Negative / Null Result ReportMedicine
Umer H, Mumtaz T, Weiskirchen R et al. · 2026 · Chronobiology international
Disruption of circadian rhythm is common in rotating shift workers, individuals with jet lag, and people with irregular sleep schedules and contributes to metabolic diseases including obesity, type 2 diabetes, metabolic…
View details →Negative / Null Result ReportMedicine
Liu Y, Tao G, Zhao Y et al. · 2026 · Frontiers in medicine
Objective To characterize choroidal structural and perfusion changes in children with emmetropia, low myopia, and moderate myopia using enhanced depth imaging optical coherence tomography (EDI-OCT) and optical coherence tomography…
View details →Negative / Null Result ReportMedicine
Kurogochi K, Stern JA, DeFrancesco TC et al. · 2026 · Journal of the American Veterinary Medical Association
Objective The T-wave peak-end (TpTe) interval and its ratio to the QT interval (TpTe:QT) are ECG markers of myocardial repolarization dispersion. We hypothesized that these markers are associated with echocardiographic indices reflecting…
View details →Negative / Null Result ReportOpen accessMedicine
Eydou Z, Garber S, Sikkema M · 2026 · Cureus
Fusobacterium necrophorum is a recognized cause of brain abscesses and has been classically associated with Lemierre syndrome. We report a case of a 17-year-old male patient who presented with seizures, fever, and altered mental status…
View details →Negative / Null Result Report
Szeto CYY, Kwan HS · 2026 · Preprint
Dietary and lifestyle microbiome interventions often produce mild but heterogeneous remodeling rather than uniform community shifts. In this setting, scalar diversity or group-level summaries can appear weak or inconclusive even when…
View details →Abandoned HypothesisMedicine
Jia W, Yang D, Yu S · 2026 · Computer methods in biomechanics and biomedical engineering
Melasma is a common acquired pigmented dermatosis, which seriously affects the appearance and quality of life of patients. Calreticulin (CALR) is a pleiotropic protein existing in nucleated cells, which mediates cellular immunity, and…
View details →Replication FailureMedicine
Hölscher C · 2026 · Journal of Alzheimer's disease : JAD
BackgroundSemaglutide is a glucagon-like peptide-1 analog that is on the market to treat type 2 diabetes and weight loss (Ozempic, Wegovy). Two phase 3 clinical trials have been conducted, Evoke and Evoke+, testing the drug in patients…
View details →Negative / Null Result ReportOpen accessMedicine
Boualia B, Sandeli A, Boulebd H et al. · 2026 · ACS omega
In this research, we present the successful synthesis of benzimidazolium salts ( 2a - e ) and their corresponding selenium-NHC adducts ( 3a - e ), achieved with satisfactory yields ranging from 75% to 88%, and characterized using…
View details →Negative / Null Result ReportOpen accessMedicine
Qaid MM, Al-Garadi MA, Al-Abdullatif AA et al. · 2026 · Poultry science
Coccidiosis remains a major constraint in poultry production; therefore, this study evaluated the anticoccidial efficacy of a phytogenic blend of cinnamon bark and Rumex nervosus leaf in Eimeria tenella-challenged broilers. Birds were…
View details →Negative / Null Result ReportOpen accessMedicine
Hayashi E, Kano H, Nakamura K et al. · 2026 · Respirology case reports
Small-cell lung cancer (SCLC) has a poor prognosis, and the efficacy of tarlatamab for untreated brain metastases remains unclear. We report a case demonstrating a discrepant response between extracranial and intracranial lesions after…
View details →Negative / Null Result ReportMedicine
Wei X, Xue M, Fan B et al. · 2026 · BMC pulmonary medicine
Background Long-term changes in lung function in children with symptom control asthma are rare. To assess the trajectory of pulmonary function in children and analyze the influence factors. Methods The effects of gender, age, Body Mass…
View details →Negative / Null Result ReportMedicine
Eltahir M, Young K, Younes S et al. · 2026 · American journal of clinical pathology
Objectives Determination of B-cell clonality in formalin-fixed, paraffin-embedded tissues is challenging, especially in cases where tumor B cells are sparse. Flow cytometry is of limited utility in Hodgkin lymphomas, at least in part due…
View details →Negative / Null Result ReportMedicine
Hauck F, Herber V, Moecke S et al. · 2026 · International journal of oral implantology (Berlin, Germany)
Purpose The aim of this pilot preclinical study was to investigate the performance of a novel double-lead thread, conical bone-level ceramic implant manufactured by injection moulding (test group) in comparison to a well-established…
View details →Negative / Null Result ReportMedicine
Uğurlu İ · 2026 · Journal of clinical laboratory analysis
Background Apelin-13 and Galectin-3 (Gal-3) are bioactive mediators linked to inflammation and cardiometabolic pathways. Their clinical utility in COVID-19 alongside routine laboratory tests remains unclear. Methods In this case-control…
View details →Negative / Null Result Report
Yang B, Guo Y, Li J et al. · 2026 · Preprint
Abstract Purpose This study presents the first national-scale assessment of heavy metal contamination, ecological risks, and human health implications in paired park surface dust and soil across 40 Chinese cities over a 15 years period…
View details →Negative / Null Result Report
