Negative / Null Result ReportMedicine
Martinez-Canton M, Gallego-Selles A, Galvan-Alvarez V et al. · 2024 · Free radical biology & medicine
Calcium (Ca 2+ )/calmodulin-dependent protein kinase II (CaMKII) is activated during exercise by reactive oxygen species (ROS) and Ca 2+ transients initiating muscle contraction. CaMKII modulates antioxidant, inflammatory, metabolic and…
View details →Negative / Null Result ReportOpen accessMedicine
O'Leary RM, Zavlun N, Kinney A et al. · 2025 · Frontiers in psychology
Pupil dilation has become a well-established physiological index of cognitive effort. Here we examined the often-cited finding of an inverted U-shaped function of pupil size across the continuum from highly degraded to clear speech. Unlike…
View details →Negative / Null Result ReportMedicine
Funaki R, Nomura S, Ushima A et al. · 2024 · Biological & pharmaceutical bulletin
Commercially available so-called sanitizers in Japan are often touted as having remarkable "sanitizing (jokin)" effect, "virus-removal" capabilities, and "99.99%" removal rate of microbes and pathogens. In this study, we investigated the…
View details →Negative / Null Result Report
Bukhari SS, Saeed F, Tahir I et al. · 2023 · Preprint
Abstract Background: The standard of care for gliomas includes maximum safe resection of the tumor. This may lead to inadvertent damage to tissue directly or vasculature supplying normal brain tissue. This may result in perilesional brain…
View details →Negative / Null Result ReportOpen accessMedicine
Karra DA, Suchodolski JS, Newman SJ et al. · 2025 · Journal of veterinary internal medicine
Background Chronic enteropathies (CE) are common in cats, and alterations of the intestinal microbiota might be involved in the pathogenesis. Hypothesis/objectives To evaluate the efficacy of a single enema fecal microbiota transplantation…
View details →Negative / Null Result ReportMedicine
Rivera D, Robinson T, King AC · 2024 · Perceptual and motor skills
In this investigation, we examined the influence of two approaches of motor skill learning (differential learning and repetition-based) for an explosive motor skill. Twenty-seven individuals completed four training sessions of a standing…
View details →Negative / Null Result ReportOpen accessMedicine
Song M, Launder NH, Phutane VH et al. · 2026 · Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists
ObjectiveMajor depressive disorder (MDD) is a highly prevalent debilitating mental health disorder with a lifetime risk of 11-15% in Australia. The most effective treatment for severe depression is electroconvulsive therapy (ECT), but it…
View details →Negative / Null Result ReportOpen accessMedicine
Judith PJ, Maureen B, Mélanie P et al. · 2024 · Health science reports
Background In this study, we investigated whether the association of curcumin and docetaxel among advanced and metastatic breast cancer patients in first or second-line treatment potentiated the objective response rate. Patients/methods A…
View details →Negative / Null Result ReportMedicine
Thach B, Wang Y, Heng S et al. · 2024 · Placenta
Introduction The syncytiotrophoblast (STB) of the human placenta facilitates vital maternal-fetal communication and is maintained by fusion (syncytialization) of cytotrophoblasts. Serine protease HtrA4 (high temperature requirement factor…
View details →Negative / Null Result ReportOpen accessMedicine
Li M, Chen H · 2025 · BMC cardiovascular disorders
Background Eosinophilic myocarditis (EM) is a rare cardiac condition that is often difficult to diagnose. Although endocardial myocardial biopsy is considered the gold standard for diagnosis, sampling errors can lead to false-negative…
View details →Failed Experiment ReportOpen accessMedicine
Ma H, Yan Z, Gu R et al. · 2024 · Cancer immunology, immunotherapy : CII
Background Immunotherapy, such as chimeric antigen receptor T (CAR-T) cells targeting CD33 or CD123, has been well developed over the past decade for the treatment of acute myeloid leukemia (AML). However, the inability to sustain…
View details →Negative / Null Result Report
Valle AEPd, Hare M, Karley A et al. · 2026 · Preprint
Abstract Systems approaches are becoming widely recognised for their potential to address the complexity of food systems’ challenges and lead needed transformations. However, there is limited attention on how systems thinking is being…
View details →Negative / Null Result ReportMedicine
Zahl-Olsen R, Gausel N, Håland ÅT et al. · 2026 · Journal of clinical psychology
Routine Outcome Monitoring systems have been developed to monitor how clients' lives change over the course of therapy. However, for such systems to be effective, they must possess sufficient construct validity and scale-reliability to…
View details →Negative / Null Result Report
Ito R, Okanoya K · 2026 · Preprint
Octave equivalence—the tendency to perceive tones separated by a 2:1 frequency ratio as perceptually similar—is a fundamental feature of human pitch perception and a key component of musical pitch organization. Evidence for octave…
View details →Failed Experiment Report
Kelso ZS, Snyder MC, Gershman SJ · 2026 · Preprint
Planarian flatworms represent one of the most evolutionarily informative nervous systems for an account of ancient bilaterian brains. Likewise, the unparalleled regenerative ability of planarians makes possible certain investigations of…
View details →Negative / Null Result ReportMedicine
