Negative / Null Result Report
GONDA K, Ozaki A, Ito S et al. · 2026 · Preprint
Abstract In the setting of blood group chimerism/mosaicism, conventional BRCA1/2 genetic testing may yield inconclusive results. Multigene panel testing (MGPT) may overcome this limitation. We report a case in which BRCA2 pathogenic…
View details →Negative / Null Result ReportMedicine
Itabaiana Sobrinho S, Meira-Belo LC, Mohallem NDS · 2026 · Progress in biophysics and molecular biology
Various rare earth magnets have been successfully applied in clinical orthodontics; however, their interactions with the oral environment remain only partially understood. Various controversies remain regarding magnetic fields (MFs) in…
View details →Negative / Null Result ReportMedicine
Vieira FT, Deng Z, Muller MJ et al. · 2026 · Obesity reviews : an official journal of the International Association for the Study of Obesity
Introduction Weight loss results in reduced energy expenditure (EE) due to body composition alterations (e.g., fat-free mass and fat mass losses) and mass-independent adaptations in EE (e.g., hormones). Glucagon-like peptide-1 receptor…
View details →Negative / Null Result ReportMedicine
Pérez Serena A, Martínez Betancourt DP · 2026 · Neurocirugia
We report the case of a 56-year-old female patient with controlled Human Immunodeficiency Virus (HIV) who presented with binocular diplopia and a known sixth cranial nerve palsy. Imaging revealed a lesion centered in the right cavernous…
View details →Negative / Null Result ReportMedicine
De Cassai A, Dost B, Karapinar YE et al. · 2026 · Revista espanola de anestesiologia y reanimacion
Background The Erector Spinae Plane (ESP) block is a regional anaesthesia technique with a growing range of clinical applications due to its short learning curve, low complication rate, and effectiveness. However, publication bias can…
View details →Negative / Null Result ReportMedicine
Di Noia D, Maiorano MFP, Sanasi A et al. · 2026 · Journal of gynecology obstetrics and human reproduction
Radiation necrosis is a rare but serious complication of pelvic chemoradiotherapy that may closely mimic tumor recurrence on both imaging and clinical examination. We describe the case of a 43-year-old woman with FIGO stage II vaginal…
View details →Negative / Null Result ReportOpen accessMedicine
Ravizzini PC, Lino HA, de Faria Castro Fleury E et al. · 2025 · Cureus
Background This study compares the glomerular yield, mean number of biopsy cores, and complication rates between pediatric and adult populations undergoing ultrasound-guided native kidney biopsies. Additionally, the adult population was…
View details →Negative / Null Result ReportMedicine
Mayer A, Bresesti I, Francescato G et al. · 2025 · European journal of pediatrics
The amount of fluid to give in preterm infants with patent ductus arteriosus (PDA) is still highly debated, with no robust evidence that fluid restriction provides a clear benefit. The aim of the study is to evaluate if spontaneous closure…
View details →Negative / Null Result ReportMedicine
Singh D, Kodali PB, Sharma G et al. · 2025 · Medical acupuncture
Abstract This study aimed to investigate the effects of an integrated acupuncture (IA) protocol on blood pressure (BP), depression, anxiety, stress scores, and heart rate variability (HRV) in hypertensive patients. Abstract The study was a…
View details →Negative / Null Result ReportMedicine
Fazekas CL, Török B, Szabó A et al. · 2026 · Progress in neurobiology
Episodic memory and related forms of learning depend critically on the hippocampus, whose activity is regulated by brainstem inputs that remain incompletely understood. The midbrain median raphe region (MRR) is a key regulator of forebrain…
View details →Negative / Null Result ReportOpen accessMedicine
Li SH, Niu WW, Huo XX et al. · 2025 · World journal of gastroenterology
Background Gastric mucosa-associated lymphoid tissue (MALT) lymphoma presents with various clinical presentations and endoscopic features. While gastric lesions are primarily assessed via endoscopic forceps biopsy, pathological…
View details →Negative / Null Result ReportOpen accessMedicine
Soda M, Motoyama H, Adachi T et al. · 2026 · Surgical case reports
Introduction Gordonia species are rare aerobic Gram-positive actinomycetes and opportunistic pathogens. Their clinical manifestations and optimal management remain poorly defined. Gordonia sputi is an especially uncommon cause of…
View details →Negative / Null Result ReportMedicine
Senoo K · 2025 · Journal of cardiovascular electrophysiology
Atrial fibrillation (AF) is the most common sustained arrhythmia and raises ischemic stroke risk fivefold, even when asymptomatic. Early detection and timely initiation of oral anticoagulation can significantly reduce stroke incidence,…
View details →Negative / Null Result ReportOpen accessMedicine
Patel A, Esencan E, Lakhani Z et al. · 2026 · F&S reports
Objective To report an adult case of XX/XY chimera resulting from in vitro fertilization with transfer of three embryos, that was discovered with preconception genetic carrier screening. Design Case report. Subject A 33-year-old…
View details →Negative / Null Result ReportOpen accessMedicine
Phommasone K, Souksakhone C, Chanthongthip A et al. · 2025 · PloS one
Background Lao PDR reported a low number of confirmed SARS-CoV-2 cases until the introduction of COVID-19 vaccines in April 2021. This raised doubts about whether the reported number reflected the true situation and questioned about…
