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Browse the failure-mode index

21,742 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Motor coordination in school-aged children with different nutritional statuses following a non-immersive virtual reality intervention.

Da Silva Souza, De Souza, Dos Santos et al. · 2026 · Frontiers in public health

Children with low motor coordination tend to engage in less physical activity. They are more likely to gain weight, establishing a bidirectional relationship, as weight gain may further restrict their participation in physical activity.…

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Negative / Null Result ReportMedicine

Histopathological evaluation of local effects of radioactive iodine seeds in axillary lymph nodes in clinically node-positive breast cancer treated with neoadjuvant systemic therapy.

van Amstel, Simons, Kooreman et al. · 2026 · Breast (Edinburgh, Scotland)

In clinically node-positive (cN+) patients, radioactive iodine ( 125 I) seeds can be considered to mark metastatic axillary lymph nodes before neoadjuvant therapy (MARI-procedure) but potential therapeutic effects remain unclear. This…

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Negative / Null Result ReportMedicine

Effectiveness of transcranial direct current stimulation (tDCS) on attention and memory biases in individuals with post-traumatic stress disorder (PTSD): a randomized, single-blind, parallel-group study.

Estaji, Ahmadizadeh · 2026 · Journal of psychiatric research

Based on neurocognitive models, the development and maintenance of post-traumatic stress disorder (PTSD) are correlated with cognitive biases, including attention and memory biases, which are associated with imbalanced activation of…

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Negative / Null Result ReportMedicine

Tongue strength and endurance in relation to oral cavity morphology among children with Down syndrome in the permanent dentition period.

Maureen, Budiardjo, Wahono · 2026 · Journal of the Indian Society of Pedodontics and Preventive Dentistry

Down syndrome is a genetic condition caused by trisomy 21, often accompanied by orofacial hypotonia and anomalies in stomatognathic development. A hypotonic tongue may alter oral cavity morphology, particularly palatal depth, anterior…

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Negative / Null Result ReportMedicine

Amyotrophic Lateral Sclerosis: The State of the Art on Treatments and the Therapeutic Role of the Intestinal Microbiome in Human Studies.

Ptáček, Musil, Guarnieri et al. · 2026 · International journal of molecular sciences

Amyotrophic lateral sclerosis (ALS) is a common neurodegenerative disorder; to date, there is no long-term effective treatment. Recently, a relationship has been discovered between the human intestinal microbiome and the pathogenesis of…

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Negative / Null Result ReportMedicine

Sex Difference Has No Effect on Survival in Pancreatic Cancer.

Tas, Erturk · 2026 · Indian journal of surgical oncology

Due to controversial results, the clinical impact of sex in pancreatic cancer has not been fully clarified. We aimed to investigate the clinical significance of sex in patients with pancreatic cancer in this study. A total of 334…

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Failed Experiment ReportMedicine

Early onset radiation-induced leukoencephalopathy in patients treated for a glioblastoma by STUPP protocol and risk factors evaluation, an ancillary study of the phase III ASTER protocol.

Balcerac, Cuzzubbo, Bompaire et al. · 2026 · Revue neurologique

Since 2005, the standard treatment for newly diagnosed glioblastoma involves radiotherapy combined with concomitant and adjuvant temozolomide (TMZ), as per the Stupp protocol. A known long-term complication of radiotherapy is…

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Negative / Null Result ReportMedicine

Sleep and Haemophilia-A Case-Control Analysis of Associated Factors.

Schmidt, Brühl, Möllers et al. · 2026 · Haemophilia : the official journal of the World Federation of Hemophilia

Sufficient sleep is essential for maintaining both physical and mental health, yet data on sleep health among persons with haemophilia (PwH) remain limited. This study aimed to assess sleep in PwH compared to healthy controls (Con) and…

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