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Browse the failure-mode index

21,770 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Questionable indication for postoperative radiotherapy after surgery for metastases of the major long bones: A single-centre cohort study of 552 fractures/526 patients.

Ehne, Kastensson, Wedin et al. · 2026 · Journal of bone oncology

The use of postoperative radiotherapy (PORT) as an adjunct to orthopaedic surgery of the long bones is widely recommended. Evidence of the benefits is however sparse. The primary research question of this study was whether PORT reduces the…

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Negative / Null Result ReportMedicine

Trends and predictors of caesarean section in Thailand before and during the COVID-19 pandemic: a retrospective analysis of national hospitalisation data under the Universal Coverage Scheme.

Karunayawong, Sukmanee, Butchon et al. · 2026 · BMJ open

Since 1985, the international healthcare community has recommended the ideal rate of caesarean section (CS) to be 10%-15% at the national level. The literature has reported that overused CS without necessary medical indications can be…

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Abandoned HypothesisMedicine

Two New Pyrrole Alkaloids From Lanmaoa asiatica.

Li, Hou, Li et al. · 2026 · Chemistry & biodiversity

Two new pyrrole alkaloids, asiaticain A (1) and asiaticain B (2), two aromatic compounds 3-4, and one steroid 5 were isolated from Lanmaoa asiatica. The structural elucidation of the isolated compounds was determined by using NMR, MS, IR,…

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Negative / Null Result ReportMedicine

Evaluation of bone repair using sticky bone in preradiotherapy extraction sockets of head and neck cancer patients: a pre- and postradiotherapy follow-up.

Rodrigues, Macedo, de Paulo et al. · 2026 · Oral surgery, oral medicine, oral pathology and oral radiology

To evaluate the effects of sticky bone a biomaterial composed of Solid-PRF (S-PRF), a variant of platelet-rich fibrin (PRF), and deproteinized bovine bone-on bone formation after tooth extraction performed prior to radiotherapy, with…

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Failed Experiment ReportMedicine

Early onset radiation-induced leukoencephalopathy in patients treated for a glioblastoma by STUPP protocol and risk factors evaluation, an ancillary study of the phase III ASTER protocol.

Balcerac, Cuzzubbo, Bompaire et al. · 2026 · Revue neurologique

Since 2005, the standard treatment for newly diagnosed glioblastoma involves radiotherapy combined with concomitant and adjuvant temozolomide (TMZ), as per the Stupp protocol. A known long-term complication of radiotherapy is…

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Negative / Null Result ReportMedicine

Sleep and Haemophilia-A Case-Control Analysis of Associated Factors.

Schmidt, Brühl, Möllers et al. · 2026 · Haemophilia : the official journal of the World Federation of Hemophilia

Sufficient sleep is essential for maintaining both physical and mental health, yet data on sleep health among persons with haemophilia (PwH) remain limited. This study aimed to assess sleep in PwH compared to healthy controls (Con) and…

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Negative / Null Result ReportMedicine

Impact of the platelet storage time on transfusion-related adverse reactions: A French hemovigilance study.

Pires Marafon, Reuter, Isola et al. · 2026 · Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine

The legal shelf life of platelet concentrates (PCs) has been extended from 5 to 7 days in France since 2018. Our study aimed to determine whether this increase in PC storage time has produced a significant impact on…

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