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Browse the failure-mode index

21,742 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen accessMedicine

Successful weight loss maintenance in relation to method of weight loss

Angela Marinilli Pinto, A. A. Gorin, Hollie A Raynor et al. · 2008 · Obesity

This study examined the relation between method of weight loss and long‐term maintenance among successful weight losers enrolled in a weight‐loss maintenance trial. Participants were 186 adults (mean age = 51.6 ± 10.7 years, mean BMI =…

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Negative / Null Result ReportMedicine

Comparative Pathologic Analysis of Breast Cancers Classified as HER2/neu-Amplified by FISH Using a Standard HER2/CEP17 Dual Probe and an Alternative Chromosome 17 Control Probe

Somaye Y. Zare, Leo I. Lin, Abrar Alghamdi et al. · 2018 · American Journal of Surgical Pathology

At our institution, breast cancer cases that generate an equivocal HER2/neu (HER2) result by fluorescence in situ hybridization (FISH) using the dual HER2/chromosome enumeration probe (CEP17) are reflexed to an assay that utilizes an…

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Negative / Null Result ReportOpen access

Comparison of the effects of direct laryngoscopic and fiberoptic oral endotracheal intubation on the intraocular pressures of non-ophthalmic patients: A prospective, randomised, clinical trial

S. M., A. Ozkan, S. Akbaş et al. · 2022 · Annals of Medical Research

Aim: In this prospective, randomised, clinical study; we aimed to compare the effects of endotracheal intubation (ETI) via direct laryngoscope (DLS) and fiberoptic bronchoscope (FOB) on intraocular pressure (IOP) and haemodynamic data of…

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Negative / Null Result ReportOpen accessMedicine

Physical Activity and Sedentary Behavior in Children With Congenital Heart Disease

C. Voss, S. Duncombe, Paige H. Dean et al. · 2017 · Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease

Background Children with congenital heart disease (CHD) are thought to have low levels of physical activity (PA), but few studies have used objective measures of PA in this population. Methods and Results We recruited patients with mild,…

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Negative / Null Result ReportMedicine

Study on Normal Laryngeal Electromyography of Thyroarytenoid Muscle, Cricothyroid Muscle, and Posterior Cricoarytenoid Muscle

Xinlin Xu, Pan Yang, P. Zhuang et al. · 2018 · Annals of Otology, Rhinology and Laryngology

Objective: The aim of this study was to investigate the physiological activity of intrinsic laryngeal muscle under different functional states of larynx by measuring the normal laryngeal electromyography parameters. Methods: Laryngeal…

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Negative / Null Result ReportOpen accessMedicine

GlideScope® versus C-MAC®(D) videolaryngoscope versus Macintosh laryngoscope for double lumen endotracheal intubation in patients with predicted normal airways: a randomized, controlled, prospective trial

P. Huang, Renlong Zhou, Zhi-juan Lu et al. · 2020 · BMC Anesthesiology

Background The double lumen endotracheal tube (DLT) is the most widely-used device for single lung ventilation in current thoracic anesthesia practice. In recent years, the routine application of the videolaryngoscope for single lumen…

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Negative / Null Result ReportOpen accessMedicine

Discrepancies between leg-to-leg bioelectrical Impedance analysis and computerized tomography in abdominal visceral fat measurement

Hsueh-Kuan Lu, Yu-Ywan Chen, Chin-Jung Yeh et al. · 2017 · Scientific Reports

The aim of this study was to evaluate leg-to-leg bioelectrical impedance analysis (LBIA) using a four-contact electrode system for measuring abdominal visceral fat area (VFA). The present study recruited 381 (240 male and 141 female)…

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Negative / Null Result ReportOpen accessMedicine

Comparison of corneal changes after phacoemulsification using BSS Plus versus Lactated Ringer's irrigating solution: a prospective randomised trial

D. R. Lucena, M. S. Ribeiro, A. Messias et al. · 2010 · British Journal of Ophthalmology

Background/aims To compare two intraocular irrigating solutions, Balanced Salt Solution Plus (BSS Plus) versus Lactated Ringer's (Ringer), for the preservation of corneal integrity after phacoemulsification. Methods 110 patients undergoing…

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Negative / Null Result ReportMedicine

Effect of Volume on Postoperative Outcomes After Left Pancreatectomy: A Multicenter Prospective Snapshot Study (SPANDISPAN Project)

D. Aparicio-López, J. Ramia, C. Villodre et al. · 2025 · Journal of Clinical Medicine

Background/Objectives: Like many other countries, the management of pancreatic cancer in Spain has developed in a fragmented manner. This study analyzes clinical outcomes related to patient volume at different centers after left…

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Negative / Null Result ReportOpen accessMedicine

The Effect of Two Calcium Silicate Materials on the Fracture Strength of Simulated Immature Teeth during Regenerative Endodontic Treatment

H. Edrees, A. Y. Siddiqui, M. M. Almousa et al. · 2021 · Journal of Evolution of Medical and Dental Sciences

BACKGROUND Necrotic immature permanent teeth undergoing Regenerative Endodontic Treatment (RET) are subjected to functional forces that might lead to their fracture before achieving apical closure. This study compared the fracture strength…

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Negative / Null Result ReportMedicine

A Half-Century Review of Male and Female Resident Outcomes in Oral and Maxillofacial Surgery: A Single-Institution Report.

