Negative / Null Result ReportOpen accessMedicine
Mao J, Gan Y, Tan X et al. · 2025 · International journal of women's health
Objective High basophil count levels are associated with an increased risk of gestational diabetes mellitus (GDM). We used two-sample Mendelian randomisation (MR) to explore a potential causal relationship. It also aims to offer genetic…
View details →Negative / Null Result ReportOpen accessMedicine
Killer HE, Pircher A, Stekhoven DJ · 2026 · Ophthalmology and therapy
Introduction The Collaborative Normal-Tension Glaucoma Study (CNTGS) is frequently cited as evidence that a 30% reduction in intraocular pressure (IOP) slows progression in normal-tension glaucoma (NTG). This study re-examines the…
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Schulz KM, Chavez MC, Forrester-Fronstin Z · 2024 · Preprint
Early pubertal onset during adolescence is consistently linked with increased risk of anxiety and depression in girls. Although estradiol tends to have anxiolytic effects in adulthood, whether sensitivity to estradiol’s anxiolytic actions…
View details →Negative / Null Result ReportMedicine
Yang Z, Su Q, Gao J et al. · 2026 · Acta psychologica
Scholars have emphasized the need for longitudinal research to investigate the reciprocal influence of personal belief in a just world (PBJW) and aggressiveness, yet such investigations remain limited. The current study aimed to examine…
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Poisson CL, Green IK, Stemmler GM et al. · 2024 · Preprint
To navigate dynamic environments, animals must rapidly integrate sensory information and respond appropriately to gather rewards and avoid threats. It is well established that dopamine (DA) neurons in the ventral tegmental area (VTA) and…
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Matsushima T, Toji N, Wada K et al. · 2024 · Preprint
Embryonic exposure to valproic acid (VPA) and imidacloprid (IMI, a neonicotinoid insecticide) impairs filial imprinting in hatchlings, and the deteriorating effects of VPA are mitigated by post-hatch injection of bumetanide, a blocker of…
View details →Negative / Null Result ReportOpen accessMedicine
Zheng H, Chen W · 2026 · Frontiers in pediatrics
Background and aims Exclusive enteral nutrition is an established induction therapy for pediatric Crohn's disease, but biochemical response varies across patients. We assessed whether baseline gut microbiome features were associated with…
View details →Negative / Null Result ReportMedicine
Che Y, Yuan J, Guo J · 2025 · Archives of dermatological research
Observational studies have shown that the risk of developing herpes zoster (HZ) increases with the use of statins. However, there are many confounding factors in observational studies. Therefore, our Mendelian randomization (MR) study…
View details →Negative / Null Result ReportOpen accessMedicine
Tu Y, Xie D, Qian H · 2025 · Medicine
Observational studies have suggested associations between circulating creatine kinase (CK) levels and gastric cancer (GC), yet causality remains uncertain. To evaluate whether genetically predicted CK levels are causally related to GC…
View details →Negative / Null Result ReportMedicine
van Lennep JPA, van Middendorp H, Leong OV et al. · 2025 · Scandinavian journal of pain
Objectives To understand how different individuals respond to placebo effects, it is relevant to disentangle the influence of someone's personality and genetic variations. The aim of this exploratory study was to investigate the role of…
View details →Negative / Null Result ReportMedicine
Salehi-Reyhani SM, Saadat M · 2024 · Molecular biology reports
Background It is well known that telomerase activity is suppressed in normal human tissues and reactivated in tumors, suggesting that the human telomerase reverse transcriptase (hTERT, MIM: 187270) gene may be involved in carcinogenesis. A…
View details →Negative / Null Result ReportMedicine
Naito R, Hiwa R, Inaba R et al. · 2025 · Modern rheumatology case reports
Vesiculobullous dermatomyositis (VD) is a rare manifestation of dermatomyositis (DM) and has been suggested to be associated with malignancy. Although the myositis-specific autoantibodies are associated with distinct clinical presentations…
View details →Negative / Null Result ReportOpen accessMedicine
O'Connor LE, Thoerig RC, Leta CN et al. · 2026 · Advances in nutrition (Bethesda, Md.)
