Negative / Null Result ReportOpen accessEngineering
H. Fu, Xiong Zhou, Pengfei Xu et al. · 2025 · Materials
Predicting the compressive strength of concrete is essential for engineering design and quality assurance. Traditional empirical formulas often fall short in capturing complex multi-factor interactions and nonlinear relationships. This study employs an interpretable machine learning framework using Gradient Boosting Trees, Random Forest, and Backpropagation Neural Networks to predict concrete compressive strength. Bayesian optimization was employed for hyperparameter tuning, and SHAP analysis was used to quantify feature contributions. Based on 223 sets of compression test data, this study sys
View details →Negative / Null Result ReportOpen accessChemistry
Tongbo Zhu, Zhiying Wang, Lynn M. McMullen et al. · 2021 · Microorganisms
The locus of heat resistance (LHR) confers resistance to extreme heat, chlorine and oxidative stress in Escherichia coli. This study aimed to determine the function of the LHR in maintaining bacterial cell envelope homeostasis, the regulation of the genes comprising the LHR and the contribution of the LHR to alkaline pH response. The presence of the LHR did not affect the activity of the Cpx two-component regulatory system in E. coli, which was measured to quantify cell envelope stress. The LHR did not alter E. coli MG1655 growth rate in the range of pH 6.9 to 9.2. However, RT-qPCR results ind
View details →Negative / Null Result ReportOpen accessAgricultural and Biological Sciences
Wenying Huo, Yingying Qiao, Xiangru He et al. · 2025 · Toxins
Mycotoxins are toxic secondary metabolites produced by filamentous fungi that contaminate agricultural commodities, posing risks to food safety, animal productivity, and human health. The gastrointestinal tract is the first and most critical site of exposure, where the intestinal epithelium functions as both a physical and immunological barrier against luminal toxins and pathogens. While extensive research has demonstrated that mycotoxins disrupt epithelial integrity through tight junction impairment, oxidative stress, apoptosis, and inflammation, their effects on the intestinal stem cell (ISC
View details →Negative / Null Result ReportMedicine
Maximilian Stahl, Amer M. Zeidan · 2025 · Blood
ABSTRACT: Aside from allogeneic transplantation, the current standard-of-care approach for higher-risk myelodysplastic syndromes/neoplasms (HR-MDS) remains monotherapy with a hypomethylating agent (HMA), including azacitidine, decitabine,…
View details →Negative / Null Result ReportOpen accessMedicine
Sathish Babu Vasamsetti, Samreen Sadaf, Mohammad A. Uddin et al. · 2026 · Nature Communications
How cellular metabolism facilitates tissue-resident macrophage maintenance remains elusive. Here we show that visceral adipose tissue (VAT)-resident macrophages, unlike monocyte-derived macrophages, are enriched with mitochondrial-specific antioxidant enzymes restraining inflammation and promoting VAT homeostasis and insulin sensitivity. Additionally, VAT resident macrophages express high levels of plasminogen activator inhibitor type 2, encoded by SerpinB2, which is involved in the blood coagulation cascade. SerpinB2 promotes adipose resident macrophage survival by regulating mitochondrial ox
View details →Negative / Null Result ReportOpen accessEngineering
Cao Zhengzheng, Guo Fangxu, Rong Tao et al. · 2026 · Scientific Reports
Floor aquifers are responsible for approximately 55% of water inrush incidents in coal mines. As mining depths increase, the risk posed by confined floor aquifers becomes more severe. Grouting reinforcement and the sealing of water…
View details →Negative / Null Result ReportOpen accessDentistry
Chen Ding, Dize Li, Linzhu Su et al. · 2026 · International Journal of Oral Science
Nanotechnology has provided thousands of novel nano-antimicrobials possessing features uncommon in clinically available antimicrobials. Here, nanocarriers loaded with conventional antimicrobials and responding to environmental changes upon…
View details →Negative / Null Result ReportOpen accessEngineering
Bin Liu, Changfeng Yan, Ming Lv et al. · 2026 · Computers in Industry
Domain adaptation-based methods are extensively applied to predict the Remaining Useful Life (RUL) of rolling bearings under complex operating conditions. However, the nonlinear degradation process of bearings gives rise to markedly…
