Negative / Null Result Report
de Barros B, Sultana F, Maximus N et al. · 2026 · Preprint
ABSTRACT Background Erythema nodosum leprosum (ENL) is a severe inflammatory complication of leprosy that often requires prolonged corticosteroid therapy which is associated with adverse effects. Methotrexate is an affordable…
View details →Negative / Null Result ReportMedicine
Garg AX · 2026 · Annals of internal medicine
Clinical impact ratings GIM/FP/GP: [Formula: see text] Critical Care: [Formula: see text] Nephrology: [Formula: see text].
View details →Negative / Null Result ReportMedicine
Dodd TS, Borzak S · 2026 · Annals of internal medicine
Clinical impact ratings GIM/FP/GP: [Formula: see text] Cardiology: [Formula: see text] Hematology: [Formula: see text].
View details →Negative / Null Result ReportMedicine
Jain S, Jha AK, Chawla D et al. · 2026 · Indian journal of pediatrics
OBJECTIVES: To determine the effect of prone positioning on the duration of respiratory support in neonates receiving non-invasive mode of ventilation. METHODS: This open label randomized controlled trial was conducted in the NICU of a…
View details →Negative / Null Result ReportOpen accessMedicine
Brasher MI, Patil MS · 2026 · Acta paediatrica (Oslo, Norway : 1992)
The LAKANA trial: a randomized control trial evaluating the impact of mass administration of azithromycin to infants 1 to 11 months of age in Mali showed no reduction in mortality.
View details →Negative / Null Result ReportOpen accessMedicine
Legnani C, Ventura A, Oriani G · 2026 · Journal of clinical practice and research
A retrospective study was conducted to evaluate the need for perioperative autotransfusions and the amount of blood loss by comparing patients receiving different tranexamic acid (TXA) regimens following total joint replacement (TJR). A…
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Holl CK, Bonilla Yanez M, Finley JM et al. · 2026 · Preprint
Background and Purpose Walking after stroke is often characterized by persistent biomechanical impairments and reduced walking capacity. While visual biofeedback can improve gait mechanics and fast walking can enhance capacity, it is…
View details →Negative / Null Result ReportMedicine
Greenway RR, Coulter AA, Zhang D et al. · 2026 · Journal of medicinal food
Gallic acid, a catechin polyphenol in tea, completely inhibited angiogenesis in assays of human tissue at 10 -3 M. Psoriasis is a skin disease caused by excessive secretion of angiogenenic factors by keratinocytes and stromal skin cells.…
View details →Negative / Null Result ReportMedicine
Fantasia ME, Penick CA · 2026 · Journal of economic entomology
Climate change intensifies drought frequency, posing risks to pollinators both directly and indirectly through changes in floral resource availability. We tested how water limitation alters pollinator-relevant floral traits, visitation,…
View details →Negative / Null Result Report
Kasige RH, Johnson SN, Frew A · 2026 · Preprint
Abstract Background and aims. Plant susceptibility to insect herbivores is shaped by interacting soil-based biotic and abiotic factors, particularly arbuscular mycorrhizal (AM) fungi and silicon (Si) availability. AM fungi influence plant…
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Ge H, Calero C, Costas R · 2026 · Preprint
Abstract Global scientific mobility is central to the circulation of knowledge, skills and opportunities, but its recent evolution remains unclear. Using the Dimensions database, we reconstruct publication-based career trajectories for…
View details →Negative / Null Result ReportMedicine
Rebel HG, de Gruijl FR · 2026 · Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology
We reported earlier that adult FabplCre;Apc 15lox/+ mice with either daily UV exposure or vitamin D supplementation developed not significantly fewer intestinal tumours but less tumour bulk (reduced outgrowth) than control mice that…
View details →Negative / Null Result ReportMedicine
De Grandi D, LuTheryn G, Stoffels M et al. · 2026 · Ultrasound in medicine & biology
Objective Dental biofilms are responsible for the majority of oral cavity diseases (e.g., caries, periodontitis and gingivitis). In this work, we evaluate the effects of therapeutic ultrasound on a Streptococcus mutans biofilm model. The…
View details →Negative / Null Result ReportMedicine
Uyoga MA, Baumgartner J, Malan L et al. · 2026 · The Journal of nutrition
Background Young South African women face a double-burden of overweight or obesity and iron deficiency, with the former predicting the latter. Omega-3 long-chain polyunsaturated fatty acid (LCPUFA) supplementation can reduce inflammation.…
View details →Negative / Null Result ReportMedicine
Lim LS · 2025 · Annals of internal medicine
Clinical impact ratings GIM/FP/GP: [Formula: see text] Cardiology: [Formula: see text] Geriatrics: [Formula: see text] Public Health: [Formula: see text].