Infants may be exposed to contaminants from environmental and food sources, including human milk (HM) or infant formula (IF). The objective of this series of systematic reviews (PROSPERO: CRD42024530332, CRD42024530336, CRD42024530339, and…
View details →Failed Experiment ReportMedicine
Coello K, Stanislaus S, Forman JL et al. · 2025 · Free radical biology & medicine
Aims Increased oxidative stress-generated tissue damage seems to play a pivotal role in the pathophysiology and progression of bipolar disorder (BD). Malondialdehyde (MDA), a product of lipid oxidation, may represent a trait marker in BD…
View details →Failed Experiment Report
Mo X, Wen Q, Jiang C et al. · 2024 · Preprint
Abstract It was commonly accepted that adverse-risk acute myeloid leukemia patients should receive allogeneic hematopoietic stem cell transplantation (allo-HSCT) in first complete remission (CR1). In this multicenter study, we aimed to…
View details →Negative / Null Result ReportMedicine
Wade TD, Jabs M, Keegan E et al. · 2024 · The International journal of eating disorders
Objective We examine the small amount of research to date that describes and/or evaluates waitlist interventions as a precursor to treatment for an eating disorder (ED) with the intent to provide recommendations for future research that…
View details →Negative / Null Result ReportOpen accessMedicine
Contente J, Ferreira C, Silva M et al. · 2025 · Journal of bone and joint infection
Introduction : Debridement, antibiotics, and implant retention (DAIR) is recommended for early acute postoperative and late acute periprosthetic joint infections (PJIs). The KLIC and CRIME-80 scores have been proposed to predict DAIR…
View details →Negative / Null Result ReportMedicine
Li MS, Wu XQ, Zhou YJ et al. · 2024 · Ying yong sheng tai xue bao = The journal of applied ecology
Species range size is closely related to its ability to migrate and adapt to environmental change. Rapoport's rule predicts that species range size would become larger with increasing latitude or elevation. Empirical evidence for…
View details →Negative / Null Result ReportOpen accessMedicine
Rodriguez-Merchan EC · 2025 · The archives of bone and joint surgery
Periarticular multimodal drug injection (PMDI) is better than FNB (femoral nerve block) in pain relief after total knee arthroplasty (TKA). PMDI of bupivacaine [20 mL 0.5% bupivacaine hydrochloride - HCl (100 mg) following implantation…
View details →Negative / Null Result ReportMedicine
Weger HG, Polasek AK, Wright DM et al. · 2024 · The Journal of eukaryotic microbiology
Twenty species/isolates of cyanobacteria and green algae were isolated from cyanobacterial bloom samples in lakes associated with the upper Qu'Appelle River drainage system in southern Saskatchewan, Canada. Three amoebae species…
View details →Negative / Null Result ReportMedicine
Wiesenthal J, Schredl M · 2026 · Journal of sleep research
Although about 5% of the German population report having nightmares at least once a week, nightmares are inadequately diagnosed and treated. We therefore examined how people in the general population cope with nightmares in everyday life.…
View details →Negative / Null Result ReportMedicine
Stark BC, Alexander JM, Stockrahm E et al. · 2026 · American journal of speech-language pathology
Purpose This study examined the role of inner speech-defined here as the subjective experience of covert lexical access-in naming recovery following semantic feature analysis (SFA) treatment in individuals with aphasia. Specifically, it…
View details →Negative / Null Result ReportMedicine
Ercan P, Firlatan Yazgan B, Sendur SN et al. · 2026 · Pituitary
Purpose Long-term renal consequences of acromegaly remain poorly characterized. We assessed prevalence and independent predictors of renal cysts, chronic kidney disease (CKD), and the frequency of urinary-system malignancies, in a large…
View details →Negative / Null Result ReportMedicine
Swaid TK, Hamzeh LR, Bukasa LL et al. · 2026 · Intestinal research
Background/aims To determine time to diagnosis (TTD) and its impact on surgery and advanced therapy (AT) burden in inflammatory bowel disease (IBD) in a multi-ethnic United Arab Emirates (UAE) cohort, a region in the acceleration phase of…
View details →Negative / Null Result ReportOpen accessMedicine
Hajibandeh S, Hajibandeh S, Mckittrick H et al. · 2026 · World journal of gastrointestinal surgery
Background Early skeletal muscle wasting has been demonstrated to be associated with chemotherapy-related toxicity in patients with cancer. Hounsfield unit average calculation (HUAC) or psoas muscle index (PMI) can be used to diagnose…
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Kurasz Z, Krzyżowski M, Baran B et al. · 2026 · Preprint
Loneliness is increasingly prevalent in emerging adults and is theorised to engage threat-related biology that overlaps with nociceptive processing. We tested whether social connectedness and related cognitive-affective traits predict…
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Iler AM, CaraDonna PJ, Petry WK · 2026 · Preprint
Most plants require animal pollination to reproduce, prompting concern that pollinator declines immediately threaten plant populations. This concern is warranted if pollinator-mediated seed losses cause declines in plant population growth…
View details →Negative / Null Result ReportMedicine
Derégnaucourt S, Le Maguer L, Geberzahn N · 2026 · Animal cognition
Vocal learning in songbirds requires the integration of auditory perception, sensorimotor learning, and performance monitoring, yet its relationship to general cognitive abilities remains unclear. We tested whether interindividual…
View details →Negative / Null Result ReportMedicine
Guan M, Yang Q, Carey P et al. · 2026 · Health communication
Despite its significant implications for public health and individual decision-making, research on information avoidance remains limited. In this study, we applied and extended the model of planned risk information avoidance (PRIA) to…
View details →Negative / Null Result ReportMedicine
Wai KM, Parajuli RP, Umezaki M · 2026 · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS)
Telomeres are repetitive non-coding DNA sequences at chromosome ends that progressively shorten with each cell division, serving as markers of cellular aging. Recent studies have suggested that prenatal and postnatal exposure to…
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