Negative / Null Result ReportOpen accessMedicine
Yasmin F, Rab AU, Asghar MS et al. · 2026 · Journal of cardiothoracic surgery
Purpose Given the systemic nature of connective tissue diseases (CTD), open surgical intervention for aortic stenosis is often considered high risk, making transcatheter aortic valve replacement (TAVR) a potentially preferable alternative.…
View details →Negative / Null Result ReportMedicine
Tomczyk K, Yang-Jensen KC, Lorentzen LG et al. · 2026 · Scientific reports
Prasterone (dehydroepiandrosterone, DHEA) is increasingly used in the treatment of genitourinary syndrome of menopause (GSM), although its molecular effects on vaginal tissue remain insufficiently characterized. This prospective study…
View details →Negative / Null Result ReportMedicine
Wen YC, Chu FY, Wang TH et al. · 2026 · Clinical toxicology (Philadelphia, Pa.)
Introduction Hydrogen sulfide exposure is a major cause of occupational poisoning and is frequently associated with life-threatening effects. This study aimed to investigate the patterns, poisoning severity, and predictors of severity in…
View details →Negative / Null Result ReportMedicine
Li Y, Qin L, Wang Y et al. · 2026 · Reproductive health
Background Menopausal age is closely associated with women's health, but research on its association with sarcopenia risk remains insufficient. Our study aimed to explore how menopausal age affects the risk of sarcopenia in postmenopausal…
View details →Negative / Null Result ReportMedicine
Kiracı M, Soytürk G, Köş FT et al. · 2026 · BMC cancer
Background Anthracyclines can induce endothelial and microvascular injury that precedes measurable myocardial dysfunction. However, reliable early markers of such injury are lacking. Nailfold capillaroscopy (NFC) is a noninvasive imaging…
View details →Negative / Null Result ReportMedicine
Virkkunen V, Kero K, Stenholm S et al. · 2026 · Menopause (New York, N.Y.)
Objectives For many women, retirement represents a significant transition in late adulthood, which may result in many alterations in lifestyle habits and behavioral patterns. Several factors known to improve during the retirement…
View details →Negative / Null Result ReportOpen accessMedicine
Woodworth E, Sheppard C, Wong R et al. · 2026 · Cureus
Background Following the transition to a single-accreditation residency system, Doctor of Osteopathic Medicine (DO) and Doctor of Allopathic Medicine (MD) students now apply for the same urology residency positions. Despite this…
View details →Negative / Null Result ReportMedicine
Swierkosz-Lenart K, Ranjbar S, Compagne C et al. · 2026 · The journal of ECT
Background Electroconvulsive therapy (ECT) is a widely used treatment for severe and treatment-resistant depression, with high efficacy but considerable interindividual variability of response. The neurophysiological mechanisms underlying…
View details →Negative / Null Result ReportMedicine
Barcaccia B, Cervin M, Borrelli DF et al. · 2026 · Journal of child psychology and psychiatry, and allied disciplines
Background Obsessive-compulsive symptoms (OCS) often emerge during childhood and adolescence, and two aetiological models have been proposed. According to the first model, maladaptive cognitive beliefs facilitate the transformation of…
View details →Negative / Null Result ReportOpen accessMedicine
Miculka A, Imhoff R · 2026 · International review of social psychology
Despite the social nature of generalized political attitudes such as conspiracy mentality, right-wing authoritarianism (RWA), and social dominance orientation (SDO), dyadic phenomena concerning these attitudes have not been comprehensively…
View details →Negative / Null Result ReportOpen accessMedicine
Wang Y, Li C, Zhang H et al. · 2026 · International journal for equity in health
BACKGROUND: Vision impairment is common among children and is known to affect learning, but its impact on children’s mental health has received less attention, especially in low- and middle-income countries. This study aims to focus on a…
View details →Negative / Null Result ReportMedicine
Gándara-Mireles JA, Reyes Espinoza EA, Loera-Castañeda V et al. · 2026 · Current issues in molecular biology
Doxorubicin (Dox) is a cornerstone in the treatment of pediatric acute lymphoblastic leukemia (ALL), but its use is limited by dose-dependent cardiotoxicity. Oxidative stress, arising from mitochondrial dysfunction, enzymatic generation of…
View details →Negative / Null Result ReportOpen accessMedicine
Szczupak M, Kobak J, Krupa-Nurcek S · 2026 · Frontiers in public health
Introduction Shift work is a recognized occupational risk factor for sleep disturbances, particularly among healthcare professionals. Nurses are especially vulnerable due to irregular work schedules, night duties, and the high physical and…
View details →Negative / Null Result ReportMedicine
Zhang Q, Yang T, Li L et al. · 2026 · Neurosurgical review
Chronic internal carotid artery occlusion (CICAO) is a significant cause of ischemic cerebrovascular events, with an annual stroke risk of up to 20%. Although the long-term efficacy of hybrid surgical revascularization (HSR) versus…
View details →Negative / Null Result ReportMedicine
Aslan T, AlShamrani M, Buck B et al. · 2026 · Stroke and vascular neurology
Background Stroke rates rise steeply with age but data on tenecteplase in patients ≥80 years remain limited. This post-hoc analysis of the AcT trial compared tenecteplase with alteplase in this population. Methods The analysis included all…
