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Browse the failure-mode index

21,294 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen accessMedicine

Short-term CoQ10 supplementation reduces markers of cardiac stress in soccer players following heavy exercise: A randomized double-blind placebo-controlled trial.

Rahimi MR, Morton AB, Golpasandi H et al. · 2025 · BMC sports science, medicine & rehabilitation

Background Coenzyme Q10 (CoQ10), a vital mitochondrial antioxidant, may enhance cardiovascular recovery and delay fatigue in athletes. This double-blind, randomized, placebo-controlled trial investigated CoQ10's effects on cardiac stress…

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Negative / Null Result ReportMedicine

Maternal Response to Therapeutic Plasma Exchange in Early Gestation: A Case Series of Thrombotic Microangiopathies and Neurological Disorders.

Karaaslan O, Türkyılmaz G, Hacıoğlu L et al. · 2026 · Biomedicines

Background/Objectives: Therapeutic plasma exchange (TPE) is an extracorporeal treatment used in thrombotic microangiopathies (TMAs) and various autoimmune and neurological disorders. However, data regarding its use during early pregnancy…

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Negative / Null Result ReportMedicine

Enhancing Immunity and Gut Microbiota Balance with Black Soldier Fly Larvae (BSFL) Meal: A Sustainable Feed Ingredient That Maintains Growth Performance in Pekin Ducks.

Long L, Liu G, Gao G et al. · 2026 · Insects

The effects of substituting soybean meal with black soldier fly larvae (BSFL) meal on the growth performance, immunological response, intestinal morphology, and gut microbiota of Pekin ducks were assessed. A total of 150 one-day-old Pekin…

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Negative / Null Result ReportOpen accessMedicine

The scramblase anoctamin 9 controls the immune response in lymphocytes.

Schreiber R, Ousingsawat J, Kunzelmann K · 2026 · Cellular and molecular life sciences : CMLS

We previously reported a loss of T cell activation following knockdown of the phospholipid scramblase and ion channel ANO9 (TMEM16J) in human Jurkat lymphocytes. We have now analyzed in detail the role of ANO9 in Jurkat ANO9 knockout cells…

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Negative / Null Result ReportMedicine

Factors influencing the sensory profile in patients with autism spectrum disorder from 16 months to 14 years: results of an observational study.

Marani N, di Gennaro D, Garotti R et al. · 2026 · Frontiers in psychiatry

Introduction Sensory processing abnormalities represent a high-impact clinical feature in individuals with Autism Spectrum Disorder (ASD). Sensory alterations can be classified by modality and behavioral responses to stimuli. The…

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Negative / Null Result ReportMedicine

Spondylolisthesis Reduction and Changes in Sagittal Alignment Following Single-Position Lateral Versus Lateral-Then-Prone Oblique Lumbar Interbody Fusion With Navigation-Assisted Posterior Percutaneous Instrumentation.

Ansari D, Bethel JA, Greeneway GP et al. · 2026 · Operative neurosurgery (Hagerstown, Md.)

Background and objectives Lateral interbody fusion represents a minimally-invasive approach to achieve indirect decompression via disc height restoration and alignment correction in patients with degenerative lumbar spondylolisthesis. If…

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Negative / Null Result ReportMedicine

Tunable self-association of partially dephosphorylated beta-casein

Rasmussen PL, Rinnan Å, Nielsen SB et al. · 2026 · Food Hydrocolloids.

The utilization of bovine casein for creating casein micelles with properties resembling those in human milk presents an opportunity to bridge the nutritional gap between human milk and infant formula. However, the processing of these…

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Negative / Null Result ReportMedicine

No Significant Impact of Preoperative Electrodiagnostic Testing on Short-Term Outcomes after Carpal Tunnel Release.

Williams AJ, Pum JM, Deyoung JK et al. · 2026 · The journal of hand surgery Asian-Pacific volume

Background: The purpose of this study was to compare Patient-Reported Outcomes Measurement Information System (PROMIS) Upper Extremity (UE) and PROMIS Pain Interference (PI) scores before and after carpal tunnel release (CTR) between…

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Negative / Null Result ReportMedicine

Mechanistic-statistical model for the expansion of ash dieback.

Fritsch C, Grosdidier M, Gégout-Petit A et al. · 2026 · Theoretical population biology

Hymenoscyphus fraxineus is an invasive forest fungal pathogen that induces severe dieback in European ash populations. The spread of the disease has been closely monitored in France by the forest health survey system which has made it…

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