21,770 real negative results, null findings, and replication failures. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Marcoux V, Mondal P, Adegunsoye A et al. · 2025 · ERJ open research
Background The impact of applying different lung function reference equations and interpretation methods in fibrotic interstitial lung disease (ILD) is poorly understood. We aimed to evaluate disease severity classification, trajectories…
View details →Längle A, Reyes Del Paso GA, Ettinger U et al. · 2025 · Psychophysiology
Adult attention-deficit/hyperactivity disorder (ADHD) is associated with substantial impairments in well-being and quality of life. In addition to cognitive and behavioral symptoms, emotional dysregulation characterizes the disorder. This…
View details →Neenan A, Byrd M · 2026 · Journal of psychosocial oncology
Background There are nearly 500,000 childhood cancer survivors in the United States, and emerging evidence suggests at least 25% of these survivors have lost a peer to cancer. The current study investigated the nature of peer loss in a…
View details →Houghton JSM, Black I, Meffen A et al. · 2026 · Annals of vascular surgery
Background The wound, ischemia and foot infection (WIfI) classification system has been widely adopted in chronic limb-threatening ischemia (CLTI) management. Primary aim was to prospectively investigate the association of WIfI stage with…
View details →Androvičová R, Jahn K, Engel J et al. · 2026 · Behavioural brain research
Rationale The compulsive sexual behaviour disorder (CSBD) is a recent addition to the ICD-11 diagnostic manual under the chapter of impulse control disorders. Though there is a wealth of different theoretical viewpoints regarding the…
View details →Wang F, Wang C, Wang T et al. · 2025 · Preprint
Genotype-phenotype associations can be context-dependent and dynamic in nature leading to heterogeneity of genetic effects across different parts of the phenotype distribution. Quantile regression, an alternative to linear regression for…
View details →Xiang H, Lin C, Chen S et al. · 2025 · Current HIV research
Introduction Peripheral blood lymphocyte subsets have been shown to influence prognosis in HIV-associated Diffuse Large B-Cell Lymphoma (HIV-DLBCL), a rare and highly aggressive form of non-Hodgkin's lymphoma linked to immunosuppression…
View details →Bitran AM, Kleiman EM, Rizvi SL · 2026 · Archives of suicide research : official journal of the International Academy for Suicide Research
Objective Suicidal communications (SCs)-also known as suicide threats or "gestures," whereby an individual verbally or behaviorally signals suicidal intent-present a serious challenge to clinicians and loved ones, who may struggle to…
View details →Mehta R, Sah R · 2025 · Cerebral circulation - cognition and behavior
•SDMT drop at baseline linked to higher Fazekas (WMH) scores.•No follow-up MoCA/SDMT association after multiple correction.•Practice effects likely inflated cognitive test recovery scores.•High attrition biased against fatigue and…
View details →Liampas I, Tsirelis D, Dastamani M et al. · 2024 · Journal of molecular neuroscience : MN
Background and objectives Data on the association between BDNF rs6265 and multiple sclerosis (MS) are scarce and heterogeneous. Materials and methods We undertook a case-control study design. Newly diagnosed individuals with MS based on…
View details →Yin Q, Shu T, Chen Z et al. · 2025 · Preprint
Abstract Background To investigate the relationship between emotional dysregulation, as measured by the emotional go/nogo task, and the multidimensional profile of borderline personality disorder (BPD). Methods Eighty-two participants (32…
View details →Ajam G, Daryabor G, Jazi NN et al. · 2025 · Preprint
Abstract Viruses are among the most infectious agents thought to contribute to the development of autoimmune disorders. Adenoviruses, in particular, are widely utilized for various applications, including gene therapy, vaccine vectors, and…
View details →Heasley CK, Stefanova V, Funk C et al. · 2025 · Preprint
Background Bifidobacterium longum subspecies infantis ( B. infantis ) abundance in the infant gut may be associated with growth and health outcomes. However, these relationships have not been widely studied in settings where B. infantis is…
View details →Miceli MH, Dalton LM, Pasqualotto AC et al. · 2025 · Open Forum Infectious Diseases
Background Histoplasma urine antigen detection, a valuable diagnostic tool, is often used to monitor response to antifungal therapy, but persistently positive antigen values, even when the infection has resolved, often present a clinical…
View details →Lin X, Ou J, Wu G et al. · 2025 · Biochemistry and biophysics reports
Introduction Venous malformations are the most common congenital vascular anomaly, accounting for 65 % of all congenital vascular abnormalities. This study aims to investigate the correlation between genetic polymorphisms of MALAT1 and the…
