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Browse the failure-mode index

21,770 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Spectroscopic analysis of the N<sub>2</sub> B<sup>3</sup>Π<sub>g</sub>-A<sup>3</sup>Σ+u in radiation-induced air ionization.

Murzyn CM, Jans ER, Marshall GJ · 2026 · Physical chemistry chemical physics : PCCP

This article presents experimental results from probing atmospheric air irradiated by a Polonium-210 alpha particle source using both optical emission spectroscopy and continuous wave cavity ring down absorption spectroscopy to study the…

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Negative / Null Result Report

Assessing Brain-Behaviour Coupling in Non-invasive Brain Stimulation Using Reliable Change Indices: Evidence from pre-Supplementary Motor Area – right Inferior Frontal Gyrus transcranial Alternating Current Stimulation

Fujiyama H, Wansbrough K, Lebihan B et al. · 2026 · Preprint

Non-invasive brain stimulation (NiBS) studies frequently report exploratory correlations between individual-level changes in neurophysiological and behavioural measures. However, these analyses are typically underpowered and rely on…

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Negative / Null Result Report

Geomagnetic Excursions as CO₂-Null Climate Forcing Events: The Laschamps/Adams Event in Proxy Context and a Comparative Analysis of Brunhes Chron Excursions Against the EPICA Dome C Record

Gray JH · 2026 · Preprint

The Laschamps geomagnetic excursion (~41-42 ka BP) represents the largest geomagnetic field collapse in the past 800,000 years, driving documented megafaunal extinctions, Neanderthal extinction, Northern Hemisphere ice sheet expansion, and…

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Negative / Null Result ReportOpen accessMedicine

Gender Differences in Preoperative Anxiety and the Association with Early Maladaptive Schemas: A Cross-Sectional Correlational Study.

Abdelrazek MN, Mohamed HMM, El-Monshed AH et al. · 2026 · Healthcare (Basel, Switzerland)

Background : Preoperative anxiety is a common and clinically significant response among surgical patients, with prevalence estimates ranging from 30% to over 80% depending on measurement method and surgical context. Early maladaptive…

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Negative / Null Result ReportOpen accessMedicine

Safety of hepatitis E vaccine in pregnancy.

Zhang F, Yang G, Chen Y et al. · 2026 · Virology journal

This comment discusses the critical public health challenge of hepatitis E in pregnancy and highlights the significant safety evidence gap for the HEV239 vaccine in this vulnerable group. Focusing on a landmark study from South Sudan by…

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Negative / Null Result ReportMedicine

Overnight residues of sensorimotor aftereffects and lack of visuospatial aftereffects following a single prism exposure in healthy subjects.

Mizrahi O, Wilf M, Ovadia-Caro S · 2025 · Cortex; a journal devoted to the study of the nervous system and behavior

Prism adaptation (PA) is a visuomotor adaptation paradigm resulting in transient sensorimotor shifts. Previous work shows PA can cause additional changes in higher-level visuospatial representations in healthy subjects. In patients with…

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Negative / Null Result ReportOpen accessMedicine

Biological Therapy Leads to a Reduction in Systemic Inflammation but Leaves Serum Uric Acid Unmodified in Moderate-to-Severe Plaque Psoriasis: A Prospective Longitudinal Cohort Study.

Suiu LI, Vreju FA, Turcu-Stiolica A et al. · 2026 · Journal of clinical medicine

Background/Objective: Psoriasis is a systemic inflammatory disease often associated with metabolic comorbidities, including hyperuricemia. While biological therapies effectively target inflammatory pathways, their specific impact on serum…

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Negative / Null Result ReportOpen accessMedicine

Are Atrial Fibrillation Risk Loci Universally Applicable? Insights from Whole-Genome Sequencing in a Polish Population.

Wasiak M, Sypniewski M, Dobosz P et al. · 2026 · Medical sciences (Basel, Switzerland)

Background: Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia worldwide and has a substantial genetic component. Genome-wide association studies (GWASs) have identified more than 100 susceptibility loci; however,…

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Negative / Null Result Report

Fallacy of the Absolute Speed of Light

Hajra S · 2024 · Preprint

In this article, we have rationally analyzed the null result of the Michelson-Morley experiment, along with the unique observation that all electrodynamic phenomena, whether terrestrial, solar, or astral, are independent of the motion of…

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Negative / Null Result ReportOpen accessMedicine

Does Provider Identity at Triage Improve Machine Learning Prediction of Hospital Admission? A Comparative Analysis of Ten Supervised Classifiers with SHAP Explainability.

Brown AE, Marostica CW, Martini WA · 2026 · Journal of personalized medicine

Background/Objectives: Machine learning (ML) models can predict hospital admission from emergency department (ED) triage data with areas under the receiver operating characteristic curve (AUC) exceeding 0.85. Whether incorporating the…

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Negative / Null Result ReportOpen accessMedicine

The Question of Violent Video Games and Aggression: Testing Statistical and Methodological Issues of Null Effects Using Data From an Open-Access Case Study.

Miles-Novelo A, Anderson CA · 2025 · Aggressive behavior

While numerous meta-analyses, reviews, and task forces from various scientific bodies have linked violent media use to aggression, some studies report null effects and claim that such a relationship is non-existent. Several scholars have…

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Negative / Null Result ReportOpen accessMedicine

FreeSurfer-Based MRI Volumetry Reveals Thalamic and Hippocampal Atrophy as Significant Correlates of Disability in Multiple Sclerosis.

Juković M, Stošić S, Kostić D et al. · 2026 · Medicina (Kaunas, Lithuania)

Background and Objectives : Multiple sclerosis (MS) is a chronic inflammatory and neurodegenerative disease that progressively leads to brain atrophy and the accumulation of disability over time. In this study, we used FreeSurfer to…

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Negative / Null Result ReportOpen accessMedicine

Economic incentives contribute little to reducing agricultural damage from invasive non-native species: evidence from raccoon management in Hokkaido, Japan.

Mameno K, Suzuki T, Yamaguchi S et al. · 2026 · Pest management science

Background An economic incentive scheme is utilized to enhance citizens' support for managing invasive non-native species. However, the effectiveness of the incentive scheme in the outcomes of the management remains unclear. This study…

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