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Browse the failure-mode index

21,770 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

The effect of video assisted instruction on central venous catheter application skills, anxiety and satisfaction in nursing students: a randomised controlled study.

Koç G, Yüce Başaran HD, Yavuz B et al. · 2026 · BMC medical education

Objective This study aimed to evaluate the effect of video-assisted instruction on central venous catheter (CVC)-related psychomotor skills (blood collection, drug administration, and dressing care), anxiety levels, and student…

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Negative / Null Result ReportOpen accessMedicine

Antibacterial and anti-biofilm effects of postbiotic mediator derived from <i>Jeotgal</i> isolate <i>Lactiplantibacillus plantarum</i> KMC12 against <i>Streptococcus mutans</i>.

Oh H, Kim J, Bai J · 2026 · Journal of oral microbiology

Background Dental caries, commonly known as tooth decay, is a progressive breakdown of tooth tissues caused by the biofilm-producing bacteria, Streptococcus mutans . S. mutans plays a primary role in the initiation and progression of…

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Negative / Null Result ReportOpen accessMedicine

Empagliflozin enhances cisplatin activity in chemo-resistant EJ138 bladder cancer cells: The importance of anti-diabetic medications in cancer treatment.

Shariati S, Mohtadi S, Molavinia S et al. · 2026 · Scientific reports

Anti-diabetic medications have been found to reduce chemotherapy resistance. This study sought to investigate the role of Empagliflozin (Empa) as an anti-diabetic medication in reversing Cisplatin (Cis) resistance in EJ138 bladder cancer…

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Negative / Null Result ReportOpen accessMedicine

Selected immunoendocrine and performance adaptations to upper-body plyometric training and β-alanine supplementation in male swimmers.

Gao H, Yu X, Guo Z · 2026 · Journal of the International Society of Sports Nutrition

Background Upper-body plyometric training (PT) enhances neuromuscular performance and power production. However, its application in swimming and its potential interaction with β-alanine (BA) supplementation remain largely unexplored.…

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Negative / Null Result ReportMedicine

Evaluation of Point-of-Care Coagulation Measurement Systems for Activated Clotting Time and Partial Thromboplastin Time in Heparinized and Non-Heparinized Equine Blood.

Hobbs KJ, Ueda Y, Qu Y et al. · 2026 · Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)

Objectives To compare the performance of one point-of-care activated clotting time (ACT) machine (Vet-Tube), one point-of-care activated partial thromboplastin time (aPTT) machine (Coagulation DX), and one bench-top ACT machine (Medtronic…

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Negative / Null Result ReportMedicine

Homemade Ultrasound Stand-Off Gel Pads: A Multi-Parameter Performance Study.

William MFGBMF, Jamil NAB, Leong SS et al. · 2026 · Australasian journal of ultrasound in medicine

Aim Stand-off gel pads made of natural ingredients may provide a low-cost option in clinical ultrasound imaging. This study investigated the performance and safety of homemade pads. Methods Thirty stand-off gel pads were made of aloe vera,…

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Negative / Null Result ReportOpen accessMedicine

Evaluation of soluble transferrin receptor and malondialdehyde levels associated with ferroptosis in children with familial Mediterranean fever in remission.

Dogantan S, Keskin A, Yücel BB et al. · 2026 · Revista da Associacao Medica Brasileira (1992)

Objective Familial Mediterranean fever, an autoinflammatory disease, is characterized by recurrent stereotypic febrile attacks associated with an inflammatory syndrome. Malondialdehyde, a lipid peroxidation marker, and soluble transferrin…

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Negative / Null Result ReportMedicine

Sirolimus-based treatment regimens for antinuclear antibody (ANA)-positive immune thrombocytopenia: a retrospective single-center cohort study.

Tan A, Liu J, Chen X et al. · 2026 · Hematology (Amsterdam, Netherlands)

Objectives To evaluate the efficacy and safety of sirolimus-based treatment regimens in patients with antinuclear antibody (ANA)-positive immune thrombocytopenia (ITP). Methods This retrospective single-center study enrolled patients with…

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Negative / Null Result ReportOpen accessMedicine

Melody vs. message: Effects of traditional song and concise social media communications on iodine knowledge, attitudes, behaviors, and biomarkers in pregnant women-A randomized controlled trial.

Ruengsiriphakakul S, Bumrerraj S, Thaenkham T · 2026 · Journal of education and health promotion

Background Iodine deficiency remains a global public health problem. Urinary iodine concentration (UIC) in pregnant women is a key indicator of iodine status in the population. Knowledge (K), attitude (A), and practice (P) levels of…

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Negative / Null Result ReportOpen accessMedicine

Novel Taiwan-I-type infectious bronchitis virus: First evidence of testicular atrophy and efficacious protection with strain-matched oil-emulsified inactivated vaccine.

