Negative / Null Result ReportOpen accessMedicine
Vallesi V, Galléa C, Sritharan J et al. · 2025 · Brain communications
Functional paralysis (FP), a subtype of functional neurological disorder (FND), is characterized by symptoms of paralysis without clinically evident damage to the nervous system. Previous research has reported impaired inhibitory control…
View details →Negative / Null Result ReportMedicine
Erickson MG, Zanton GI, Wattiaux MA · 2023 · Journal of dairy science
Limited research has examined the interaction between dietary crude protein (CP) level and CP feeding pattern. We tested CP level (low protein [LP], 13.8%; high protein [HP], 15.5% CP, dry matter [DM] basis) and CP feeding pattern (OF =…
View details →Negative / Null Result ReportMedicine
Speed LJ, de Valk J, Croijmans I et al. · 2023 · Cognitive science
Odor and color are strongly associated. Numerous studies demonstrate consistent odor-color associations, as well as effects of color on odor perception and language. Yet, we know little about how these associations arise. Here, we test…
View details →Negative / Null Result ReportOpen accessMedicine
Goldway N, Markovits T, Fine N et al. · 2026 · Biological psychiatry global open science
Background Dissociation, an altered state of consciousness in which individuals feel detached from their body, environment, and sense of self, is a common feature of posttraumatic stress disorder (PTSD). Despite its significance, the…
View details →Failed Experiment ReportMedicine
Højsgaard Chow H, Talbot J, Lundell H et al. · 2023 · Multiple sclerosis and related disorders
Introduction Dimethyl fumarate treatment is approved in Europe for patients with relapsing-remitting multiple sclerosis (MS) and in the US for relapsing forms of MS. We recently published the results of the first randomized…
View details →Failed Experiment ReportOpen accessMedicine
Goel S, Jovanović B, Chu X et al. · 2025 · Clinical cancer research : an official journal of the American Association for Cancer Research
Purpose Cyclin-dependent kinase 4/6 inhibitors can significantly extend survival when given in combination with endocrine therapy in patients with hormone receptor-positive metastatic breast cancer. However, their activity has been…
View details →Failed Experiment ReportMedicine
Buchtele N, Schörgenhofer C, Schwameis M et al. · 2022 · American journal of respiratory and critical care medicine
Rationale: Prostaglandin E 1 (alprostadil; PGE 1 ), in addition to low-dose unfractionated heparin, increases the biocompatibility of extracorporeal systems and enhances the efficacy of artificial organs without increasing bleeding risk.…
View details →Methods Dead-EndOpen accessMedicine
Zhu J, Li Z, Song D et al. · 2026 · BMC health services research
Background The IMforte trial had supported lurbinectedin as a recommended first-line maintenance therapy for patients with extensive-stage small-cell lung cancer (ES-SCLC), while its cost-effectiveness remains uncertain for patients and…
View details →Failed Experiment ReportOpen accessMedicine
Fabbroni C, Grignani G, Vincenzi B et al. · 2024 · ESMO open
Background This is a multicentre, single-arm, phase II study aimed at further exploring the activity of trabectedin as second-/further-line treatment in retroperitoneal leiomyosarcoma (LMS) and well-differentiated/dedifferentiated…
View details →Negative / Null Result ReportOpen accessMedicine
Marek MJ, Wolke D, Sorg C et al. · 2026 · NeuroImage. Clinical
This study investigates the long-term effects of very preterm (VPT) birth (<32 weeks of gestation) on cognitive control and structural brain network topology. Data were obtained from 61 very VPT and 79 full term (FT) individuals aged 26…
View details →Negative / Null Result Report
Grave J, Cordeiro S, De Sá Teixeira NA et al. · 2022 · Preprint
Schizotypy, a personality structure that resembles schizophrenia symptoms, is often associated with abnormal facial emotion perception. Based on the prevailing sense of threat in psychotic experiences, and the immediate perceptual history…
View details →Negative / Null Result Report
Guerreiro M, Borges F, Santos C et al. · 2023 · Preprint
Abstract Climate change is expected to produce major effects across marine life, and cephalopods seem to benefit from these effects. Of these animals, squids exhibit the greatest levels of biomass and of a substantial importance for human…
View details →Negative / Null Result ReportOpen accessMedicine
Park I, Campbell N, Nolte T et al. · 2026 · Acta neuropsychiatrica
Objective Borderline personality disorder (BPD) is characterised by instability in interpersonal relationships, self-image, and affect. Dysregulated negative emotional processing involving prefrontal and limbic circuits is considered a…
View details →Negative / Null Result Report
Cuttler C, Petrucci AS, LaFrance EM · 2022 · Preprint
Abstract Extremely high-potency cannabis concentrates are becoming increasingly available and popular among consumers. While prior research indicates these products are perceived to have greater detrimental effects relative to cannabis…
View details →Negative / Null Result ReportOpen accessMedicine
Doll-Lee J, Passarotto E, Altenmüller E et al. · 2025 · Journal of movement disorders
Objective This study investigated the impact of extrainstrumental workload on musician's dystonia (MD) and its relationship with playing ability by testing whether dystonia onset is more severe in the dominant hand and whether improvement…
View details →Negative / Null Result Report
