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Browse the failure-mode index

21,770 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Biomagnetism of oral tissues and external magnetic field interactions with cell membranes, oral microflora, and orthodontic magnetic therapies: A review.

Itabaiana Sobrinho S, Meira-Belo LC, Mohallem NDS · 2026 · Progress in biophysics and molecular biology

Various rare earth magnets have been successfully applied in clinical orthodontics; however, their interactions with the oral environment remain only partially understood. Various controversies remain regarding magnetic fields (MFs) in…

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Negative / Null Result ReportMedicine

Effects of Glucagon-Like Peptide-1 Receptor Agonists (Mono and Combination Therapy) on Energy Expenditure: A Scoping Review.

Vieira FT, Deng Z, Muller MJ et al. · 2026 · Obesity reviews : an official journal of the International Association for the Study of Obesity

Introduction Weight loss results in reduced energy expenditure (EE) due to body composition alterations (e.g., fat-free mass and fat mass losses) and mass-independent adaptations in EE (e.g., hormones). Glucagon-like peptide-1 receptor…

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Negative / Null Result ReportMedicine

Intraoperative biopsy challenges: Cavernous sinus meningioma mimic.

Pérez Serena A, Martínez Betancourt DP · 2026 · Neurocirugia

We report the case of a 56-year-old female patient with controlled Human Immunodeficiency Virus (HIV) who presented with binocular diplopia and a known sixth cranial nerve palsy. Imaging revealed a lesion centered in the right cavernous…

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Negative / Null Result ReportMedicine

Lost in submission? Investigating publication bias in regional anaesthesia: A pilot case study of the erector spinae plane block.

De Cassai A, Dost B, Karapinar YE et al. · 2026 · Revista espanola de anestesiologia y reanimacion

Background The Erector Spinae Plane (ESP) block is a regional anaesthesia technique with a growing range of clinical applications due to its short learning curve, low complication rate, and effectiveness. However, publication bias can…

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Negative / Null Result ReportOpen accessMedicine

Glomerular Yield in Ultrasound-Guided Native Kidney Biopsies in Pediatric and Adult Populations With Age-Stratified Subgroups.

Ravizzini PC, Lino HA, de Faria Castro Fleury E et al. · 2025 · Cureus

Background This study compares the glomerular yield, mean number of biopsy cores, and complication rates between pediatric and adult populations undergoing ultrasound-guided native kidney biopsies. Additionally, the adult population was…

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Negative / Null Result ReportMedicine

Association between hemodynamically significant patent ductus arteriosus and fluid intake in the first week of life in a cohort of very low birth weight preterm infants: the COOL study.

Mayer A, Bresesti I, Francescato G et al. · 2025 · European journal of pediatrics

The amount of fluid to give in preterm infants with patent ductus arteriosus (PDA) is still highly debated, with no robust evidence that fluid restriction provides a clear benefit. The aim of the study is to evaluate if spontaneous closure…

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Negative / Null Result ReportMedicine

Assessing Blood Pressure, Mental Health, and HRV Responses to Integrated Acupuncture in Hypertensive Patients: A Pilot Randomized Controlled Trial.

Singh D, Kodali PB, Sharma G et al. · 2025 · Medical acupuncture

Abstract This study aimed to investigate the effects of an integrated acupuncture (IA) protocol on blood pressure (BP), depression, anxiety, stress scores, and heart rate variability (HRV) in hypertensive patients. Abstract The study was a…

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Negative / Null Result ReportMedicine

Serum 25-Hydroxyvitamin D Levels and Longitudinal Changes in Muscle Mass and Function in Peritoneal Dialysis Patients: A Prospective Cohort Study.

Wang L, Xue C, Zhu B et al. · 2026 · Journal of nutritional science and vitaminology

Data regarding to how serum 25 hydroxyvitamin D (25(OH)D) levels affect muscle mass and function in end-stage renal disease (ESRD) patients have led to inconclusive results. The main goal of this research was to examine the relationship…

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Negative / Null Result ReportOpen accessMedicine

Capsule Endoscopy-Guided Diagnosis of Small Bowel Lymphoma Presenting as Protein-Losing Enteropathy: Complementary Role of Peripheral Blood Flow Cytometry.

Abdulrasak M, Axler O, Kapás B et al. · 2026 · Diagnostics (Basel, Switzerland)

Protein-losing enteropathy (PLE) is an uncommon and often underrecognized manifestation of lymphoproliferative disorders and may be difficult to diagnose when conventional gastrointestinal investigations are unrevealing. We present an…

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Negative / Null Result ReportMedicine

The Role of Circulating Tumor DNA in Patients Treated with Adjuvant Immune Checkpoint Inhibitors: Clinical Reality or Distant Horizon?

Maffezzoli M, Nagpal R, Elewaily M et al. · 2025 · Current oncology reports

PURPOSE OF REVIEW: Adjuvant immunotherapy has improved outcomes in several cancers, although patient selection and toxicity remain challenges. Circulating tumor DNA (ctDNA) has emerged as a biomarker for minimal residual disease (MRD)…

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