View details →Negative / Null Result Report
Peng M, Yuan Z, Lu Y et al. · 2026 · Preprint
Abstract Objective This study aims to investigate the effects of sleep disorders and cardiovascular disease comorbidity on the decade-long trajectory of memory function in middle-aged and elderly populations, thereby offering a scientific…
View details →Negative / Null Result ReportMedicine
Khan RB, Hanzlik E, Deokumar S et al. · 2026 · Pediatric blood & cancer
Background Hodgkin lymphoma is the most common cancer in adolescence and is treated with chemotherapy and/or radiation therapy. Little is known about neurologic symptoms, signs, and morbidity in long-term survivors of childhood Hodgkin…
View details →Negative / Null Result ReportMedicine
Qureshi S, Qureshi MA, Zehra SM et al. · 2026 · BMC cancer
Background Progastricsin/Pepsinogen C (PGC) is an aspartyl endoprotease predominantly expressed by gastric fundic and chief cells, with additional expression reported in select extragastric tissues. While increased PGC expression has been…
View details →Negative / Null Result ReportMedicine
Wang S, Miao J, Tang F et al. · 2026 · BMC cardiovascular disorders
Background The recurrence rate after ablation for atrial fibrillation (AF) remains high, and the predictive performance of existing predictors is limited. Left atrial dysfunction plays a key role in the occurrence and progression of AF.…
View details →Negative / Null Result ReportMedicine
Banerjee R, Kuruvilla C, Vega GL et al. · 2026 · The American journal of cardiology
While triglyceride-rich lipoproteins and small dense low-density lipoprotein (sdLDL) are associated with accelerated coronary atherosclerosis, their relationship with peripheral artery disease (PAD) is less clear. Fifty-five male subjects…
View details →Negative / Null Result ReportMedicine
Pyne AL, Uchida AM, Carlson M et al. · 2026 · Esophagus : official journal of the Japan Esophageal Society
Background Eosinophilic esophagitis (EoE) shares several risk factors with other autoimmune diseases, but population-based studies in this field are limited. Methods Using the Swedish nationwide histopathology cohort Epidemiology…
View details →Negative / Null Result ReportMedicine
Ding X, Wang Y, Choi M et al. · 2026 · Clinical oral implants research
Objective The objective of this study is to evaluate the clinical efficacy of angulated single-implant crowns using the hybrid retention versus pure screw-retained restorations in the aesthetic area. Materials and methods A retrospective…
View details →Negative / Null Result ReportMedicine
Yang H, Gao J, Mo S et al. · 2026 · European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
Objective and background The optimal surgical strategy for patients with hepatocellular carcinoma (HCC) and liver fibrosis/cirrhosis presenting with a future liver remnant to standard liver volume (FLR/SLV) ratio of 30%-40% remains a…
View details →Negative / Null Result ReportOpen accessMedicine
Süleyman S, Emin P, Hüseyin A et al. · 2026 · Journal of clinical medicine
Background/Objectives: Acute severe ulcerative colitis (ASUC) is a high-risk condition associated with intense inflammation and a substantial risk of early colectomy. Intravenous steroids (IVS) remain the first-line therapy; however,…
View details →Negative / Null Result ReportMedicine
Leizaola-Cardesa IO, Gómez-Moreno G, Hernando J et al. · 2026 · Journal of stomatology, oral and maxillofacial surgery
Background To determine serum parathyroid hormone (PTH), vitamin D, and calcium levels in patients with medication related osteonecrosis of the jaw (MRONJ), compared with patients receiving similar medication but without MRONJ; also, to…
View details →Negative / Null Result ReportMedicine
Darroudi S, Ghazaee H, Babaei N et al. · 2026 · Scientific reports
Empagliflozin, a sodium-glucose cotransporter-2 (SGLT2) inhibitor, has demonstrated cardioprotective effects beyond glycemic control. Empagliflozin has anti-inflammatory and antioxidant effects in long-term administration; however, current…
View details →Negative / Null Result ReportMedicine
Eslami M, Ermolaev N, Kronberger C et al. · 2026 · Scientific reports
Fibroblast growth factor 23 (FGF23), a bone-derived hormone, is emerging as a potential biomarker in cardiovascular disease. However, its role in transthyretin amyloid cardiomyopathy (ATTR-CM), a progressive infiltrative cardiomyopathy,…
View details →Negative / Null Result ReportOpen accessMedicine
Marković F, Bojić Z, Stjepanović M et al. · 2026 · Cancers
Background: Immune checkpoint inhibitor monotherapy targeting the PD-1/PD-L1 axis is a standard first-line treatment option for patients with metastatic non-small cell lung cancer (NSCLC) and high PD-L1 expression. However, comparative…
View details →Negative / Null Result ReportMedicine
Chow SCW, Wang Y, Leung OLK et al. · 2026 · Journal of autism and developmental disorders
Purpose This study investigated the risk of ASD and ADHD in children who have survived hypoxic-ischemic encephalopathy (HIE), one of the common conditions during birth resulting in neonatal brain injury. Methods A population-based cohort…
View details →Negative / Null Result ReportMedicine
Çakır B, Polat F, Karataş MB et al. · 2026 · Acta diabetologica
Background Diabetic cardiomyopathy (DCM) frequently begins with diastolic dysfunction (DD), which leads to increased left ventricular filling pressures and subsequent left atrial enlargement, quantified by the left atrial volume index…
View details →