Singh S, Jagannathan K, Childress AR et al. · 2026 · European eating disorders review : the journal of the Eating Disorders Association
Objective Weight suppression (WS), or the difference between one's highest past and current weights, may help maintain bulimia nervosa (BN) by altering reward response to food cues. This pilot study tested associations among WS, brain…
View details →Negative / Null Result ReportOpen accessMedicine
· 2006
The effects of maternal alcohol (ethanol) ingestion during lactation are complex and depend on the pattern of maternal drinking. With casual alcohol use (such as 1 glass of wine or beer) it is best to wait 2 to 2.5 hours per drink before…
View details →Negative / Null Result ReportMedicine
Gámez Martínez S, Lovatón Romero G, Alcañiz Raya M et al. · 2026 · Cyberpsychology, behavior and social networking
The diagnosis of autism spectrum disorder is based on clinical judgment, as there are no clearly identified markers to determine the presence of this condition. Gaze patterns have been proposed as a potential biomarker for autism. This…
View details →Negative / Null Result ReportMedicine
Knight KF, Milton F, Zeman A · 2026 · Neuropsychologia
Visual mental imagery and visual working memory are often thought to be closely related. After all, both have been argued to involve the temporary maintenance of visual representations in conscious awareness. We might expect, therefore,…
View details →Negative / Null Result ReportMedicine
Randa L, Lee C, Cheng J et al. · 2026 · Journal of electrocardiology
Background The frequency of cardiac ectopy, including premature atrial contractions (PACs), premature ventricular contractions (PVCs), non-sustained supraventricular tachycardia (SVT), and non-sustained ventricular tachycardia (NSVT), is…
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Koß C, Blanke JH, de la Cuesta-Ferrer L et al. · 2026 · Preprint
Signal detection theory posits that subjects in two-stimulus, two-choice discrimination tasks decide by comparing random samples of an evidence variable to a static decision criterion. While the core assumptions of the theory have received…
View details →Negative / Null Result ReportMedicine
Cuspidi C, Facchetti R, Tadic M et al. · 2026 · Journal of hypertension
Background The long-term reproducibility of the nighttime blood pressure (BP) phenotypes, namely, dipping (D) and nondipping (ND) has never been described in population-based studies. We investigated this issue in the participants to the…
View details →Negative / Null Result ReportMedicine
Lu S, Efendić E, Feldman G · 2025 · Journal of personality and social psychology
The appraisal-tendency framework proposed that specific emotions predispose individuals to appraise future events corresponding to the core appraisal themes of the emotions. In a registered report with a U.S. American online Amazon…
View details →Negative / Null Result ReportMedicine
Kurian C, Kurian E, Orhurhu V et al. · 2026 · Regional anesthesia and pain medicine
Background While many medical specialties have established links between bibliometric indices, academic rank, leadership roles, and National Institutes of Health (NIH) funding, there exists a gap within the field of pain medicine. The…
View details →Negative / Null Result Report
Mirpour K, Alijanpourotaghsara A, Pouratian N · 2025 · Preprint
Abstract Parkinson’s disease (PD) involves progressive neurodegeneration and distinctive structural and functional alterations in cortico-basal ganglia circuits. This study proposes bridging the gap between structural and functional…
View details →Negative / Null Result ReportMedicine
Ntoumenopoulos G, Hansell L, Neindre AL et al. · 2026 · Australian critical care : official journal of the Confederation of Australian Critical Care Nurses
Background The extent of pulmonary aeration present on admission to the intensive care unit (ICU) as determined by the lung ultrasound score (LUSS) may be useful to predict weaning from mechanical ventilation. The aim of this study was to…
View details →Negative / Null Result ReportMedicine
Harris KM, Curby TW, Goldston DB et al. · 2026 · Psychological services
Rates of adolescent psychiatric hospitalization have increased significantly over the last decade. Despite heightened risk for life-threatening behavior and readmission in the year following hospitalization, mental health service use has…
View details →Negative / Null Result ReportMedicine
Acevedo L, Fernández-Sarmiento J, Mulett H et al. · 2026 · Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies
Objectives To compare survival, clinical characteristics, complications, and duration of extracorporeal membrane oxygenation (ECMO) support in pediatric patients with severe adenoviral respiratory infections vs. those with other viral…
View details →Negative / Null Result ReportMedicine
Dvořáková M, Chládková K · 2025 · Journal of speech, language, and hearing research : JSLHR
Purpose The mismatch negativity (MMN), a neural index of speech sound discrimination, is reportedly stronger for phonemically relevant speech sound differences than for phonemically irrelevant differences, even if the former are…
View details →Negative / Null Result Report
Zenkov VS, Cockburn IA, Lin R et al. · 2025 · Preprint
A relatively small number of liver-localized CD8 T cells can provide sterilizing protection against exposure to Plasmodium sporozoites. Previously published mathematical model-based simulations of randomly searching for an infection T…
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