet regimens are considered optimal for treatment of multiple myeloma (MM), the benefit of adding bortezomib to lenalidomide and dexamethasone remains prospective-wise unclear in elderly patients due to frailty and potential…

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Negative / Null Result ReportMedicine

Robotic segmental ureterectomy for upper tract urothelial carcinoma: comparable short-term oncological outcomes and improved postoperative recovery compared to open approach.

Lasmanovich, Chepeliuk, Fihman et al. · 2026 · World journal of surgical oncology

Segmental ureterectomy (SU) is an established kidney-sparing strategy for upper tract urothelial carcinoma (UTUC), yet few studies have compared the standard open approach to the emerging robotic modality. We performed a clinical outcome…

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Negative / Null Result ReportMedicine

Impact of the MonCœur smartphone application on self-care and quality of life in heart failure: The APPLIMONCOEUR randomized trial.

Berthelot, Audureau, Bouleti et al. · 2026 · Archives of cardiovascular diseases

The MonCœur smartphone application (app) was developed to meet the specific needs of individuals living with heart failure (HF). To evaluate whether the MonCœur smartphone app improves self-care at 6months in patients with HF,…

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Negative / Null Result ReportMedicine

Impact of virtual reality versus conventional balance training on balance function and fear of falling in older adults: a single blinded, randomized controlled trial.

Shamsoddini, Cheraghifard · 2026 · European geriatric medicine

Balance issues and the fear of falling are among the primary factors contributing to falls in older people, leading to injury and a decline in quality of life. A single-blind, randomized, controlled trial was conducted involving 34 older…

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Failed Experiment ReportMedicine

Antiviral Prophylaxis for Delayed Facial Nerve Palsy Following Vestibular Schwannoma Resection: Single Institutional Series With Systematic Literature Review and Meta-Analyses of 7136 Patients.

Blue, Alvarez, Hines et al. · 2026 · Neurosurgery

Delayed facial nerve palsy (DFNP) is a recognized complication of vestibular schwannoma resection, with proposed mechanisms including viral reactivation, inflammation, and ischemia. Elevated herpes simplex virus and varicella zoster virus…

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Negative / Null Result ReportMedicine

[Evaluation of the Efficacy and Tolerance of Tranexamic Acid Combined with Inoserp TM PAN-AFRICA Antivenom in the Treatment of Hemorrhagic Syndrome during Envenomation by Echis ocellatus in Benin].

Larréché, Sodjinou, Tourita et al. · 2026 · Medecine tropicale et sante internationale

Hemorrhagic syndrome accounts for a significant proportion of the mortality and morbidity associated with snakebites in sub-Saharan Africa. Hyperfibrinolysis, which has been reported in some cases, suggests the potential benefit of…

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Failed Experiment ReportMedicine

Transcranial Direct Current Stimulation Combined with Neurofunctional Motor Training in Autistic Children: A Randomized, Sham-Controlled, Double-Blind Clinical Trial.

Araujo, Araujo, Silva et al. · 2026 · Journal of motor behavior

The study investigated the effects of ten 20-minute sessions of neurofunctional motor training combined with anodal transcranial direct current stimulation (tDCS) over the primary motor cortex or cerebellum on motor skills in autistic…

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Failed Experiment ReportMedicine

Effect of injectable platelet-rich fibrin on orthodontically induced apical root resorption following non-extraction-based orthodontic treatment in adults: A randomized controlled clinical trial.

Idris, Burhan, Hajeer et al. · 2026 · The Journal of international medical research

ObjectiveTo investigate the effect of repeated submucosal administration of injectable platelet-rich fibrin in the buccal region of the lower incisors on orthodontically induced apical root resorption in patients with moderate…

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Negative / Null Result ReportMedicine

A pilot study comparing specimen quality of ESR and EMR.

Metter, Dumoulin, Hay et al. · 2026 · Scandinavian journal of gastroenterology

Endoscopic submucosal resection (ESR) is a novel resection technique. ESR is performed with a partially insulated snare, which allows a resection close to the proper muscle layer thus resecting in the deep submucosa. This should have…

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Negative / Null Result ReportMedicine

Effect of an Educational Intervention on Postural Risk Among Endodontic Residents Under Different Magnification Conditions.

García Alcaide, Conde Villar, Pérez Alfayate et al. · 2026 · European journal of dental education : official journal of the Association for Dental Education in Europe

To assess the impact of a tailored ergonomic lecture on postural risk among second-year endodontic residents depending on the use of no magnification, ergonomic loupes, or an operating microscope. A within-subjects, repeated measures…

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Negative / Null Result ReportMedicine

The Relationship Between Games Missed for Rest or Load Management and Injury in the National Basketball Association, 2014-15 Through 2022-23.

Herzog, Brink, Gondalia et al. · 2026 · Sports medicine (Auckland, N.Z.)

One often-stated aim of load management in elite athletes is injury reduction. However, current literature on the efficacy and effectiveness of specific load management strategies to reduce injury risk is limited. The aim of this study was…

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Negative / Null Result ReportMedicine

Serum fibroblast growth factor-2 and fibroblast growth factor-9 levels in bipolar disorder: Potential biomarkers for mood episodes.

Keskin, Erdoğan, Küçükçetin et al. · 2026 · Psychiatry research

The aim of this study was to compare serum levels of Fibroblast Growth Factor-2 (FGF-2) and Fibroblast Growth Factor-9 (FGF-9) between patients with Bipolar Disorder (BD) and healthy controls (HC), and to evaluate whether these molecules…

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Negative / Null Result ReportMedicine

Long-Term Sedation Effect of Cipepofol Compared to Dexmedetomidine in Patients Receiving Invasive Mechanical Ventilation: A Multicenter, Randomized, Open-Label, Parallel-Controlled Study.

Li, Zhu, Xu et al. · 2026 · Advances in therapy

This study evaluated the efficacy and safety of cipepofol vs. dexmedetomidine for long-term sedation of patients undergoing mechanical ventilation (MV) in an intensive care unit (ICU). Adult patients who required invasive MV for…

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