21,770 real negative results, null findings, and replication failures. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Jhaveri k, Mai N, Anjos CHd et al. · 2024 · Preprint
Abstract After disease progression on endocrine therapy (ET) plus a CDK4/6 inhibitor, there is no standardized sequence for subsequent treatment lines for estrogen receptor positive (ER+) metastatic breast cancer (MBC). CDK4/6i retrial as…
View details →Needle R, Yu Y, Soualhine H et al. · 2025 · Biomedicines
Background/Objectives : The diagnosis of Mycobacterium tuberculosis complex (MTBC) and nontuberculous mycobacterial (NTM) infections is accomplished by three main diagnostics methods: smear microscopy, culture, and molecular testing.…
View details →Kirby C, Baldwin JA, Elwell K et al. · 2026 · Healthcare (Basel, Switzerland)
Background The literature shows inconclusive results from utilizing motivational interviewing (MI) in indigenous populations to address early childhood caries (ECC). Great Beginnings for Healthy Native Smiles (GBHNS) (NIDCR U01DE028508), a…
View details →Fan J, Zeng F, Zhong H et al. · 2024 · Preprint
Abstract Cigarette smoking is posited as a potential factor in disrupting the balance of the human gut microbiota. However, existing studies with limited sample size have yielded inconclusive results. Here, we assessed the association…
View details →Reis da Silva T · 2024 · British journal of community nursing
Aim This study reviews research into the effects of the supplementation of B12 in the prevention and recovery of mental illness, and the potentiation of psychotropic medication. Methodology This literature review follows a systematic…
View details →Zhang Y, Baharani J, Ajayi B et al. · 2025 · BMC nephrology
Background Fibrillary glomerulonephritis (FGN) is a rare immune complex-mediated glomerulonephritis characterised by the deposition of anomalous fibrillary structures within the glomeruli. The prognosis for patients with FGN is usually…
View details →Gobishangar S, Abiharan P, Jenil A et al. · 2026 · Cureus
Background The appendix is a vermiform structure with a variable position, length, and thickness. Imaging plays a critical role in diagnosing an inflamed appendix, with non-contrast computed tomography (NCCT) being an effective modality…
View details →Bronkhorst H, Kalaykova S, Huysmans MC et al. · 2024 · Journal of dentistry
Objective This study presents a scoping review to determine the association between tooth wear and bruxism. Data A protocol was developed a priori (Open Science Framework (DOI 10.17605/OSF.IO/CS7JX)). Established scoping review methods…
View details →Nieminen V, Martikainen MV, Kalliomäki S et al. · 2024 · International journal of radiation biology
Purpose Earlier evidence suggests that extremely low frequency magnetic fields (ELF MFs) can modify the effects of carcinogenic agents. However, the studies conducted so far with ionizing radiation as the co-exposure agent are sparse and…
View details →Gaviria M, Arave M, Phan N et al. · 2026 · Military medicine
Introduction Peripheral nerve injuries (PNIs) are associated with significant morbidity, and traditional repair techniques often result in incomplete functional recovery. Polyethylene glycol (PEG) fusion has been proposed as a technique to…
View details →Larson ME, Pan Y, Reidy L et al. · 2026 · PloS one
People with HIV (PWH) experience elevated cardiovascular disease risk compared to people without HIV. Stimulant use may further increase subclinical myocardial injury among PWH, but data on cardiovascular biomarkers, including serum…
View details →Geamănu A, Pîrvulescu RA, Tricorache D et al. · 2026 · Diagnostics (Basel, Switzerland)
Background: Hydroxychloroquine (HCQ) is widely used in systemic lupus erythematosus (SLE), yet cumulative exposure may result in progressive retinal toxicity. Structural biomarkers capable of identifying subclinical damage remain…
View details →Sung K · 2026 · Environmental management
Trail penetration within strictly designated protected areas is often treated as a conservation concern, yet its consequences for vegetation trends at national scales remain empirically unresolved. This study evaluated whether trail…
View details →Simonis L, Marcour Y, Embacher J et al. · 2026 · Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
Background & aims Assessment of hepatic steatosis is key for diagnosis and monitoring of steatotic liver disease. Controlled attenuation parameter is widely used, but concerns regarding its measurement variability exist. We evaluated the…
View details →Ünlü C, Aksoy H · 2026 · BMC pregnancy and childbirth
Background Anti-D immunoglobulin administered in the early third trimester to Rhesus D negative women with Rhesus D incompatibility is widely assumed to provide protection against silent fetomaternal haemorrhage until delivery. However,…