View details →Negative / Null Result ReportMedicine
Pak MA, Güzel Altıntaş F, Okyar G et al. · 2026 · Scientific reports
Anastomotic leakage is a serious complication after colorectal surgery. Smoking is known to impair anastomotic healing. The use of electronic cigarettes is increasing worldwide, and information about their effects on wound healing remains…
View details →Negative / Null Result ReportMedicine
Amoroso F, Miere A, Kodjikian L et al. · 2026 · Retina (Philadelphia, Pa.)
Purpose This study aimed to compare exudative recurrence features detected by optical coherence tomography angiography (OCTA) with those identified by spectral domain optical coherence tomography (SD-OCT), considered the gold standard, and…
View details →Negative / Null Result ReportMedicine
Kalli AJ, Mäkelä P, Huhtala H et al. · 2026 · Acta anaesthesiologica Scandinavica
Background Sternotomy causes substantial postoperative pain. Recently, several less invasive nerve blocks have been described that are safer to use even on anticoagulated patients. This study aims to evaluate early pain management using…
View details →Negative / Null Result ReportMedicine
Quan S, Xie H, Zhang D et al. · 2026 · Esophagus : official journal of the Japan Esophageal Society
Background Postoperative chylothorax is a serious complication following esophagectomy. The efficacy of thoracic duct ligation (TDL) for chylothorax prevention is controversial. This study aimed to evaluate the impact of TDL on chylothorax…
View details →Negative / Null Result ReportMedicine
Osmani R, Cavallotto L, William N et al. · 2026 · Cryobiology
Cryopreservation of zebrafish embryos remains challenging due to their low tolerance for cryoprotectant exposure and their susceptibility to lethal ice formation. Ice recrystallization inhibitors (IRIs) such as…
View details →Negative / Null Result ReportMedicine
Wick B, Sahibzada O, Cherner A et al. · 2026 · Journal of vascular surgery. Venous and lymphatic disorders
Objective The optimal clinical management of isolated distal deep venous thrombosis (IDDVT) remains controversial as the benefits of routine anticoagulant therapy are not clearly defined amid the risk of bleeding events. Our study aimed to…
View details →Negative / Null Result ReportMedicine
Hetherington A, Bauer L, Rablin S et al. · 2026 · Australasian emergency care
Background Acute wheeze is a common emergency department presentation among pre-school aged children. Innovative models of care that safely optimise treatment and streamline patient flow are needed. A nurse-led stretching of inhaled…
View details →Negative / Null Result ReportMedicine
Agweyu A, Mwaniki P, Menon V et al. · 2026 · Nature medicine
Rigorous evidence on the performance of large language models (LLMs) in real-world, low-resource clinical settings remains limited. Here we conducted a pragmatic, cluster-randomized trial in 16 primary care facilities in Kenya. Clinical…
View details →Negative / Null Result ReportMedicine
Khan S, Simmons KL, Khan S et al. · 2026 · Orbit (Amsterdam, Netherlands)
Purpose To determine whether prophylactic antibiotic administration following the development of an orbital floor fracture or after orbital floor fracture repair is associated with a reduced risk of orbital or periorbital cellulitis.…
View details →Negative / Null Result Report
Connor V, Mitsi E, Cheliotis KS et al. · 2026 · Preprint
Nasopharyngeal colonisation with Streptococcus pneumoniae is a prerequisite for transmission and disease and represents an important immunising event. While colonisation induces serotype-specific immunity, the mechanisms underlying…
View details →Negative / Null Result ReportMedicine
Spotts EK, Chatterjee A, Coleman L et al. · 2026 · Psychology & health
Objective Informing individuals about the nocebo effect, termed nocebo education, can minimise the experience of side effects. One untested possibility is that nocebo education promotes behaviour change, such that it decreases the…
View details →Negative / Null Result ReportMedicine
Cheung LC, Mao F, Rydzak G et al. · 2026 · Annals of internal medicine
Background Cervical intraepithelial neoplasia (CIN) grade 2 (CIN 2) is an equivocal diagnosis of cervical precancer, and appropriate management continues to be debated. Objective To estimate the effect of immediate (by 6 months) versus…
View details →Negative / Null Result Report
Yu Q, Zeng L, Chen Z et al. · 2026 · Preprint
Abstract Fibroblast growth factor 23 (FGF23) is closely associated with atrial fibrillation (AF), yet whether it modulates sodium and calcium currents in atrial myocytes remains unclear. ETV1, a key transcription factor regulating atrial…
View details →Negative / Null Result ReportMedicine
Kam MK, Kim JW, Choi JY et al. · 2026 · Biochemical and biophysical research communications
Tau aggregation in neurons is a pathological hallmark of Alzheimer's disease (AD). The development of therapeutic drugs that inhibit tau aggregation in tauopathies, including AD, remains challenging. Herein, we developed a tau…
View details →Negative / Null Result ReportOpen accessMedicine
Lopez DE, Carmalt JL · 2026 · Frontiers in veterinary science
Background The equine temporomandibular joint (TMJ) is divided into two non-communicating joint (discotemporal DTJ and discomandibular DMJ) compartments. Ultrasound has been extensively used as a diagnostic tool in the horse, but previous…
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