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Browse the failure-mode index

21,283 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result Report

Influence of Patient-Related Factors and Surgeon Experience on Functional Outcomes in Conservatively Treated Proximal Humerus Fractures: A Retrospective Cohort Study

Pautasso A, Bernardi C, Assom M et al. · 2026 · Preprint

Abstract Purpose Proximal humerus fractures (PHFs) are common in the elderly population, but the optimal treatment strategy remains controversial. This study evaluated long-term functional outcomes of conservatively treated PHFs and…

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Negative / Null Result ReportMedicine

Assessing the Effectiveness of Multidisciplinary Interventions in Reducing Catheter-Associated Urinary Tract Infection: An Interrupted Time Series Modeling Approach.

Wills W, Rosever K, Bugajski A et al. · 2026 · Journal of nursing care quality

Background Recommendations support multi-interventional catheter-associated urinary tract infection (CAUTI) reduction programs; however, identifying specific interventions with significant impact may be beneficial in resource-limited…

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Negative / Null Result ReportMedicine

Exploring the Mediating Role of Social Media and Gaming in the Relationship between Adolescents' Feelings of Loneliness, Ostracism and Internalizing and Externalizing symptoms.

Bruneel S, Sjöblom J, Lagerström M et al. · 2026 · Child psychiatry and human development

Social outsiderhood - particularly loneliness and ostracism - has a significant impact on mental health issues such as internalizing symptoms (e.g., depression, anxiety) and externalizing symptoms (e.g., aggression, conduct problems). Yet,…

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Negative / Null Result ReportMedicine

Evaluation of rotational profile and foot loading in the uninvolved leg of children with unilateral clubfoot treated with foot abduction orthoses.

Lawing CR, Bailey CE, Garg S et al. · 2026 · Journal of pediatric orthopedics. Part B

Ponseti treatment of congenital clubfoot utilizes foot abduction bracing to prevent recurrence. In unilateral clubfoot, families have expressed concern about inducing deformity in the uninvolved leg. This study evaluated rotational…

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Negative / Null Result ReportMedicine

Impact of the COVID-19 pandemic on pediatric hemolytic uremic syndrome: Epidemiology, complications, and outcomes.

Jarosz-Wójcik E, Zajączkowski MA, Drożdż D et al. · 2026 · Advances in clinical and experimental medicine : official organ Wroclaw Medical University

Background Hemolytic-uremic syndrome (HUS) is a thrombotic microangiopathy that is most commonly caused by infection with Shiga toxin-producing Escherichia coli (STEC-HUS). Atypical HUS (aHUS) is associated with inappropriate activation of…

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Failed Experiment ReportMedicine

Impact of a home-based obesity prevention intervention on children's eating behaviours: Findings from the Guelph Family Health Study randomised controlled trial.

Jacob R, Walton K, Buchholz AC et al. · 2026 · Appetite

Children's eating behaviours are important determinants of childhood obesity; however, few studies have examined whether early childhood obesity prevention interventions influence these behaviours. This study investigated the impact of a…

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Negative / Null Result ReportMedicine

Effect of a multifaceted hospital fluid conservation approach to intravenous fluid shortages on patient outcomes.

Xu O, Graven P, Downs S et al. · 2026 · American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists

Purpose In September 2024, Hurricane Helene disrupted a key North Carolina facility producing 60% of medical-grade fluids in the United States, causing a nationwide intravenous fluid (IVF) shortage and prompting urgent conservation in…

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Negative / Null Result ReportMedicine

Effect of Basal Septal Hypertrophy on TAVR Outcomes: Evidence From a Large Cohort Study.

Arow Z, Oliva O, Iwata J et al. · 2026 · Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions

Background Basal septal hypertrophy (BSH) is commonly encountered in elderly patients undergoing transcatheter aortic valve replacement (TAVR). However, its impact on periprocedural and procedural outcomes remains unclear. Aims The aim of…

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Negative / Null Result ReportMedicine

Improving Medication Adherence in Kidney Transplant Recipients Through Educational Intervention and Monitoring: A Randomized Clinical Trial.

Heinrich de Oliveira C, Schweig A, Gonçalves BP et al. · 2026 · Transplantation proceedings

Background Kidney graft survival after transplantation is highly dependent on continuous adherence to immunosuppressive therapy. Poor adherence is a significant cause of graft loss, and educational interventions to optimize care have been…

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Negative / Null Result ReportOpen accessMedicine

The association between sleep quality and postoperative pain after half-impacted mandibular third molar extraction: comparison of three statistical models.

Hu L, Zhao C, Wang T et al. · 2026 · BMC oral health

BACKGROUND: Pain is the common complication after tooth extraction, while the reasons behind it still remains. Insomnia, another prevalent issue, negatively affects physical, mental health, and quality of life. The relations between…

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Negative / Null Result ReportOpen accessMedicine

Dose and clinical impact of delineation variability in brain metastases treated with stereotactic radiotherapy.

Perrot A, Dissaux B, Roux AC et al. · 2026 · Clinical and translational radiation oncology

Introduction Accurate delineation is critical for stereotactic radiotherapy (SRT) of brain metastases. We evaluated how inter-reader delineation variability affects target dose coverage and local relapse-free survival (LRFS). Methods and…

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