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Browse the failure-mode index

21,742 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen accessMedicine

Longitudinal study of visual function in patients with relapsing-remitting multiple sclerosis with and without a history of optic neuritis

A. G. Gómez, A. García-Ben, A. S. García et al. · 2019 · Neurología (English Edition)

Abstract Introduction The contrast sensitivity test determines the quality of visual function in patients with multiple sclerosis (MS). The purpose of this study is to analyse changes in visual function in patients with relapsing-remitting…

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Negative / Null Result ReportOpen accessMedicine

Pulp Fibroblast Cell Apoptosis After Application of Hema Dentine Bonding Material with Ethanol and Water Solvent.

Ratih Elisa Nandarani, Ira Widjiastuti, Latief Mooduto · 2019 · Brazilian Dental Journal

The most common main materials for dentin bonding for composite resin restoration is 2-hydroxyethyl methacrylate (HEMA). HEMA has beneficial physical and chemical properties, and stable, yet toxic. The addition of ethanol or water, may…

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Negative / Null Result ReportOpen accessMedicine

Comparison of Retinal Nerve Fiber Layer Thickness Measurements in Healthy Subjects Using Fourier and Time Domain Optical Coherence Tomography

I. Pinilla, E. Garcia-Martin, M. Idoipe et al. · 2012 · Journal of Ophthalmology

Purpose. To compare the retinal nerve fiber layer (RNFL) measurements using two different ocular coherence tomography (OCT) devices: Cirrus Fourier domain OCT and Stratus time domain OCT. To analyze reproducibility of Fourier domain…

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Negative / Null Result ReportMedicine

Reverse Shoulder Arthroplasty for Patients with Cuff Tear Arthropathy: Do Clinical Outcomes Differ by Inlay versus Onlay Design?

Prashant Meshram, Piotr Łukasiewicz, Laurence Okeke et al. · 2024 · Journal of shoulder and elbow surgery

BACKGROUND The influence of position of the humeral tray (inlay or onlay) on clinical outcomes in reverse shoulder arthroplasty (RSA) is a topic of debate. The purpose of this study was to compare clinical and radiographic outcomes of…

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Negative / Null Result ReportOpen access

Contribution of the practice of resistance exercises and the type of delivery to the diastasis of the rectus abdominis muscles in primiparous women

F. Pacheco, Késsia Magalhães Espíndola, Jéssica Rosa Rezende et al. · 2023 · Fisioterapia e Pesquisa

ABSTRACT Maternal organism suffers physiological and biomechanical changes during pregnancy, including the separation of rectus abdominis muscles (RAM). This cross-sectional study aimed to compare the distance between the RAM among…

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Negative / Null Result ReportOpen accessMedicine

Retrospective Analysis of Chinese Patients with Hepatocellular Carcinoma (HCC) undergoing Transcatheter Arterial Chemoembolization (TACE) with or without Prophylactic Antibiotic Therapy.

Jiu Chen, Guolin Wu · 2018 · Journal of the College of Physicians and Surgeons--Pakistan : JCPSP

OBJECTIVE To assess the necessity of prophylactic antibiotic therapy in HCC patients undergoing transcatheter arterial chemoembolization (TACE). STUDY DESIGN Descriptive study. PLACE AND DURATION OF STUDY The First Affliated Hospital,…

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Negative / Null Result ReportOpen accessBiology

Genetic variation of the mitochondrial D-loop region containing mitochondrial transcription factor A (TFAM) binding sites is not associated with marbling in Wagyu × Limousin F2 crosses

T. Kunej, J. Michal · 2005 · Acta Agriculturae Slovenica

Mitochondrial transcription factor A (TFAM) is a nucleus-encoded protein that is essential for initiation of transcription and replication of mitochondrial DNA (mtDNA). It has been shown that TFAM binds the entire length of the mtDNA, but…

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Negative / Null Result ReportOpen accessMedicine

Creatine Enhances the Effects of Cluster-Set Resistance Training on Lower-Limb Body Composition and Strength in Resistance-Trained Men: A Pilot Study

D. Bonilla, R. Kreider, J. Petro et al. · 2021 · Nutrients

Creatine monohydrate (CrM) supplementation has been shown to improve body composition and muscle strength when combined with resistance training (RT); however, no study has evaluated the combination of this nutritional strategy with…

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Negative / Null Result ReportOpen accessMedicine

Lateral Pterygoid Muscle Biometric Modifications in Pterygoid Process Fractures Associated With Mandibular Fractures.

