e-ISSN: Pending

Browse the failure-mode index

21,742 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Abandoned Hypothesis

498 The Bristol Sign - A Technical Tip to Confirm Skin Flap Vascularity

Timothy Schrire, Ahmed Emam, Giulia Colavitti et al. · 2021 · British Journal of Surgery

Abstract Introduction In modern medicine, free flap reconstruction has become the gold standard when faced with soft tissue defects. The impressive cosmesis, and adaptability of free flaps means that we can securely state that we are in…

View details →
Negative / Null Result Report

USE OF MULTILOCAL MARKERS TO CONFIRM THE UNIQUENESS OF LEBEDYN CATTLE

N. В. Mokhnachova, O. M. Zhukorskyі · 2025 · Animal Breeding and Genetics

The aim of this study is to analyze the informativeness of ISSR markers in the study of intrapopulation genetic polymorphism of the Lebedyn local breed cattle population. Materials and methods of research. To confirm the uniqueness and…

View details →
Negative / Null Result Report

Abstract P1-14-07: Randomized phase 3 study of anthracycline-containing regimens versus S-1 as first-line treatment for metastatic breast cancer (SELECT BC-CONFIRM)–A combined analysis of two randomized phase 3 studies (SELECT BC-CONFIRM and SELECT BC)–

Y Park, H Akabane, T Watanabe et al. · 2019 · Cancer Research

Abstract Background: Anthracycline-containing regimens and taxane have been standard as the first-line chemotherapy for metastatic breast cancer (MBC). We conducted SELECT BC (randomized phase 3 study of taxane versus S-1 as first-line…

View details →
Negative / Null Result Report

The relative vitamin A value of 9‐cis‐ and 13‐cis‐β‐carotene did not differ in vitamin A‐depleted Mongolian gerbils

Kara Allison Bresnahan, Christopher Davis, Sherry Tanumihardjo · 2011 · The FASEB Journal

The provitamin A biofortification of staple crops is a novel approach to ameliorating vitamin A status in countries where deficiency is prevalent. To assess the vitamin A impact of these crops, the unique bioefficacies of cis‐isomers,…

View details →
Negative / Null Result Report

The first- or second-line use of pemetrexed sequentially with EGFR-TKI did not differ in PFS for advanced NSCLC patients harboring EGFR-mutant tumors.

Zhen-Yu Ding, Yue-Yun Chen · 2017 · Journal of Clinical Oncology

e20531 Background: Both EGFR-TKI and pemetrexed doublet chemotherapy (P) are two effective therapies in advanced NSCLC patients with EGFR mutant tumors. But which one should be used in first-line remains controversial. Methods: This was a…

View details →
Negative / Null Result Report

Nutritional Status of Water-soluble Vitamins Did not Differ According to Intake Levels of Wheat and Wheat Alternatives and Rice and Rice Alternatives as a Staple Food in Pregnant Japanese Women

Katsumi Shibata, Tsutomu Fukuwatari, Satoshi Sasaki · 2013 · Nutrition and Metabolic Insights

The objective of this study was to investigate whether the intake level of a staple food influences the nutritional status of water-soluble vitamins in pregnant Japanese women. Urinary excretion of water-soluble vitamins was used as a…

View details →
Negative / Null Result Report

Cooled feline intestine and fresh intestine did not differ in enterotomy leak pressure testing or in gross wall thickness measurement

Annellie K. Miller, Penny J. Regier, Federico R. Vilaplana Grosso et al. · 2024 · Veterinary Surgery

Abstract Objective To report gross anatomical gastrointestinal measurements and compare enterotomy leak pressures between fresh and cooled feline cadavers. Study Design Ex vivo, randomized study. Animals Fresh feline cadavers ( n = 20).…

View details →
Negative / Null Result Report

The effect of 0.5 mL mepivacaine administered as an abaxial sesamoid nerve block on lameness of horses with digital pain did not differ significantly from that of 2.5 mL of mepivacaine

Robert C. Cole, Fred J. DeGraves, Jessica Brown et al. · 2025 · American Journal of Veterinary Research

Abstract Objective To compare the effect of 2.5 mL 2% mepivacaine to the effect of 0.5 mL 2% mepivacaine administered over each palmar digital nerve, as an abaxial sesamoid nerve block (ASNB), to 6 horses lame because of naturally…

View details →
Negative / Null Result Report

Pain and Patient‐Reported Physical Function Did Not Differ Among Body Composition Profiles in Patients With Hip Osteoarthritis

Alexandra Ryan, Boliang Wang, Fiona Dobson et al. · 2026 · Arthritis Care & Research

Objective To explore whether higher body fat and lower lean mass are associated with greater pain and worse patient‐reported physical function in individuals with hip osteoarthritis (OA). A secondary aim was to examine whether pain and…

View details →
Negative / Null Result Report

Improvement in Long‐term Household Food Security among Indiana Households with Children did not Differ between Rural and Urban Counties after a Supplemental Nutrition Assistance Program‐Education Intervention

Rebecca L Rivera, Melissa K Maulding, Angela R Abbott et al. · 2016 · The FASEB Journal

Objective To determine the relationship of rural and urban county household status to long‐term food security among households with children in Indiana after a Supplemental Nutrition Assistance Program‐Education (SNAP‐Ed) intervention.…

View details →
Negative / Null Result Report

Clinical Outcomes of Follicular Thyroid Carcinoma Did Not Significantly Differ according to Tumor Size in an Iodine-Excessive Country

Da Eun Leem, Ji Hyun Yoo, Bo Ram Kim et al. · 2025 · Endocrinology and Metabolism

Background: Follicular thyroid carcinoma (FTC) measuring <2 cm is generally associated with good prognosis, while tumor size ≥4 cm is regarded as being associated with a poor prognosis. This study aimed to evaluate FTC prognosis by tumor…

View details →