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WASTE Journal

Browse the failure-mode index

21,294 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

The effectiveness of virtual reality in reducing preoperative anxiety among oral surgery patients under general anesthesia: a salivary stress biomarker and questionnaire-based study.

Yuza AT, Nurwiadh A, Hadikhrisna I et al. · 2026 · BMC oral health

Background Preoperative anxiety is a common psychological response to surgical operations affecting the emotional, cognitive and physiological state of the patient. It can be measured by both objective and subjective methods. While the…

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Negative / Null Result ReportMedicine

Craniofacial Growth and Hypodontia in Individuals Born with Van der Woude Syndrome.

Vesterbacka M, Parikakis K, Ganzer N et al. · 2026 · The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

ObjectiveTo study craniofacial growth and hypodontia in individuals born with Van der Woude syndrome (VWS) and compare with matched controls with and without a cleft.DesignA multicenter retrospective case-control study.SettingIndividuals…

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Negative / Null Result ReportOpen accessMedicine

Optical coherence tomography angiography evaluation of retinal and choriocapillaris changes after pars plana vitrectomy for macula-off rhegmatogenous retinal detachment: perfluoropropane versus silicone oil tamponade.

Karatepe MS, Erol YÖ · 2026 · BMC ophthalmology

BACKGROUND: Rhegmatogenous retinal detachment (RRD) with macular involvement may lead to persistent visual impairment despite successful anatomical repair. Different intravitreal tamponade agents used during pars plana vitrectomy (PPV) may…

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Negative / Null Result ReportOpen accessMedicine

Correlation of Scaphotrapezoid Contact Pressures With Degree of Trapezoid Resection: Does Eliminating Contact Matter?

Anz H, Roylance J, Ismaily S et al. · 2026 · Journal of hand surgery global online

Purpose Scaphotrapeziotrapezoid (STT) arthritis is the third most common hand arthritis in the United States. In the setting of thumb carpometacarpal arthroplasty, varying degrees of partial excision of the proximal trapezoid have been…

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Negative / Null Result ReportOpen accessMedicine

Differential spatiotemporal dynamics of cell wall-degrading enzymes underlie pathogenicity variation in two <i>Alternaria</i> species causing kiwifruit soft rot.

Ling LZ, Tai SH, Teng H et al. · 2026 · PeerJ

Kiwifruit soft rot caused by fungal pathogens can result in substantial postharvest losses. While Alternaria alternata and A. tenuissima have been implicated in this disease, their pathogenic mechanisms remain poorly characterized. This…

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Negative / Null Result ReportOpen accessMedicine

Instability of Oculomotor Control in Parkinson's Disease Without Freezing of Gait: Evidence From Reflexive and Voluntary Saccade Variability.

Daeinejad FS, Foumani MS, Behzadipour S et al. · 2026 · The European journal of neuroscience

Parkinson's disease (PD) is associated with alterations in both voluntary and reflexive eye movements; however, the characteristics of oculomotor variability across task contexts remain incompletely understood. This study investigated…

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Negative / Null Result ReportOpen accessMedicine

Osteogenic Differentiation Induced by Dental Pulp Stem Cells Secretome: A Dose-Dependent Comparative Study.

Kadkhodazadeh M, Amid R, Kheiri A et al. · 2026 · Clinical and experimental dental research

Objectives To investigate the effects of dental pulp stem cell-derived conditioned medium (DPSC-CM) on the proliferation, migration, and osteogenic differentiation of periodontal ligament stem cells (PDLSCs). Primary goals were to (i)…

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Negative / Null Result ReportMedicine

Comparison of Myringoplasty Outcomes Among External Auditory Canal Packing, Blood on the Graft Surface, or No External Auditory Canal Packing for Chronic Tympanic Membrane Perforation: A Randomized Study.

Lou Z, Yang H · 2026 · Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology

Objective The objective of this study was to compare graft outcomes and complications of myringoplasty among external auditory canal packing (EAC) with Nasopore, blood on the graft surface, and no EAC packing. Materials and methods…

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Negative / Null Result ReportMedicine

Diagnostic Performance of Diffusion-Weighted Imaging for Evaluation of Breast Lesions: Correlation With Prognostic Factors and Histological Phenotypes.

