Replication FailureMedicine
Eroğlu AS, Demirtaş OK · 2026 · Acta neurochirurgica
Objectives This study aims to retrospectively analyze the factors affecting implant failure in patients who underwent anterior cervical plating (ACP) following anterior cervical discectomy and fusion (ACDF). Methods Data from 332 patients…
View details →Failed Experiment Report
Kaur S, Shukla A, Gupta A et al. · 2026 · Preprint
Unlike the conventional mature neutrophils, immature neutrophils have been investigated for their regenerative properties; however, their limited availability necessitates alternative generation strategies. Here, we used a combination of…
View details →Negative / Null Result ReportMedicine
Ormancı N, Bölükbaş B, Waqas M et al. · 2026 · Biological trace element research
This study evaluated the metabolic and mineral profiles in the blood serum of Simmental dairy cows during the transition period to assess their energy, protein, and mineral status. A total of 78 cows from 10 farms in Samsun Province were…
View details →Negative / Null Result ReportOpen accessMedicine
Osipovė K, Maldonytė L, Lukšys D et al. · 2026 · Journal of clinical medicine
Background : The bond strength of orthodontic tubes to the enamel surface is essential for maintaining appliance stability, especially due to high masticatory forces on molars. Strong adhesion reduces the need for rebonding, shortening…
View details →Negative / Null Result ReportMedicine
Zuiderwijk M, Groene S, Lopriore E et al. · 2026 · Clinical and experimental pediatrics
Background Neonates born small for gestational age (SGA) are at an increased risk of multiple severe complications, including infections. This suggests that immune cells and other peripheral blood cells may be affected. Purpose Here we…
View details →Negative / Null Result ReportMedicine
Şengüllendi MF · 2026 · Journal of health organization and management
Purpose In recent years, the migration of healthcare professionals from developing countries to developed countries has accelerated. Türkiye is one of the countries negatively affected by the migration of healthcare professionals. This…
View details →Negative / Null Result ReportMedicine
Williams AE, Denaro K · 2026 · CBE life sciences education
Students often choose to study for exams with friends. Since active learning in class boosts success, instructors might expect studying with peers to also help. However, research offers little support for this. We investigated whether…
View details →Negative / Null Result ReportMedicine
Can MB, Kara A, Adigüzel MC et al. · 2026 · British poultry science
1. Following the ban on prophylactic antibiotic use in feed for poultry, interest in natural alternatives has increased, particularly plant-derived extracts. In this study, the effects of Aronia melanocarpa fruit extract (AMF) on growth…
View details →Negative / Null Result ReportOpen accessMedicine
Bregulla M, Packheiser J, Merz CJ et al. · 2026 · Scientific reports
Episodic memories can be shaped by various contextual factors. While social and sensory cues such as odors and music have been shown to influence encoding and retrieval, the role of tactile information remains unclear. In this…
View details →Negative / Null Result ReportOpen accessMedicine
Marinello WP, Zylka MJ · 2026 · Frontiers in toxicology
Introduction Per- and polyfluoroalkyl substances (PFAS), particularly perfluorooctanoic acid (PFOA), are persistent environmental contaminants known for bioaccumulation and adverse health effects, including neurodevelopmental toxicity.…
View details →Negative / Null Result ReportMedicine
Parhizmeymandi N, Azimi R, Sanjari MA et al. · 2026 · Motor control
Muscular fatigue often induces compensatory adjustments-such as increased motor unit recruitment and synchronization-that can elevate kinematic variability. By contrast, mental fatigue alters top-down neural control, modulates…
View details →Negative / Null Result Report
McGlynn M, Steffes LC, Shah A et al. · 2026 · Preprint
Pulmonary arterial hypertension is a progressive, fatal disease driven by pathologic vascular remodeling including arterial medial hypertrophy, occlusive neointimal lesion formation, and venous muscularization. Current vasodilatory…
View details →Negative / Null Result Report
Albanna RH, El-Farraj H, Awawdeh S et al. · 2026 · Preprint
Abstract Apical debris extrusion is an unavoidable phenomenon; however, evidence remains limited regarding the effect of newer motion kinematics, specifically counterclockwise optimum torque reverse (CCW OTR). Sixty-six mandibular molars…
View details →Replication FailureMedicine
Gkantidis N, Tsikouriadou E, Halazonetis D et al. · 2026 · Scientific reports
The present study investigated the association between facial shape and self-perceived personality and psychosocial traits. The study population consisted of 613 young adults (399 females and 214 males) aged 21-35 years, with similar…
View details →Negative / Null Result Report
Skondras EV, Kamalakidis SN, Skondra E et al. · 2026 · Preprint
Implant-supported overdentures improve denture retention and patient satisfaction, but debonding of attachment housings from the denture base remains a frequent prosthetic complication. This in vitro study evaluated the influence of…