Susan Keefe, Carrie Baldwin, Elda Fisher et al. · 2025 · Journal of oral and maxillofacial surgery

BACKGROUND Limited comprehensive historical data exist comparing male and female residents in oral and maxillofacial surgery (OMS) residency programs. This gap underscores the need to examine sex-based differences to guide equitable…

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Negative / Null Result ReportOpen access

Entry Requirements as Predictors of the Academic Performance of Postgraduate Students in Universities in Zimbabwe

Norman Rudhumbu, Patience Kelebogile Mudau · 2022 · International Journal of Learning, Teaching and Educational Research

One of the major strategies that universities use to ensure quality in education is the use of entry requirements as a screening procedure to ensure that only those considered to be the ‘best’ students are admitted. Whether these so-called…

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Negative / Null Result ReportMedicine

The Effect of the Lateral First Metatarsal Head Shape on Hallux Valgus in Forced Turnout in Pre-Pointe Female Ballet Dancers: A Pilot Study.

Paul H Doan, David M Handojo, Shivani Parihar et al. · 2024 · Journal of the American Podiatric Medical Association (Print)

BACKGROUND A rounded lateral first metatarsal head shape is associated with higher rates of hallux abducto valgus recurrence following corrective surgery; however, the effect of the lateral first metatarsal head shape on the hallux…

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Negative / Null Result ReportOpen accessMedicine

A Benchmark Side-by-Side Comparison of Two Well-Established Protocols for in vitro Hematopoietic Differentiation From Human Pluripotent Stem Cells

F. Gutiérrez-Agüera, Virginia C. Rodríguez-Cortez, P. Petazzi et al. · 2021 · Frontiers in Cell and Developmental Biology

The generation of transplantable hematopoietic stem cells (HSCs) from human pluripotent stem cells (hPSCs) remains challenging. Current differentiation protocols from hPSCs generate mostly hematopoietic progenitors of the primitive…

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Negative / Null Result ReportMedicine

Which clinical factors and biochemical parameters differentiate major depressive disorder with versus without lifetime psychotic symptoms?

C. M. Esposito, F. Legnani, J. Barkin et al. · 2026 · International journal of psychiatry in clinical practice

OBJECTIVE Major depressive disorder (MDD) is a prevalent disabling condition, with psychotic features complicating its course and management. Purpose of the study is to identify clinical and biochemical factors differentiating psychotic…

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Negative / Null Result Report

Performance and Carass Potential of Pantaneiro Lambs Supplemented with Saccharomyces cerevisiae

Rafaela Machado dos Santos, Simone Fernanda Nedel Pértile, Marcos Barbosa Ferreira et al. · 2024 · Ensaios e Ciência: Ciências Biológicas, Agrárias e da Saúde

Abstract The aim of this study was to evaluate the effect of a feed additive for feedlot Pantaneiro lambs on weight gain, dry matter intake, carcass and meat characteristics, in addition to the comparison between males and females. Eleven…

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Replication FailureOpen access

Effect of feeding low protein diets supplemented with selected essential amino acids on growth performance and gut health in early weaned Large White Yorkshire piglets

N. Mohan, M. Dipu, K. Ally et al. · 2023 · Journal of Veterinary and Animal Sciences

A study was conducted to assess the effect of feeding low protein diets supplemented with selected amino acids on growth performance and gut health in early weaned Large White Yorkshire piglets. Thirty Large White Yorkshire female piglets…

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Negative / Null Result ReportOpen access

Association of β-Globin Gene Haplotypes with Haematological Parameters and Foetal Haemoglobin among Patients with Sickle Cell Disorder in Raipur, Chhattisgarh, India

S. Bhagat, A. Thakur · 2023 · Journal of Clinical and Diagnostic Research

Introduction: Sickle cell disease is caused by a single nucleotide substitution in the β-globin gene. The variations in Foetal Haemoglobin (HbF) levels, β-globin gene cluster haplotype have been used as predictors of disease severity in…

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Negative / Null Result ReportOpen accessMedicine

The Neonatal Congenital Anomalies: Incidence and Risk Factors Before and After the war at Al-Thawrah Hospital- Sana'a,Yemen.

F. M. Abol-Gaith, N. Ismail, A. Al-Mutawakel · 2019 · Assiut Scientific Nursing Journal

Background: Congenital anomalies (CAs) are structural or functional abnormalities that occur during intrauterine life and can be identified prenatally, at birth or may be detected in infancy later. Aim: To compare the incidence and risk…

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