Rouzic FL, Lacroix J, Ehrmann A et al. · 2026 · Preprint
Abstract Background Several walking tests assess mobility and fall-related function in older adults, but their clinimetric properties remain insufficiently documented across task conditions and assessment environments. Augmented reality…
View details →Negative / Null Result ReportMedicine
Qian MY, He LY, Lan P et al. · 2026 · International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
This study aimed to identify predictors of outcomes and evaluate the therapeutic impact of surgical intervention in CM patients, with a specific focus on the growing HIV-negative population in East Asia. We conducted a single-center…
View details →Negative / Null Result ReportMedicine
Fang H, Feng L, Gu M et al. · 2026 · Personality and mental health
Invalidating family environments are theorized to undermine youths' emotion socialization and confer risk for psychopathology, yet heterogeneity in how invalidation is expressed within families is rarely examined. This study employed…
View details →Negative / Null Result ReportMedicine
Katip A, Demiralp E · 2026 · Toxics
Industrial and domestic wastewaters, nonpoint pollution sources, and climate change affect stream ecosystems, water quantity, and quality. Within the scope of this study, the water quality of Nilüfer Stream was evaluated using the Water…
View details →Negative / Null Result Report
Takashima K, Kawabe T · 2026 · Preprint
The Medusa effect refers to the cognitive phenomenon in which individuals depicted directly in a photograph (Level 1; L1) are judged as possessing more mind than individuals depicted within a photograph embedded inside another photograph…
View details →Negative / Null Result ReportOpen accessMedicine
Bakhshalizadeh S, Mora-Medina R, Ayala-Soldado N · 2026 · Animals : an open access journal from MDPI
Bivalves are widely used in aquatic monitoring, but the potential of their shells to provide comparative metal signatures remains insufficiently explored in the Caspian Sea. This study quantified major and trace elements in empty shells of…
View details →Negative / Null Result ReportMedicine
Alvina, Jaffar H, Onwuzo CN et al. · 2026 · Digestive diseases and sciences
Background Biliary adverse events (AEs) have been reported with glucagon-like peptide-1 receptor agonists (GLP-1RAs), but within-class differences remain unclear. Methods We conducted a disproportionality analysis of FAERS comparing…
View details →Negative / Null Result ReportOpen accessMedicine
Ding J, Li X · 2026 · Biology
Soil depth and habitat degradation can reshape fungal communities in salt-affected wetlands, but their effects on fungal ecological processes remain insufficiently understood. This study examined soil fungi in the Halahai Provincial Nature…
View details →Replication FailureMedicine
Bartusevičius D, Stanislovaitienė J, Conte D · 2026 · Journal of strength and conditioning research
Abstract Bartusevičius, D, Stanislovaitienė, J, and Conte, D. Balancing the game: the relationship of lower-limb asymmetry with youth soccer (football) performance - laboratory vs. field insights. J Strength Cond Res XX(X): 000-000,…
View details →Negative / Null Result ReportMedicine
Zaini AZ, Loganathan T, Danaee M et al. · 2026 · Journal of racial and ethnic health disparities
Background Equitable healthcare access is a key aspect of health equity, yet migrants face substantial barriers. In Malaysia, migrant workers encounter structural and socio-economic barriers to healthcare. Acculturation and social support…
View details →Negative / Null Result ReportMedicine
Nagakura Y, Yamaki F, Saimaru H et al. · 2026 · Currents in pharmacy teaching & learning
Introduction In Japanese pharmacy education, success on the National Pharmacist Examination is a key objective. This study evaluated learning gain across face-to-face, mixed-attendance, and live online participation patterns in a…
View details →Negative / Null Result ReportOpen accessMedicine
Long CY, Chang CY, Sung IC et al. · 2026 · Frontiers in bioengineering and biotechnology
Background Interstitial cystitis (IC) is a disease comprised of multiple symptoms, included persistent bladder pain syndrome (BPS), frequent urination, and urgency without getting infection or other identifiable causes. Methods In our…
View details →Replication FailureMedicine
Ozcan MN, Arisin K, Kefci MM et al. · 2026 · Irish journal of medical science
Background Interest in the use of ChatGPT-4o in scenario-based clinical assessment has increased substantially in recent years. However, studies evaluating ChatGPT-4o in pediatric head trauma scenarios and comparing it with different…
View details →Replication Failure
Quispe Puma MA, Luque-Fernández CR · 2026 · Preprint
Plant-hummingbird interactions are key components of Neotropical ecosystems, yet they remain poorly documented in arid inter-Andean valleys of southern Peru, where floral resources are strongly seasonal. We evaluated the structure,…
View details →Negative / Null Result ReportMedicine
Li L, Wang C, Ji Y et al. · 2026 · Behavioral sciences (Basel, Switzerland)
Previous research suggests receiving a concurrent auditory version of text during reading, i.e., reading-while-listening, improves eye-movement behavior in less skilled readers, while disrupting skilled reading. We extended this approach…
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