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WASTE Journal

Browse the failure-mode index

21,770 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Effects of tumour necrosis factor and interleukin-6 inhibitor therapy on exercise-related visceral adipose tissue reduction in rheumatoid arthritis.

Jønck S, Adamsen ML, Rasmussen IE et al. · 2026 · Experimental physiology

Excess visceral adipose tissue (VAT) mass increases cardiovascular disease risk. Exercise supports overall health and VAT mass reduction in rheumatoid arthritis (RA). Unlike tumour necrosis factor (TNF), interleukin-6 (IL-6) is upregulated…

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Negative / Null Result ReportMedicine

Primary Prophylaxis for Clostridioides difficile Infection in Lung Transplant Recipients: A Retrospective Study.

Irwin M, Leedy N, Nandavaram S et al. · 2026 · Transplant infectious disease : an official journal of the Transplantation Society

Background Clostridioides difficile infection (CDI) is a common complication in patients receiving broad-spectrum antibiotics and causes significant morbidity, especially in solid organ transplant recipients. Oral vancomycin has shown…

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Negative / Null Result ReportMedicine

Comparison of international league of associations for rheumatology and pediatric rheumatology international trials organization classification criteria for juvenile idiopathic arthritis: insights from an African multicenter cohort.

Hamdi W, Ben Nessib D, Hashad S et al. · 2025 · European journal of pediatrics

The International League of Associations for Rheumatology (ILAR) classification criteria for juvenile idiopathic arthritis (JIA) are currently widely used in clinical practice. However, new criteria have recently been proposed by the…

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Negative / Null Result ReportMedicine

Biodegradable patch based on chitosan-collagen with glycerol plasticizer as scaffold for tympanic membrane perforation.

Widiyanti P, Putra AF, Rudyardjo DI · 2026 · The International journal of artificial organs

Perforation on tympanic membrane could decrease the hearing ability. In some cases, myringoplasty should be performed. Myringoplasty requires material as patch to cover tympanic membrane's hole. This study is aimed to create innovation…

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Negative / Null Result ReportMedicine

Effect of neuromuscular blockade on opioid consumption in high-risk children undergoing adenotonsillectomy: A randomized-controlled trial.

Efune PN, Nakonezny PA, Pinales P et al. · 2026 · Journal of clinical anesthesia

Background Protective reflexes like coughing occur frequently during pediatric adenotonsillectomy (AT) and are difficult to blunt with anesthetics, potentially leading to higher than necessary opioid administration. Our objective was to…

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Negative / Null Result ReportMedicine

Impact of Violet LED Light and High-Concentration Hydrogen Peroxide on Dentin Mechanical Properties, Collagen, and Enzymatic Activity.

Damázio AH, Carlos NR, Basting RT et al. · 2026 · Operative dentistry

Objective Because the application of violet light-emitting diode (LED) light may enhance the release of reactive oxygen species, and its combination with a high-concentration bleaching agents may accelerate collagen degradation, this study…

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Negative / Null Result ReportMedicine

Impact of Vancomycin-Resistant Enterococci (VRE)-Active Perioperative Prophylaxis in Liver Transplant Patients Colonized by VRE.

Burastero GJ, Wey EQ, Guidetti V et al. · 2026 · Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Background Data regarding the effectiveness of vancomycin-resistant Enterococci (VRE)-active prophylaxis for preventing early post-liver transplantation (LT) VRE infections in VRE-colonized patients are scarce. Methods 131 pre-LT…

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Negative / Null Result ReportMedicine

Prostate cancer mortality among men with and without comorbidity: Long-term results from the European randomized study of screening for prostate cancer Rotterdam.

Westerhout SF, Remmers S, Bangma CH et al. · 2026 · European journal of cancer (Oxford, England : 1990)

Introduction Prostate-specific antigen (PSA)-based prostate cancer (PCa) screening can be improved by individualised, risk-stratified strategies. Comorbidity influences life expectancy, so may affect benefits of screening. We evaluated…

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Negative / Null Result ReportMedicine

Telehealth education for patients with cancer: a standalone solution for symptom relief?