View details →Ma Y, Mayes MD, Guo X et al. · 2024 · Preprint
Abstract Objective This study aimed to examine whether a reported SSc-associated SNP rs2841277 in the PLD4 gene identified in an Asian population was also associated with SSc in US Caucasians. Methods The US Caucasian cohort consisting of…
View details →Velaga SB, Alagorie AR, Nittala MG et al. · 2025 · Ophthalmology science
Purpose To evaluate the change in the area of reticular pseudodrusen (RPD) and choroidal thickness over 2 years in eyes with age-related macular degeneration (AMD). Design Longitudinal cohort study. Subjects The study reviewed 1332 eyes…
View details →Belica I, Blasko F, Sleziak I et al. · 2025 · Biological psychology
Resting heart rate variability (HRV) reflects rhythmic changes in heart rate over time associated with autonomic nervous system (ANS) activity. It has served as a predictor of health and the development of various diseases. Therefore, it…
View details →Govender V, Govender K, Moodley D · 2026 · BMC infectious diseases
BACKGROUND: Maintaining viral suppression in the postpartum period is critical for preventing HIV transmission to sexual partners and breastfed infants. Despite systemic viral suppression, genital HIV shedding may still occur in some…
View details →Kambara M, Ikawa F, Hidaka T et al. · 2025 · Neurosurgery
Background and objectives Some reports suggest that older patients with traumatic brain injury (TBI) are more likely to experience acute intracranial hemorrhage, resulting in poor outcomes. However, the association between precise…
View details →Rodriguez JA, Palermo NE, Song W et al. · 2026 · Diabetes technology & therapeutics
Continuous glucose monitors (CGMs) are becoming increasingly available, yet the relationship between CGM metrics and hemoglobin A1c (HbA1c) among individuals with prediabetes and normoglycemia remains unclear. We examined associations…
View details →de Luis D, Primo D, Izaola O et al. · 2024 · European review for medical and pharmacological sciences
Objective Sarcopenia is a condition characterized by muscle mass loss. Skeletal muscle is capable of producing and secreting different molecules called myokines, and apelin is one of them. The literature contains contradictory data on the…
View details →Leibold P, Lteif C, Duarte JD · 2025 · Frontiers in genetics
Introduction Hypertension (HTN) is a leading risk factor for several cardiovascular diseases. While some previous studies reported that CYP3A5 variants were associated with decreased blood pressure and risk of HTN, others reported no…
View details →Solanki JD, Joshi DR, Atodaria KA et al. · 2025 · Journal of family medicine and primary care
Introduction Cardiovascular health is adversely affected by menopausal transition with reduced heart rate variability (HRV) as a manifest. Electrocardiogram (ECG) based 5 min HRV has worsening trend from premenopausal to postmenopausal…
View details →McHenry MS, Huo Y, Williams PL et al. · 2026 · Journal of acquired immune deficiency syndromes (1999)
Background Our objective was to evaluate the association between inflammatory biomarkers and NIH Toolbox cognitive outcomes in young adults with perinatal HIV exposure but uninfected (YAPHEU) and those with perinatal HIV (YAPHIV), with or…
View details →Bontrager M, Worthy SJ, Leventhal L et al. · 2025 · Preprint
Summary Herbarium specimens are broadly distributed in space and time, enabling investigation of climate impacts on phenology and fitness. We reconstructed specimen “lived” climate from knowledge of germination cues and collection dates…
View details →Hunter JWS, Van Den Heuvel C, Stephenson L et al. · 2025 · The American journal of forensic medicine and pathology
Abstract Both obesity and opioid abuse are increasing in numbers globally. As these entities may be associated with significant respiratory compromise, it was hypothesized that synergism may occur and that as a result of this obese…
View details →Christian K, Moritz C, Skelton K et al. · 2024 · Preprint
1. Reptiles are challenged with maintaining stable hydric states and viable body temperatures in a variable terrestrial environment. Reptiles can use behaviour to select favourable microhabitats as well as physiological adaptations, such…
View details →Eskandarian S, Zafarani A, Tandel P et al. · 2025 · Molecular biology reports
Background Clopidogrel is a widely used antiplatelet drug for treating acute coronary syndrome. Its metabolism primarily involves the CYP2C19 isoenzyme, with CYP2C192 and CYP2C193 alleles associated with reduced metabolic activity.…
View details →Dias ALB, Nascimento JR, Brito-Sousa JD et al. · 2025 · PloS one
Background Glucose-6-phosphate dehydrogenase deficiency (G6PDd) is a common genetic disorder that impairs the cellular antioxidant response and has been hypothesized as a potential risk factor for severe outcomes in viral infections,…
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