21,713 real negative results, null findings, and replication failures. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Nam J, Bellinger GC, Li J et al. · 2025 · JMIR cardio
Background Wearable activity monitors offer clinicians and researchers accessible, scalable, and cost-effective tools for continuous remote monitoring of functional status. These technologies can complement traditional clinical outcome…
View details →van Berlo E, Hausfeld J, Engelmann JB et al. · 2024 · Preprint
In this study, we investigated how spatial, temporal, and effort dimensions collectively influence reward discounting across different age groups. Using a 3D simulated environment, participants aged 7 to 77 chose between a nearby tree with…
View details →Angeletos Chrysaitis N, Seriès P · 2024 · Preprint
Bayesian studies of perception have documented how the brain learns the statistics of a new environment and uses them to interpret sensory information. Impairments in this process have been hypothesised to be central to autism spectrum…
View details →Liu X, Zheng W, Hoon L et al. · 2026 · Npj mental health research
Smartphone-delivered interventions offer a scalable solution for university students experiencing depression, yet outcomes remain inconsistent. This study examined predictors of depression remission and response in the AI-enhanced Vibe Up…
View details →Bakhshinejad JA, Watkins CM, Pelton LM et al. · 2026 · International journal of exercise science
The primary aim of this investigation was to examine the effects of three drop jumps (DJ) on mean velocity (m/s) of subsequent deadlifts at various percentages of 1 RM. A secondary exploratory aim was to evaluate whether protocol order,…
View details →Lewandowski KE, Luo J, Yao B et al. · 2025 · Frontiers in psychiatry
Introduction Motivational impairments are a hallmark symptom of psychotic disorders. However, motivation is a multidimensional construct believed to be underpinned by different neural mechanisms and differentially impaired both between and…
View details →Cronin SK, Barnard AM, Dietz SJ et al. · 2023 · Journal of dairy science
It is possible that some of the systemic responses to subacute ruminal acidosis (SARA) may be caused by increased intestinal starch fermentation. The objective of this experiment was to evaluate the effect of abomasal infusion of up to 3 g…
View details →He JD, Parker JD · 2023 · British journal of clinical pharmacology
Aims To mediate its pharmacodynamic effects, glyceryl trinitrate (GTN) requires bioactivation, by which it releases nitric oxide or a nitric oxide moiety. The exact mechanism of GTN bioactivation remains uncertain. Mitochondrial aldehyde…
View details →Alizo Vera V, Childs JE, Kim J et al. · 2025 · eNeuro
Histone deacetylase 3 (HDAC3) is one of the most highly expressed HDACs in the brain shown to be a negative regulator of long-term memory formation. HDAC3 has also been shown to be involved in cocaine-associated behaviors, demonstrated by…
View details →Sabino-Carvalho JL, Li S, Mekonnen E et al. · 2025 · Medicine and science in sports and exercise
Purpose Parasympathetic reactivation is essential for the rapid decrease in heart rate following exercise and delayed heart rate recovery (HRR) post-exercise is linked to poor clinical outcomes. Chronic kidney disease (CKD) is associated…
View details →Volpe LJ, Zugelder M, Kotarinos R et al. · 2023 · Urogynecology (Philadelphia, Pa.)
Importance Although pelvic floor physical therapy (PFPT) is effective in treating high-tone pelvic floor dysfunction (HTPFD), data on the mechanism of improvement are limited. Objectives This study aimed to compare squeeze intravaginal…
View details →Hill E, Harleman M, Harris L et al. · 2024 · Environmental Research
Traffic-related air pollution (TRAP) poses a significant public health risk that is associated with adverse birth outcomes. Large roadway infrastructure projects present a natural experiment to examine how resulting congestion change is…
View details →Alper S, Toribio-Flórez D, Capraro V et al. · 2024 · Preprint
Conspiracy theories assert that others have engaged in dishonest actions. However, existing research indicates that individuals who believe in conspiracy theories may themselves be more inclined to engage in dishonest behavior. We…
View details →Martin EA, Kim SB, Beckham GK et al. · 2025 · Journal of functional morphology and kinesiology
Objectives The objective of this study was to examine the neuromuscular fatigue response to playing in a singles pickleball tournament, as measured by performance on a countermovement jump test (CMJ). We hypothesized that players would…
View details →Goh R, Ng F, Bacchi S et al. · 2025 · Cerebrovascular diseases extra
Introduction We aimed to determine whether relative hypotension, defined as a systolic blood pressure (SBP) threshold of 0.318) during anterior circulation large-vessel occlusion (LVO) acute ischaemic stroke (AIS). Methods In a…
View details →O'Sullivan S, Bolland M, Cundy T · 2025 · JBMR plus
In a 2015 study of SQSTM1 mutation carriers who had initial negative bone scintigraphy, we found that the rate of development of Paget's disease of bone (PDB) over 5 yr was low. We report here an additional 8-yr follow-up of this cohort,…
View details →Fiala MA, Ji M, Slade M et al. · 2026 · JCO oncology practice
Purpose This study aimed to determine if high-deductible health plan (HDHP) enrollment contributes to financial burden and hinders access to care for patients with multiple myeloma (MM). Materials and methods Patients diagnosed with MM…