View details →Negative / Null Result ReportOpen accessPhysics and Astronomy
R. Abbasi, M. Ackermann, J. Adams et al. · 2026 · The Astrophysical Journal Letters
Abstract Recently, IceCube reported neutrino emission from the Seyfert galaxy NGC 1068. Using 13.1 yr of IceCube data, we present a follow-up search for neutrino sources in the northern sky. NGC 1068 remains the most significant neutrino source among 110 preselected gamma-ray emitters while also being spatially compatible with the most significant location in the northern sky. Its energy spectrum is characterized by an unbroken power-law with spectral index γ = 3.4 ± 0.2. Consistent with previous results, the observed neutrino flux exceeds its gamma-ray counterpart by at least 2 orders of magn
View details →Negative / Null Result ReportOpen accessMedicine
Qi Sun, Yanping Zhao, Simiao Qiao et al. · 2026 · Nature Communications
Radiotherapy can both activate and suppress immunity, making it difficult to predict or modulate these opposing effects for better cancer treatment. Boron neutron capture therapy (BNCT), a cellular-level radiotherapy, has demonstrated…
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P. Sumithran, K. Purcell, S. Kuyruk et al. · 2017 · Clinical Obesity
Summary Consistent, strong predictors of obesity treatment outcomes have not been identified. It has been suggested that broadening the range of predictor variables examined may be valuable. We explored methods to predict outcomes of a…
View details →Negative / Null Result Report
Richard A. Gallenstein, John P. Dougherty · 2024 · American Journal of Agricultural Economics
Abstract Index insurance programs in developing countries have focused almost entirely on agricultural production risk (i.e., yield) while largely avoiding output marketing risk (i.e., price). This omission may miss an important constraint…
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Guangming Chen, Xiaoyun Shan, Huabin Wang · 2021 · Nephrology
Abstract Aim Various studies have reported that urinary neutrophil gelatinase‐associated lipocalin (NGAL), an indicator of tubular damage, may be an effective biomarker of renal impairment in patients with diabetes. This study aimed to…
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Jason West, Maiko Chu, Lincoln Crooks et al. · 2018 · Journal of Business Strategy
Purpose Business wargames represent an alternative approach to challenge organisations to uncover internal capabilities through competitive actions designed to counteract external threats and address strategic mismatches. Internal…
View details →Negative / Null Result Report
Dolores Ruiz-Lupión, Jordi Pascual, Nereida Melguizo-Ruiz et al. · 2019 · Insects
Soil fauna play a key role in nutrient cycling and decomposition, and in recent years, researchers have become more and more interested in this compartment of terrestrial ecosystems. In addition, soil fauna can act as ecosystem engineers…
View details →Negative / Null Result Report
Natsu Sasaki, Reiko Kuroda, Kanami Tsuno et al. · 2022 · Neuropsychopharmacology Reports
Abstract Objectives This study aimed to examine the effectiveness of vaccination to improve mental health among employees in Japan based on a prospective study. Methods The data were retrieved from the Employee Cohort Study conducted…
View details →Negative / Null Result Report
Anna Adamczak-Bugno, Aleksandra Krampikowska · 2020 · Materials
This article proposes to use the acoustic emission (AE) method to evaluate the degree of change in the mechanical parameters of fiber–cement boards. The research was undertaken after a literature review, due to the lack of a methodology…
View details →Negative / Null Result Report
Gengsheng L. Zeng · 2012 · International Journal of Imaging Systems and Technology
Abstract The iterative maximum‐likelihood expectation‐maximization (ML‐EM) algorithm is an excellent algorithm for image reconstruction and usually provides better images than the filtered backprojection (FBP) algorithm. However, a…
View details →Negative / Null Result Report
Jack W. O’Sullivan, John P. A. Ioannidis · 2021 · Scientific Reports