Konukoglu O, Kaya M, Arslan BC · 2026 · Journal of clinical ultrasound : JCU

Purpose To investigate the role of diffusion-weighted imaging (DWI) in the differential diagnosis of breast lesions and to determine whether there is an association with histological subtypes and prognostic factors. Materials & methods…

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Negative / Null Result ReportOpen accessMedicine

Effects of four weeks of inspiratory muscle training with different resistance modalities on pulmonary function and specialized athletic ability in synchronized swimmers: a randomised trial.

Xu H, Fan Y · 2026 · Scientific reports

This study applies resistance inspiratory muscle training to synchronized swimmers and through two resistance setting methods to explore that the differences in the effects of four weeks of dynamic constant load resistance training versus…

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Negative / Null Result ReportOpen accessMedicine

Impact of combined vascular resection on short and long-term results following radical surgery for hilar cholangiocarcinoma: evidence from a systematic assessment.

Che S, Saad SA, Wang Y et al. · 2026 · World journal of surgical oncology

OBJECTIVE: To analyze the impact of portal vein resection (PVR) and hepatic artery resection (HAR) on the short-term and long-term outcomes of patients with hilar cholangiocarcinoma after surgery. METHODS: A comprehensive literature search…

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Negative / Null Result ReportMedicine

The Coronal Lateral Collateral Ligament Sign Occurs Independent of Generalized Joint Hyperlaxity in Children and Adolescents With ACL-Deficient Knees.

Pedrick EG, Mitchell BC, Bomar JD et al. · 2026 · Journal of pediatric orthopedics

Background The lateral collateral ligament (LCL) sign is known to be correlated with greater anterior tibial translation (ATT) and internal tibial rotation in the setting of anterior cruciate ligament (ACL) tear. The LCL sign has also been…

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Negative / Null Result ReportOpen accessMedicine

β-Glucan training induces stimulus-dependent immune and metabolic modulation in head kidney leukocytes that persists for several days in Atlantic salmon (<i>Salmo salar</i> L.).

Nhan TH, Tort L, Lazado CC · 2026 · Frontiers in immunology

The innate immune system of fish has conventionally been considered incapable of immunological memory, but is now being recognised as exhibiting memory-like features known as trained immunity. This study investigated the induction of…

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Negative / Null Result ReportMedicine

Poller K-Wires versus Screws in Distal Tibial Nailing: Non-Inferior Union with Superior Efficiency and Better Alignment.

Yildirim AM, Bayram S, Karaçam MI et al. · 2026 · Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca

Purpose of the study To compare the short-term outcomes and complications of the poller screw (PS) and the poller K-wire (PW) in distal tibia nailing. Material and methods In the present study, a retrospective analysis was performed on…

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Negative / Null Result ReportOpen accessMedicine

The role of proinflammatory response and the kynurenine pathway in the association between childhood maltreatment and lifetime substance use disorder.

Östman L, Paul ER, Zhang H et al. · 2026 · Neurobiology of stress

Introduction Childhood maltreatment (CM) is a risk factor for adult psychiatric and substance use disorders (SUD). Retrospectively assessed CM has been linked to increased proinflammatory cytokines, including IL-6. Induced by inflammation,…

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Negative / Null Result ReportOpen accessMedicine

Efficacy of mesotherapy in patients with acute and subacute neck pain: A randomized controlled trial.

Gonultas D, Kulcu DG, Kaymaz EP et al. · 2026 · Turkish journal of physical medicine and rehabilitation

Objectives This study aims to investigate the effectiveness of mesotherapy in patients with acute or subacute neck pain compared to oral medications with the same active ingredients. Patients and methods In this randomized, single-blind…

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Negative / Null Result ReportOpen accessMedicine

Modulation of the gut microbiota as a novel strategy to prevent anastomotic leak after colorectal surgery: Systematic scoping review.

Helliwell JA, Sciberras P, Dosis A et al. · 2026 · Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

Background Anastomotic leak (AL) remains a major source of morbidity following colorectal surgery. Increasing evidence implicates the gut microbiome in the pathogenesis of AL, with certain microbial species disrupting tissue repair through…

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