Zhang T, Xie Y, Yang C et al. · 2026 · Virulence

The Taiwan-I-type infectious bronchitis virus (IBV) has become one of the most dominant and threatening genotypes circulating in China poultry farms. In this study, we characterized the Taiwan-I-type IBV strain GX-NN200723 and evaluated…

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Negative / Null Result ReportOpen accessMedicine

A comparative evaluation of apical sealing ability of NeoPutty, Biodentine, and Bio-c repair using a radioactive isotope method - An <i>in vitro</i> study.

Rathore S, Bhushan J, Uppal AS et al. · 2026 · Journal of conservative dentistry and endodontics

Background Treatment of teeth with immature apices is difficult to manage by conventional endodontics. Apical barrier formation using bioceramic materials offers a biologically favorable solution, providing a hermetic seal that supports…

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Negative / Null Result ReportMedicine

The Effect of Virtual Simulation of Parenteral Medication Administration on Nursing Students' Knowledge and Skills: A Randomized Controlled Experimental Study.

Biyik Bayram S, Gülnar E, Çalişkan N et al. · 2026 · Computers, informatics, nursing : CIN

This study investigated the effect of virtual simulation of parenteral medication administrations on nursing students' knowledge and skills. This randomized controlled experimental study adopted a pretest-posttest research design. The…

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Negative / Null Result ReportOpen accessMedicine

Evaluation of Time-Dependent Chemical Alterations in Sodium Hypochlorite Solution Kept on the Unit Tray During an Average Root Canal Treatment Period.

Bastug Guven E, Genc Sen O · 2026 · Medical science monitor : international medical journal of experimental and clinical research

BACKGROUND Sodium hypochlorite (NaOCl) is the most commonly used irrigant in root canal treatment because of its antimicrobial activity and tissue-dissolving capacity. Since these properties are related to its physicochemical…

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Negative / Null Result ReportOpen accessMedicine

Evaluation of the Advantages of Silicone Stent in Revision Endoscopic Dacryocystorhinostomy in a Tertiary Care Hospital.

Sonawane C, Raval RR, Bajaj A et al. · 2026 · International archives of otorhinolaryngology

Introduction Silicone stents are often employed in dacryocystorhinostomy (DCR) procedures to maintain the patency of the newly created tear drainage passage during the healing stage. These stents are flexible, biocompatible, and generally…

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Negative / Null Result ReportOpen accessMedicine

The effect of timing on rehabilitation results in tumor-related spinal cord injuries.

Yorulmaz E, Geler-Kulcu D, Ramazanoglu AF et al. · 2026 · Turkish journal of physical medicine and rehabilitation

Objectives This study aims to investigate the impact of early initiated rehabilitation on outcomes in patients with spinal cord injuries related to tumors. Patients and methods In this retrospective cohort study conducted between January…

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Negative / Null Result ReportOpen accessMedicine

Acute Effect of Percussive Massage on Cross-Section Area, Muscle Strength, and Late Muscle Pain of the Quadriceps Muscle Following a Fatigue Protocol in Physically Active Men: Randomized Clinical Trial.

da Rosa Castilho A, Aguiar AF, Ribeiro AS et al. · 2026 · Physiotherapy research international : the journal for researchers and clinicians in physical therapy

Background and purpose The massage gun is widely used to alleviate delayed-onset muscle soreness (DOMS); however, empirical evidence regarding its physiological effects remains limited. Objectives This study aimed to evaluate the acute…

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Negative / Null Result ReportMedicine

Less Is More! An Analysis of Postoperative Outcomes Comparing Low-Dose E. Coli-Derived rhBMP-2 and Mammalian rhBMP-2 in Lateral Lumbar Spinal Fusion Surgery.

Chiu ST, Seah SJ, Zeng GJ et al. · 2026 · Clinical spine surgery

Study design Retrospective clinical study. Objective Investigating the fusion effect and side effect profile between low-dose E.BMP-2 and mammalian rhBMP-2. Summary of background data Recombinant human bone morphogenetic protein-2…

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Negative / Null Result ReportOpen accessMedicine

Clinical outcomes of implants in atrophic ridges augmented with collagenated xenogeneic or autogenous bone: 4-year follow-up of a randomized clinical trial.

Romito GA, Soares HH, Nishyama R et al. · 2026 · Brazilian oral research

This study aimed to evaluate the long-term outcomes of dental implants placed in alveolar ridges augmented with collagenated xenogeneic bone blocks (CXBB) or autogenous bone blocks (ABB). In this non-interventional study, 20 patients…

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