Abstract With the establishment of large biobanks, discovery of single nucleotide variants (SNVs, also known as single nucleotide polymorphisms (SNVs)) associated with various phenotypes has accelerated. An open question is whether…
View details →Negative / Null Result Report
Yui Matsuda, Todd A. Schwartz, YunKyung Chang et al. · 2019 · Journal of the American Psychiatric Nurses Association
BACKGROUND: Mothers’ depressive symptoms affect their children’s growth as well as physical and mental well-being. Moreover, mothers of young children with developmental delay or disability (DD) tend to have higher depressive symptoms.…
View details →Negative / Null Result Report
Mona Almalik, Alice Kiger, Janet Tucker · 2010 · International Journal of Qualitative Methods
Although a few researchers mention that involving interpreters can have an impact on the research process and research findings, little is published regarding methods of assessing the interpretation work's quality and impact. The impact of…
View details →Negative / Null Result Report
Peter N. Chalmers · 2019 · Arthroscopy
Abstract The optimal surgical technique for arthroscopic rotator cuff repair remains controversial, with advantages and disadvantages to each of the most commonly used methods. The pattern as well as number of suture anchors relative to…
View details →Negative / Null Result Report
Gordon Minru Xiong, Kailash Venkatraman, Subbu Venkatraman · 2020 · Progress in Biomedical Engineering
Abstract Ever since the term ‘Magic Bullet’ was coined by Nobel laureate Paul Ehrlich to denote selective activity of a therapeutic medicine against a particular target tissue or organism, researchers have been attempting to develop the…
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Nicholas Smith, Kathleen F. Hunter, Saima Rajabali et al. · 2019 · Journal of Wound, Ostomy & Continence Nursing
PURPOSE: This study aimed to determine from what sources women with urinary and dual urinary and fecal incontinence sought and received information about incontinence and absorbent products. We also evaluated source utility. DESIGN:…
View details →Negative / Null Result Report
Yuriko Adkins, Kevin D. Laugero, Bruce Mackey et al. · 2019 · Lipids
Abstract Recent studies suggest that dietary krill oil leads to higher omega‐3 polyunsaturated fatty acids (n‐3 PUFA) tissue accretion compared to fish oil because the former is rich in n‐3 PUFA esterified as phospholipids (PL), while n‐3…
View details →Negative / Null Result Report
Thomas Gerhard Wolf, Elena Baumgärtner, Burkhard Peter · 2022 · Frontiers in Psychology
Several publications with healthcare professionals, such as psychotherapists, have shown a significant difference in personality styles in practitioners using hypnosis compared to those not using hypnosis. To investigate differences in…
View details →Negative / Null Result Report
Rolando A. Rebolledo, Bo Liu, Mohammed Z. Akhtar et al. · 2015 · BioMed Research International
Effect of glucocorticoid administration on improving the outcomes of kidney and liver allografts has not been clearly elucidated. This study investigated the effect of prednisolone administration after onset of brain death (BD) on kidney…
View details →Negative / Null Result ReportOpen accessMedicine
Hisayuki Katsuyama, Hidekatsu Yanai, Hiroki Adachi et al. · 2023 · Gastroenterology Research
Background: We previously reported that the selective peroxisome proliferator-activated receptor alpha modulator, pemafibrate, significantly reduced serum levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT) and…
View details →Negative / Null Result Report
Mattias Ekre, Jakob Tytor, Mogens Bove et al. · 2020 · Diseases of the Esophagus
Summary Eosinophilic esophagitis (EoE) is a chronic inflammatory condition with eosinophilic infiltration of the esophageal mucosa. The most prominent symptom is dysphagia, which may result in esophageal bolus impaction in need of surgical…
View details →Negative / Null Result ReportOpen accessEngineering
Joao Gabriel Ostrowski, József Menyhárt · 2020 · Acta Polytechnica Hungarica
Based particularly on data technologies, information is rapidly evolving in engineering. In mechanical engineering, maintenance is benefiting the most from data innovations, the reduction of maintenance costs, and the improvement of system…
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