Superficial parasternal intercostal plane blocks with liposomal bupivacaine did not significantly reduce opioid use after cardiac surgery: a randomized clinical trial
Eric R Simon; Alysan Mallery; John Silva; Andreas de Biasi; Satoru Osaki; Bryan M Krause; Patrick Meyer · 2025 · Regional Anesthesia & Pain Medicine
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Background Acute pain after cardiac surgery via median sternotomy is commonly managed with multimodal analgesia, but optimal regional techniques remain uncertain. Superficial parasternal intercostal plane (SPIP) blocks have shown promise…
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Metadata source: Crossref · DOI 10.1136/rapm-2025-106952