View details →Shoji T, Kogure K, Toda N et al. · 2025 · Geriatrics (Basel, Switzerland)
Background/Objectives : In Japan, the number of older patients with diabetes mellitus (DM) is rapidly increasing; however, the impact of DM on higher-level functional capacity in this population is unclear. In this study, we aimed to…
View details →Shariffi B, Harper JL, McMillan NJ et al. · 2025 · American journal of physiology. Heart and circulatory physiology
Insulin has important vasodilatory effects in the peripheral circulation, but less is known about insulin's role in cerebrovascular control. Herein, we hypothesized both systemic (intravenous) and local (intranasal) insulin administration…
View details →Perry D, Lino H, Bertschy M et al. · 2024 · Preprint
Background Advanced footwear technology has become commonplace in the competitive running world. However, a systematic exploration of the effects of each of the primary components has not yet been presented. Purpose To quantify running…
View details →Chakraborty AK · 2024 · Preprint
Abstract We postulated a higher omicron JN.1/BA.2.86.1.1 coronavirus transmission due to unique 17 MPLF spike insertion compensating 24 LPP, 69 HV, 145 Y, 211 N and 483 V deletions [Journal of Future Medicine and Healthcare Innovation,…
View details →Sahoo D, Acharya S · 2025 · Biology open
To assess metabolic depression and non-specific immune response during hibernation in male common Asian toads, Duttaphrynus melanostictus, we measured activities of different enzymes of both aerobic (oxygen-dependent) and anaerobic…
View details →Rogers CW, Crisp A, Wilhite K et al. · 2026 · The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association
Background Physical activity (PA) during pregnancy has well-documented benefits, yet pregnant rural residents may face additional barriers to PA. Objective To examine whether leisure-time physical activity (LTPA) and correlates of LTPA,…
View details →Seetahul Y, Greitemeyer T · 2024 · Preprint
Objective: With two experiments (N = 1,576), we examine the causal effect of frustration on the immediate inclination to play violent video games (VVGs) and the moderating role of long-term VVG exposure. Method: Frustration was…
View details →Taherzadeh Z, Kissell CE, Young BE et al. · 2025 · American journal of physiology. Regulatory, integrative and comparative physiology
Non-Hispanic Black (BL) adults living in the United States are more likely to develop cardiovascular disease (CVD) compared with their non-Hispanic White (WH) counterparts. Although measures of cardiac autonomic function [i.e., spontaneous…
View details →Seetahul Y, Greitemeyer T · 2024 · Preprint
Objective: With two experiments (N = 1,576), we examine the causal effect of frustration on the immediate inclination to play violent video games (VVGs) and the moderating role of long-term VVG exposure. Method: Frustration was…
View details →Iwabuchi T, Hirai T, Umeda N et al. · 2025 · Autism research : official journal of the International Society for Autism Research
Recent studies have implicated oxidative stress in the pathophysiology of autism spectrum disorder (ASD). Postmortem brain studies have revealed decreased levels of the reduced form of glutathione (GSH), an important antioxidant, in some…
View details →Ihsan Kahveci, Timothy A. Thomas, Nathalie E. Williams et al. · 2026 · arXiv
Home eviction poses a significant threat to housing stability, a critical determinant of health. This study examines the relationship between eviction and health and substance use within the unhoused population of King County, Washington. Using a sample of 1,106 individuals experiencing homelessness, we employed a quasi-experimental design to compare the health outcomes of those who have experienced eviction with those who have not. Our findings reveal eviction is associated with an 8.3% point increase (SE = 0.039) in the likelihood of reporting poor general health and an 9.5% increase (SE = 0
View details →Maximilian Warsinke, Maurizio Vergari, Tanja Kojić et al. · 2025 · arXiv
This study explores how prior exposure to physical objects influences the quality and realism perception of Digital Twins (DT) with varying levels of fidelity in Virtual Reality (VR). In a mixed experimental design, 24 participants were divided into two equal groups: an exposure group, in which members were shown physical objects before inspecting and rating their replicas in VR, and a control group without prior knowledge. Three objects were presented, each under four fidelity conditions with varying texture resolution and geometric detail. Participants rated perceived quality and realism thr
View details →Rahul Arora, Jiannan Li, Gongyi Shi et al. · 2021 · arXiv
Size and distance perception in Virtual Reality (VR) have been widely studied, albeit in a controlled laboratory setting with a small number of participants. We describe a fully remote perceptual study with a gamified protocol to encourage participant engagement, which allowed us to quickly collect high-quality data from a large, diverse participant pool (N=60). Our study aims to understand medium-field size and egocentric distance perception in real-world usage of consumer VR devices. We utilized two perceptual matching tasks -- distance bisection and size matching -- at the same target dista
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