Contribution of the Locus of Heat Resistance to Growth and Survival of Escherichia coli at Alkaline pH and at Alkaline pH in the Presence of Chlorine
Tongbo Zhu; Zhiying Wang; Lynn M. McMullen; Tracy Raivio; David J. Simpson; Michael G. Gänzle · 2021 · Microorganisms
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
The finding, in one line
“The presence of the LHR did not affect the activity of the Cpx two-component regulatory system in E.”
Abstract
The locus of heat resistance (LHR) confers resistance to extreme heat, chlorine and oxidative stress in Escherichia coli. This study aimed to determine the function of the LHR in maintaining bacterial cell envelope homeostasis, the regulation of the genes comprising the LHR and the contribution of the LHR to alkaline pH response. The presence of the LHR did not affect the activity of the Cpx two-component regulatory system in E. coli, which was measured to quantify cell envelope stress. The LHR did not alter E. coli MG1655 growth rate in the range of pH 6.9 to 9.2. However, RT-qPCR results ind
Abstract by Tongbo Zhu; Zhiying Wang; Lynn M. McMullen; Tracy Raivio; David J. Simpson; Michael G. Gänzle, Microorganisms (2021) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.3390/microorganisms9040701