Tsuji N, Imaizumi S · 2022 · Preprint
Sense of agency (SoA) is a feeling of controlling one’s own action. Recognition memory can improve for stimuli that involve SoA perhaps because of the self-reference effect. Recognition memory consists of recollection (i.e., detailed…
View details →Negative / Null Result ReportOpen access
Kist A, Pereira M, Msheik R et al. · 2024 · Preprint
Most human studies on perceptual decision-making are correlational, and few addressed the causal role of the neural markers they identify. Here, we took the opportunity offered by deep brain stimulation to study the causal role of…
View details →Negative / Null Result ReportOpen accessMedicine
Springer-Sapp CB, Ogbara OO, Addison O et al. · 2025 · The Journal of frailty & aging
Background The progression of sarcopenia with aging may be related to mitochondrial dysfunction due in part to altered mitochondrial dynamics (fusion, fission, mitophagy, and biogenesis). Previous work has identified altered expression of…
View details →Negative / Null Result ReportMedicine
Connor JJ, Johnson-Agbakwu C, Harlow BL et al. · 2026 · Journal of sex research
Female genital cutting (FGC) results in a higher risk for sexual issues in impacted women. This study examined this impact in a sample of 300 women identifying as Somali and living in the United States. FGC is highly prevalent in Somalia,…
View details →Failed Experiment ReportOpen accessMedicine
Miranda MC, Hyde J, Salazar K et al. · 2024 · microPublication biology
Prenatal stress is hypothesized to contribute to the development of schizophrenia. Lee and colleagues determined that prenatal stress in rats decreases levels of Dpysl2, which is found to be inactivated in schizophrenic patients. UNC-33 ,…
View details →Negative / Null Result ReportOpen accessMedicine
Fusagawa H, Sato T, Naito A et al. · 2025 · Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Overuse-induced muscle disorders (OIMD) frequently occur in athletes due to excessive and improper use under high physical demand, often leading to muscle pain and weakness. Limited studies have shown intramuscular fibrosis in OIMD, with…
View details →Negative / Null Result ReportMedicine
Foster BA, Zhou C, Canty E et al. · 2023 · Hospital pediatrics
Background Tolerance of uncertainty may influence how physicians and other providers practice and make clinical decisions. We hypothesized that increased tolerance of uncertainty would be associated with an increased uptake of a quality…
View details →Negative / Null Result Report
Steffen J, Fischbach PC, Gönner L et al. · 2022 · Preprint
ABSTRACT Background Etiological theories of addictive behavior postulate a key role for decision-making mechanisms. However, current research is lacking clear computational models for decision-making in multi-step forward planning…
View details →Negative / Null Result ReportMedicine
Yee CS, Demirdji M, Bailey KN et al. · 2026 · Osteoarthritis and cartilage
Objective Cartilage in the knee and temporomandibular joint (TMJ) rely on subchondral bone for joint homeostasis, whereby osteoarthritis (OA) causes degeneration. In the knee, suppression of osteocytic perilacunocanalicular remodeling…
View details →Negative / Null Result ReportOpen accessMedicine
Byg LM, Wang CA, Attia J et al. · 2026 · Communications medicine
Background Early life nutrition is associated with child behaviour; however, the interplay with genetic vulnerability is understudied. We hypothesised that psychiatric genetic risk interacted with early nutrition to predict behavioural…
View details →Negative / Null Result ReportOpen accessMedicine
Najberg H, Tapparel M, Holmann JN et al. · 2026 · Imaging neuroscience (Cambridge, Mass.)
Response training, such as with the Go/NoGo task, reduces the value of trained items by requiring participants to repeatedly inhibit their responses to appetitive cues that typically elicit approach tendencies. This devaluation is thought…
View details →Negative / Null Result ReportMedicine
van Timmeren T, Piray P, Goudriaan AE et al. · 2023 · Addictive behaviors
The development of addictive behaviors has been suggested to be related to a transition from goal-directed to habitual decision making. Stress is a factor known to prompt habitual behavior and to increase the risk for addiction and…
View details →Negative / Null Result ReportOpen accessMedicine
Eldesouky L, Gross JJ, English T · 2025 · Scientific reports
The ways people manage their emotions (emotion regulation; ER) have been found to affect their own well-being and the well-being of others. In the present research, we extended prior work by examining whether similarity between people's ER…
View details →Negative / Null Result ReportOpen accessMedicine
Hernandez C, Jensen CD, Duraccio KM · 2025 · Sleep advances : a journal of the Sleep Research Society
Study objectives This secondary data analysis study was designed to evaluate demographic and socioeconomic characteristics that may increase the magnitude of the impact of experimentally induced shortened sleep on suboptimal eating…
View details →Negative / Null Result ReportMedicine
McDonald MJ, Marsh ML, Fears SD et al. · 2025 · Journal of applied physiology (Bethesda, Md. : 1985)
Chronic exposure to shortened sleep is associated with an increased risk of Alzheimer's disease and dementia. Previous studies show insufficient (e.g., poor or fragmented) sleep impairs cerebrovascular reactivity to metabolic stress and…
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