View details →Corn E, Becht K, Adefres B et al. · 2026 · Gynecologic oncology reports
Purpose Cervical cancer is the number one cause of cancer-related mortality for women in Botswana, where care is complicated by the country's severe shortage of gynecologic oncologists. Recent data suggests that "low-risk" stage I cervical…
View details →Martinos N, Kroupis C, Gypari M et al. · 2026 · Current issues in molecular biology
Background/objectives Histologic mucosal healing is an increasingly recognized therapeutic target in inflammatory bowel disease (IBD), yet reliable non-invasive correlates remain limited. This study aimed to evaluate circulating cytokine…
View details →Kim EJ, Kim SY, Kee YK et al. · 2026 · Preprint
Abstract Far-infrared (FIR) therapy has been proposed to improve vascular access flow (Qa) in patients receiving maintenance hemodialysis through an arteriovenous fistula (AVF) or arteriovenous graft (AVG). However, vascular access blood…
View details →Han P, Chen P, Zhang L et al. · 2026 · Preprint
Abstract Background Small-incision lenticule extraction (SMILE) removes an intrastromal lenticule whose stiffness differs between corneal meridians, producing measurable stromal mechanical anisotropy. Whether this meridional anisotropy…
View details →Walmsley SL, Nabipoor M, Qi F et al. · 2026 · Clinical & translational immunology
Objectives To assess neutralizing antibody responses to emerging SARS-CoV-2 variants. Methods We explored SARS-CoV-2 neutralizing antibodies in140 adults participating in a longitudinal study of antibody responses to COVID vaccines.…
View details →Bermingham MD, Meredith RT, Mills H et al. · 2026 · Frontiers in allergy
Quantifying food allergens in complex matrices is hindered by thermal processing, particularly in baked products used for oral food challenges (OFCs), where limited data exists on effects on clinically relevant allergens. To address this,…
View details →Kennedy J, Cooley SA, Roman Fox J et al. · 2026 · The Journal of infectious diseases
Background As persons with human immunodeficiency virus (PWH) live longer, interactions between human immunodeficiency virus (HIV), aging, and structural brain integrity become increasingly vital for understanding cognitive disorders. This…
View details →Watrobska CM, Codd J, Portugal SJ et al. · 2026 · The Journal of experimental biology
The brain is energetically expensive. Therefore, energy availability may determine whether costly cognitive processes such as long-term memory can be expressed. However, there is a limited understanding of the metabolic costs associated…
View details →Kuo MC, Younan SA, Williams PJ et al. · 2026 · Techniques in coloproctology
Background Robotic approach is increasingly being used for surgery in Crohn's disease. Robotic ileocolic resection (ICR) for Crohn's disease (CD) is comparable to laparoscopic ICR for short term outcomes; however, no studies have compared…
View details →Flora RJ, Bullo J, Talaban J et al. · 2026 · Preprint
Abstract Organochlorine pesticides (OCPs) are persistent organic pollutants known for their environmental stability, hydrophobicity, and strong potential for bioaccumulation. Although many OCPs have been banned or restricted under…
View details →Jankovič P, Chodzyński KJ, Vanrossomme AE et al. · 2026 · Neurology international
Background The risk stratification of unruptured intracranial aneurysms (UIAs) relies largely on static clinical and morphological parameters, which may not fully capture aneurysm-specific wall behavior. ECG-gated four-dimensional computed…
View details →Kanack AJ, Mauch EE, Kohlhagen MC et al. · 2026 · Preprint
ABSTRACT Background Monoclonal gammopathy of thrombotic significance (MGTS) is a recently described chronic prothrombotic condition characterized by monoclonal anti-PF4 antibodies that are detected above the polyclonal antibody background…
View details →Mirza S, Fine L, McClure JA et al. · 2026 · Antibiotics (Basel, Switzerland)
Background Staphylococcus aureus acquires methicillin resistance genes through the SCC mec element. Although spontaneous SCC mec excision has been observed, its frequency, type-specific variation, and responsiveness to environmental…
View details →Shahri ZJ, Noda A, Hayashi T et al. · 2026 · Preprint
Abstract Whether developmentally competent pancreatic progenitors can restore pancreatic structure and metabolic function in a defective host environment remains unclear. Here, we used intraplacental transplantation to compare the fate of…
View details →Buttke DE, Kaplan BS, Jones LC et al. · 2026 · Journal of wildlife diseases
Mycoplasma bovis is a growing threat to American bison (Bison bison) health and restoration efforts, causing significant mortality and disease in affected bison herds. Despite this, little is known about the epidemiology or clinical course…
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