Ruegg T, Zhao X, Mount MS et al. · 2026 · Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Background Telehealth-delivered education offers a practical approach to chemotherapy teaching and symptom self-management support. Advanced practice providers (APPs) play an increasingly vital role in guiding oncology patients through…

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Negative / Null Result ReportMedicine

The impact of closed-incision negative-pressure therapy on donor-site outcomes in drainless abdominal free flap breast reconstruction.

Kim J, Park C, Woo KJ et al. · 2026 · Journal of plastic, reconstructive & aesthetic surgery : JPRAS

Concerns regarding donor-site healing persist in abdominal-based free flap breast reconstruction. Although closed-incision negative-pressure therapy (CINPT) has demonstrated wound-related benefits, its efficacy without the use of drains…

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Negative / Null Result ReportMedicine

The impact of tracheal intubation attempts on chest compression fraction during pediatric CPR: a report from the Videography in Pediatric Resuscitation (VIPER) collaborative.

Jariyasakoolroj T, O'Connell K, MacDonald T et al. · 2026 · Resuscitation

Aim To examine the association between tracheal intubation (TI) attempts and chest compression (CC) pauses on chest compression fraction (CCF) during pediatric CPR across a network of emergency departments. Methods Prospective…

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Negative / Null Result ReportMedicine

Deciphering serotonin's functional role in postharvest: Fruit-specific preservation of red fruit quality.

Arabia A, Muñoz P, Álvarez-Real S et al. · 2026 · Plant science : an international journal of experimental plant biology

Serotonin is a widely conserved signaling molecule essential for plant development and stress responses, but its role in fruit postharvest physiology remains largely unexplored. This study aimed to evaluate the effects of 100 μM exogenous…

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Negative / Null Result ReportMedicine

Lactated Ringer's Solution at a Standard Infusion Rate in Post-endoscopic Retrograde Cholangiopancreatography Pancreatitis Prevention: A Retrospective Comparative Study.

Ko T, Sakai A, Nakano R et al. · 2026 · Digestive diseases and sciences

Background Post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis is a common complication, and its prevention remains challenging. Although aggressive infusion of lactated Ringer's solution (hereafter Lactated Ringer's)…

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Negative / Null Result Report

Using Narrative to Explain Uncertainty in Climate Change

Freeman G, Rousseau A, Brunton M et al. · 2025 · Preprint

Abstract This study presents the findings on the use of narrative when communicating complex scientific uncertainties. A growing body of evidence in narrative cognition and communication has shown promise for the use of narrative in…

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Negative / Null Result ReportMedicine

Longitudinal Reliability of Rheumatology Patient Safety Measures and Implications for CMS Case Minimums.

Roberts ET, Schmajuk G, Fitzpatrick J et al. · 2026 · Joint Commission journal on quality and patient safety

Background Metrics with acceptable reliability are necessary to ensure that quality measures reward performance. Low metric reliability may result from a lack of differences between reporting entities or low numbers of eligible patients.…

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Negative / Null Result ReportOpen accessMedicine

Long-term changes in overjet in individuals with and without orthodontic treatment : A 30-year cohort study.

Bokan J, Schmid JQ, Middelberg C et al. · 2026 · Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie

Purpose Large overjet increases the risk of traumatic dental injury (TDI). This study, part of the Münster Long-Term Study (MLS), aimed to investigate long-term changes in overjet with or without orthodontic treatment and to evaluate…

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Negative / Null Result ReportMedicine

Incidence, Predictors, and Outcomes of Stroke Following Transcatheter Aortic Valve Implantation: A Multicenter Australian Experience.

Butala AD, Nanayakkara S, Johnston R et al. · 2026 · The American journal of cardiology

Stroke is a serious complication following transcatheter aortic valve implantation, associated with increased disability and mortality. Despite this, there is a lack of patient-level data examining stroke in contemporary, lower-risk…

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Negative / Null Result ReportMedicine

Letter to the Editor: Comment on Adamovich-Zeitlina et al's "Clinical Outcomes of Boston Type 1 Keratoprosthesis With and Without Endophthalmitis During the Covid-19 Pandemic".

Geoffrion D, Mikhail D, Rizk M et al. · 2025 · Ocular immunology and inflammation

Authors reported an 18% rate of endophthalmitis in Boston type 1 keratoprosthesis (KPro) patients, higher than previously reported rates. Most cases occurred during the COVID-19 pandemic, likely due to reduced access to care. Bandage…

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