View details →Negative / Null Result ReportMedicine
Belenger M, Dumont C, Geelhand P et al. · 2026 · Journal of speech, language, and hearing research : JSLHR
Purpose We investigated sex differences in the production of pauses in autistic (pre-)adolescents in two conversational contexts: a monologue and an interactive discussion. Method This study included 107 French-speaking participants ( M…
View details →Negative / Null Result ReportMedicine
Zhang M, Chai X, Zhang X et al. · 2026 · Annals of hematology
Chimeric antigen receptor T cells (CAR-T cells) have been widely applied in hematologic malignancies. It has shown limited efficacy in the treatment of myeloid neoplasms. We retrospectively analyzed the safety and efficacy of CD123 CAR-T…
View details →Negative / Null Result Report
Seeger J, Henke NA · 2026 · Preprint
Astaxanthin can be derived from different sources such as petrochemical synthesis, natural sourcing from green algae or by microbial fermentation. As one of the strongest antioxidants known by nature, astaxanthin is rising attention as an…
View details →Replication Failure
van der Linden C, Trapp P, Dembek TA et al. · 2026 · Preprint
Background Deep brain stimulation (DBS) of the ventral intermediate nucleus and posterior subthalamic area (VIM/PSA) in Essential Tremor (ET) and the subthalamic nucleus (STN) in Parkinson’s disease (PD) are established treatment for…
View details →Replication FailureMedicine
Webster E, Ng L, Prendergast K et al. · 2026 · Journal of insect physiology
Climate change and urbanisation are major drivers of global insect pollinator decline. However, the combined effects of these stressors remain poorly understood, particularly in relation to pollinator behaviour. Understanding how these…
View details →Replication FailureMedicine
Sheng YC, Chen X, Zhang YF et al. · 2026 · Huan jing ke xue= Huanjing kexue
Achieving ecological protection and high-quality development is the fundamental goal of sustainable development in the Yellow River Basin, and it is also an inevitable choice for the practice of the concept of Chinese-style modernization.…
View details →Replication FailureMedicine
Cheng WJ, Kao CL, Hung IY · 2026 · Frontiers in nutrition
Background Hearing impairment is associated with an elevated risk of depression, yet modifiable risk factors in this population remain poorly characterized. Although vitamin D deficiency (VDD) has been linked to depression in general…
View details →Negative / Null Result ReportMedicine
Szulim D, Kucharska E, Machalińska A et al. · 2026 · Nutrients
Background/Objectives : Age-related macular degeneration (AMD) is a leading cause of permanent deterioration of central vision in elderly people. While anti-VEGF therapy remains the standard of care for neovascular AMD, disease progression…
View details →Negative / Null Result ReportMedicine
Osorio-Vasco J, Rojas-Mora J, Barrera-Causil C et al. · 2026 · Work (Reading, Mass.)
BackgroundStanding work is common across a wide range of industries and service sectors and has been associated with the development of low back pain.ObjectiveTo analyze changes in low back pain across eight experimental scenarios…
View details →Negative / Null Result ReportMedicine
Suttles S, Boeth RR, Frazier M et al. · 2026 · Military medicine
Objective Describe an innovative Sports Medicine clinic design implemented in an outpatient Physical Therapy (PT) clinic within a Military Treatment Facility (MTF) for both referral and direct access (DA) entry portal pathways, and to…
View details →Negative / Null Result Report
Ramezani A, Rahimi S, Soltani A et al. · 2026 · Preprint
Abstract Background : Chronic pain is highly prevalent among older adults and has been shown to be associated with differences in cognitive function. While pain intensity reflects the severity of pain, pain interference assesses the extent…
View details →Negative / Null Result ReportMedicine
Yılmaz A, Kurt D · 2026 · BMC pregnancy and childbirth
Objective To evaluate systemic immune-inflammatory biomarkers in patients diagnosed with eclampsia and to investigate their potential association with inflammation. Methods This retrospective study included 31 patients with eclampsia and…
View details →Negative / Null Result Report
Chen G, Jiang L · 2026 · Preprint
Abstract How do contentious implementation processes reshape political trust in multi-level governance systems? This article examines this question through the case of land expropriation in China, a policy domain marked by visible local…
View details →Failed Experiment Report
Abdulrida FM · 2026 · Preprint
Abstract Background: The Hepatitis B (HBV) and Hepatitis C (HCV) viruses remain significant global health challenges, contributing to chronic liver disease and life-threatening complications. This study aimed to investigate the genetic…
View details →Negative / Null Result ReportMedicine
Henriques Cavalcanti Torres de Melo R, de Barros Silva PG, Neto HFEC et al. · 2026 · World journal of surgical oncology
Introduction Colorectal cancer (CRC) is one of the most prevalent malignancies worldwide, with up to 50% of patients developing metastatic disease, predominantly involving the liver. Hepatectomy remains the gold standard for resectable…
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