View details →Negative / Null Result ReportOpen accessMedicine
Carrillo Lizarazo JL, Cecchin D, Camozzi V et al. · 2025 · BJS open
Background Accurate preoperative localization is essential for successful, focused, minimally invasive surgery in primary hyperparathyroidism (PHPT). New imaging techniques have recently been proposed. This study evaluated the impact of…
View details →Negative / Null Result Report
D’Amario A, Ambrosini R, Gullino A et al. · 2025 · Preprint
Background: Ovarian cancer is a leading gynecological malignancy with high global mortality. Early and accurate diagnosis is essential for effective management, yet many ovarian masses remain indeterminate after initial assessment.…
View details →Negative / Null Result ReportMedicine
Wang L, Xue C, Zhu B et al. · 2026 · Journal of nutritional science and vitaminology
Data regarding to how serum 25 hydroxyvitamin D (25(OH)D) levels affect muscle mass and function in end-stage renal disease (ESRD) patients have led to inconclusive results. The main goal of this research was to examine the relationship…
View details →Negative / Null Result Report
Kiala Z, Petra S, Andarcia MG · 2026 · Preprint
Abstract Irrigated agriculture accounts for nearly 70% of global freshwater withdrawals, yet monitoring consumptive water use at field scale remains challenging in fragmented smallholder systems. FAO’s WaPOR database provides global…
View details →Negative / Null Result Report
Song P, Su J, Vraa CLK et al. · 2025 · Preprint
Lipid nanoparticles (LNPs) have proven to be an effective delivery system for RNA therapeutics. The chemical composition of LNPs determines their functional delivery efficiency and targeting properties, which vary between in vitro and in…
View details →Negative / Null Result ReportMedicine
Shiba Y, Aoki K, Ohka F et al. · 2025 · AJNR. American journal of neuroradiology
Background and purpose Differentiating between a brain tumor and a nontumorous lesion remains a diagnostic challenge, particularly when conventional imaging modalities such as CT and MRI provide inconclusive results. While 11 C-methionine…
View details →Short NoteMedicine
Ramos T, Georges C, Schiltz C · 2026 · Journal of experimental child psychology
Numbers and space are associated in the human brain. One of the most-studied spatial-numerical associations (SNAs) is the SNARC effect (Spatial Numerical Association of Response Codes), for which robust group-level effects are reported…
View details →Replication FailureMedicine
Rymaszewska J, Szcześniak D, Maciaszek J et al. · 2026 · Journal of affective disorders
The exploration of Theta Burst Stimulation (TBS) in Obsessive-compulsive disorder (OCD) treatment is still in its nascent stages, and these initial findings underscore the need for further research to optimize stimulation parameters and…
View details →Negative / Null Result ReportOpen accessMedicine
Kumar R, Gravett S, Jelic V et al. · 2026 · Neurology
Background and objectives The α-synuclein (α-syn) seed amplification assay (SAA) has shown promising results for diagnosing dementia with Lewy bodies (DLB) using CSF samples. A barrier to implementing α-syn SAA clinically is the use of…
View details →Negative / Null Result ReportMedicine
Tornvall S, Blomberg L, Hirschberg AL · 2025 · Psychoneuroendocrinology
The objective of this study was to investigate the association of menstrual cycle phases on sexual function, well-being, and mood in young healthy women. Previous research has shown inconclusive results likely due to using non-validated…
View details →Negative / Null Result ReportMedicine
Wilcox A, Hall M, Menzies J et al. · 2025 · Science of the Total Environment
The biodegradability of water-soluble carboxymethyl cellulose (CMC) polymer, degree of substitution of 0.65, was evaluated in screening and simulation assays using activated sludge as the inoculum. In an OECD 301B, CMC 0.65 was slowly…
View details →Negative / Null Result ReportOpen accessMedicine
Abdulrasak M, Axler O, Kapás B et al. · 2026 · Diagnostics (Basel, Switzerland)
Protein-losing enteropathy (PLE) is an uncommon and often underrecognized manifestation of lymphoproliferative disorders and may be difficult to diagnose when conventional gastrointestinal investigations are unrevealing. We present an…
View details →Negative / Null Result Report
Brataatmaja RH, Notari CF, Kam A et al. · 2025 · Preprint
Abstract Objectives: This umbrella review aimed to synthesize and critically evaluate the available evidence regarding the association between exposure to per- and polyfluoroalkyl substances (PFAS) and childhood obesity. Methods: A…
View details →Failed Experiment Report
Jiang H, Chase J, Fu L et al. · 2025 · Preprint
This study presents a case analysis of using AI systems as co-pilots in biological research, focusing on functional protein networks in invasive colorectal cancer. We used public proteomic data alongside ChatGPT, GitHub Copilot, and…
View details →Negative / Null Result ReportMedicine
Maffezzoli M, Nagpal R, Elewaily M et al. · 2025 · Current oncology reports
PURPOSE OF REVIEW: Adjuvant immunotherapy has improved outcomes in several cancers, although patient selection and toxicity remain challenges. Circulating tumor DNA (ctDNA) has emerged as a biomarker for minimal residual disease (MRD)…
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