R. Nicot, Thomas Roland-Billecart, Alexandre Srouji et al. · 2020 · Journal of oral and maxillofacial surgery

PURPOSE Pterygoid process fractures (PPFs) are classically associated with Lefort fractures but can also be encountered in association with other facial fractures such as mandibular fractures. The aim of this study was to estimate the…

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Negative / Null Result ReportOpen accessMedicine

Multiple-dose versus single-dose gonadotropin-releasing hormone agonist after first in vitro fertilization failure associated with luteal phase deficiency: A randomized controlled trial

Danni Qu, Yuan Li · 2020 · Journal of International Medical Research

Objective To evaluate the efficacy and safety of multiple- versus single-dose gonadotropin-releasing hormone agonist (GnRH-a) addition to luteal phase support (LPS), in patients with a first in vitro fertilization (IVF) failure associated…

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Negative / Null Result Report

Stress level of nursing students at the clinical practicum in the University of Aguascalientes (Mexico)

Griselda-Paulina De-Lira-Padilla, Karen-Alondra Vallín-López, Violeta Compeán-Padilla et al. · 2025 · Frontiers in Education

Coping with stress is a process that involves a particular relationship between the individual and his/her environment. Nursing students are exposed to stressful situations during their practical training, due to the responsibilities they…

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Negative / Null Result ReportOpen access

Differences in expression of interleukin-6 and tumor necrosis factor-alpha fallopian tubes non-patent and fallopian tubes patent

U. R. Budihastuti, Abdurahman Laqif, Eriana Melinawati et al. · 2024 · Bangladesh Journal of Medical Science

Background: Fallopian tube infertility results from sexually transmitted infections and pelvic inflammatory diseases. The most common causes of infertility in women are infections caused by Chlamydia trachomatis and Neisseria gonorrhoeae.…

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Negative / Null Result ReportOpen accessMedicine

Postprandial changes in cardiometabolic disease risk in young Chinese men following isocaloric high or low protein diets, stratified by either high or low meal frequency - a randomized controlled crossover trial

A. Mok, S. Haldar, J. C. Lee et al. · 2015 · Nutrix Journal

BackgroundCardio-Metabolic Disease (CMD) is the leading cause of death globally and particularly in Asia. Postprandial elevation of glycaemia, insulinaemia, triglyceridaemia are associated with an increased risk of CMD. While studies have…

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Negative / Null Result ReportOpen accessMedicine

EFFICACY OF SILODOSIN VS TAMSULOSIN IN PATIENTS WITH BENIGN PROSTATIC HYPERPLASIA: A DOUBLE-BLIND RANDOMIZED CLINICAL TRIAL

S. T. C. Ariwicaksono, R. B. Prasetyo, Nindra Prasadja et al. · 2019 · International Journal of Applied Pharmaceutics

Objective: Benign prostatic hyperplasia (BPH) is a nonmalignant enlargement of the prostate associated with aging. BPH can cause lower urinary tract syndrome (LUTS). Medical therapy for patients with moderate and severe LUTS symptoms…

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Negative / Null Result ReportComputer Science

Can Modern NLP Systems Reliably Annotate Chest Radiography Exams? A Pre-Purchase Evaluation and Comparative Study of Solutions from AWS, Google, Azure, John Snow Labs, and Open-Source Models on an Independent Pediatric Dataset

Shruti Hegde, Mabon Ninan, Jonathan R. Dillman et al. · 2025 · arXiv.org

General-purpose clinical natural language processing (NLP) tools are increasingly used for the automatic labeling of clinical reports. However, independent evaluations for specific tasks, such as pediatric chest radiograph (CXR) report…

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Negative / Null Result ReportOpen accessMedicine

Dose escalation in radical radio(chemo)therapy for cervical and upper thoracic esophageal cancer with 3DCRT/IMRT (ChC&UES): a multicenter retrospective study

Xiao-han Zhao, Wencheng Zhang, Xin Wang et al. · 2024 · Radiation Oncology

Cervical and upper thoracic esophageal cancer (ESCA) presents treatment challenges due to limited clinical evidence. This multi-center study (ChC&UES) explores radical radio(chemo)therapy efficacy and safety, especially focusing on…

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Negative / Null Result ReportOpen accessMedicine

Three-year follow-up of changes of cortical bone thickness after implantation of Endo-Exo-Prosthesis (EEP) for transfemoral amputees

M. Örgel, E. Liodakis, Pratya Jaratjitwilai et al. · 2020 · Journal of Orthopaedic Surgery and Research

Introduction Transcutaneous Osseointegrated Prosthetic Systems (TOPS) offer a good alternative for patients who cannot be satisfactorily rehabilitated by conventional suspension sockets. The Endo-Exo-Prothesis (EEP, ESKA Orthopaedic…

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Negative / Null Result ReportOpen access

The Effect of Endoscopic Peritubal Adenoidectomy Vs Myringotomy with Ventilation Tubes Insertion in Management of Otitis Media with Effusion in Children

M. El Begermy, Marwa M El Begermy, H. Kassamy · 2022 · Egyptian Journal of Ear Nose Throat and Allied Sciences

Background: There is a lot of controversy about the role of adenoidectomy and myringotomy with ventilation tubes insertion (MVT) in management of otitis media with effusion (OME). In a previous study we found that endoscopic-assisted…

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Negative / Null Result ReportOpen access

Comparative evaluation of photoactivated disinfection and sonic irrigation as an adjunct to conventional irrigation on Enterococcus faecalis in root canals: An in vitro study

Tushar Kohli, N. Mehta, G. Garima et al. · 2021

Objective: The aim of the in vitro study was to compare the antibacterial efficacy of photoactivated disinfection (PAD), sonic irrigation as an adjunct to conventional irrigation against Enterococcus faecalis in vitro. Materials and…

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