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Browse the failure-mode index

21,697 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result Report

Superficial parasternal intercostal plane blocks with liposomal bupivacaine did not significantly reduce opioid use after cardiac surgery: a randomized clinical trial

Eric R Simon, Alysan Mallery, John Silva et al. · 2025 · Regional Anesthesia & Pain Medicine

Background Acute pain after cardiac surgery via median sternotomy is commonly managed with multimodal analgesia, but optimal regional techniques remain uncertain. Superficial parasternal intercostal plane (SPIP) blocks have shown promise…

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Negative / Null Result Report

Partial trailside Japanese barberry (Ranunculales: Berberidaceae) removal did not reduce the abundance of questing blacklegged ticks (Acari: Ixodidae)

Susan P Elias, Peter W Rand, Charles B Lubelczyk et al. · 2024 · Environmental Entomology

Abstract In a nature reserve in southern Maine, we removed invasive Japanese barberry (Berberis thunbergii de Candolle) along sections of forested recreational trails that ran through dense barberry infestations. Barberry thickets provide…

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Failed Experiment Report

Anterior Open‐Wedge Osteotomy to Correct Sagittal and Coronal Malalignment in a Case of Failed High Tibial Osteotomy and Failed Posterior Cruciate Ligament Reconstruction

K. Raghuveer Reddy, N. Somasekhara Reddy, N. Prakash · 2024 · Arthroscopy Techniques

Abstract Anterior open‐wedge high tibial osteotomy of the proximal tibia is a reliable surgical procedure to treat genu recurvatum secondary to decreased posterior tibial slope. It is also useful in cases of posterior cruciate ligament…

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Negative / Null Result Report

Effect of ibuprofen for hemodynamically significant patent ductus arteriosus closure on the development of acute kidney injury in preterm infants

T.P. Borysova, O.Yu. Obolonska · 2021 · Medicni perspektivi (Medical perspectives)

Premature infants with hemodynamically significant patent ductus arteriosus (HSPDA) have a high risk of developing acute kidney injury (AKI) due to renal hypoperfusion and use of ibuprofen for duct closure. The aim of the study was to…

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Negative / Null Result Report

Feature selection by replicate reproducibility and non-redundancy

Tümay Capraz, Wolfgang Huber · 2024 · Bioinformatics

Abstract Motivation A fundamental step in many analyses of high-dimensional data is dimension reduction. Two basic approaches are introduction of new synthetic coordinates and selection of extant features. Advantages of the latter include…

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Negative / Null Result Report

A qualitative process evaluation using the behaviour change wheel approach: Did a whole genome sequence report form ( SRF ) used to reduce nosocomial SARS‐CoV ‐2 within UK hospitals operate as anticipated?

Paul Flowers, Ruth Leiser, Fiona Mapp et al. · 2023 · British Journal of Health Psychology

Abstract Purpose The aim of this study was to conduct a process evaluation of a whole‐genome sequence report form (SRF) used to reduce nosocomial SARS‐CoV‐2 through changing infection prevention and control (IPC) behaviours within the…

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Negative / Null Result Report

Lack of Association between Chlamydophila psittaci and Ocular Adnexal MALT Lymphoma in Korean Patients—Is the Geographic or Genetic Difference Significant?

Uiju Cho, Inju Cho, Sung Hak Lee et al. · 2021 · Diagnostics

Clamydophila psittaci (C. psittaci) has been proposed to be an etiologic factor in extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) in the ocular adnexa. However, the pathogenetical significance of the…

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Negative / Null Result Report

No significant post‐operative limb length difference following medial opening wedge high tibial osteotomy in a multi‐ethnic Southeast Asian population

Brjan Kaiji Betzler, Sandip Singh Saggi, Matthias Yi Quan Liau et al. · 2023 · Journal of Experimental Orthopaedics

Abstract Purpose This study aims to assess the significance of post‐operative change in limb length in medial opening wedge high tibial osteotomy (MOWHTO), and evaluate the correlation between correction angles and changes in limb length.…

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Negative / Null Result Report

Fellow Efficiency During Anterior Cruciate Ligament Reconstruction Improves Over Time, Yet Is Less Than Experienced Physician Assistant But With No Significant Difference in Patient‐Reported Outcomes

Sean M. Hazzard, Donna M. Scarborough, Eric M. Berkson et al. · 2022 · Arthroscopy, Sports Medicine, and Rehabilitation

Purpose To evaluate the intraoperative efficiency and patient outcomes of anterior cruciate ligament reconstruction (ACLR) assisted by a sports medicine fellow over the course of the academic year compared with an experienced physician…

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Negative / Null Result Report

Significant difference in gut microbiota Bifidobacterium species but not Lactobacillus species in colorectal cancer patients in comparison with healthy volunteers using quantitative real-time PCR

Fahime Esfandiari, Bita Bakhshi, Tayebe Shahbazi et al. · 2024 · PLOS ONE

Background Colorectal cancer (CRC), with a growing incidence trend, is one of the most diagnosed cancers and the second cause of cancer-related deaths worldwide. The literature has frequently focused attention on the correlation between…

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Negative / Null Result Report

How Statistically Significant is the DMCA Coefficient?

Everaldo Freitas Guedes · 2021 · Fluctuation and Noise Letters

In this paper, we proposed a statistical test for the Detrending Moving-Average Cross-Correlation Coefficient ([Formula: see text]). With this methodology, it is possible to evaluate the statistical significance of [Formula: see text] for…

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Negative / Null Result Report

MENGINTEGRASIKAN TEKNOLOGI DIGITAL DALAM PEMBELAJARAN DI MI/SD PADA ERA REVOLUSI INDUSTRI 5.0

Shinta April Lailia, Siti Fatimah, Afil Fres Seftiana et al. · 2023 · SIGNIFICANT : Journal Of Research And Multidisciplinary

Penelitian ini bertujuan untuk mengeksplorasi media dan metode yang tepat dalam penerapan teknologi digital di sekolah-sekolah dengan fokus pada pendidikan MI/SD. Beberapa contoh media yang mendukung seperti Quizizz, Wordwall, Zoom, dan…

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Negative / Null Result Report

Nocturnal Emissions: A Failure to Replicate

Keith F. Widaman, Jonathan L. Helm · 2012 · The American Journal of Psychology

Abstract A time series of nocturnal emissions was presented in The American Journal of Psychology in 1904. The anonymous author of this remarkable article provided the time series to support his contention that his nocturnal emissions…

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Negative / Null Result Report

Social role effects on English particle verb variation fail to replicate

Naomi Lee, Laurel Mackenzie · 2023 · Canadian Journal of Linguistics/Revue canadienne de linguistique

Abstract The English particle verb alternation has been argued to be sensitive to the social role occupied by speakers on radio broadcasts; Kroch and Small (1978) argue that radio show hosts and in-studio guests’ greater sensitivity to…

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Negative / Null Result Report

Significant difference in Miscanthus species root carbon exudation rate

Amanda J Holder, Rebecca Wilson, Karen Askew et al. · 2025 · Annals of Botany

Abstract Background and Aims The cultivation of Miscanthus, a giant perennial grass and promising biomass crop, is expected to increase globally in response to climate mitigation policies and sustainable agriculture goals. Little is known…

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