Failed Experiment ReportMedicine
Peirano G, Walker SD, Duong MS et al. · 2026 · European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology
Introduction Metallo-β-lactamase (MBL)-producing Enterobacterales are increasing in frequency and treatment options are limited. Aztreonam/avibactam (AZA) and aztreonam (ATM) plus ceftazidime/avibactam (CZA) showed activities against these…
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Dimitriadis C, Konsta K, Çinar ME et al. · 2025 · Preprint
Abstract Citizen science has become a powerful tool for generating extensive ecological data and fostering public engagement in environmental monitoring and conservation initiatives. In marine environments, where monitoring is challenging…
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Hayashi T, Mizobuchi K, Higa N et al. · 2026 · Ophthalmic genetics
Purpose To assess the detectability of the pathogenic RP1 Alu insertion using the PrismGuide™ inherited retinal dystrophy (IRD) panel, which targets 82 IRD genes, and whole-exome sequencing (WES). Methods A girl diagnosed with early-onset…
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Nichols S, Estandía A, Young CM et al. · 2026 · International journal for parasitology
Parasites are ubiquitous and exert varied ecological and evolutionary pressures on their hosts. Yet, characterising parasite diversity and distributions can be challenging and costly. Leveraging existing data to identify parasites is thus…
View details →Negative / Null Result ReportOpen accessMedicine
He C, Gu X, Liu Y et al. · 2026 · Frontiers in cellular and infection microbiology
Objective This study aims to investigate the impact of mutations within the major hydrophilic region (MHR) of the hepatitis B virus (HBV) S gene on the expression, secretion, and antigenicity of hepatitis B surface antigen (HBsAg), and…
View details →Failed Experiment ReportOpen accessMedicine
Salahat D, Mujahed R, Jaber M et al. · 2026 · Oxford medical case reports
Tuberous Sclerosis Complex (TSC) is a rare genetic disorder characterized by the development of benign tumors in multiple organs. This report presents an unusual case of early-onset renal cystic disease in a 1-year-old male with TSC,…
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Saad F, Shams S, Ayaz S et al. · 2025 · Journal of medical virology
Cytomegalovirus (CMV) poses significant risks to infants and immunocompromised individuals. This study investigated the prevalence, associated risk factors, and phylogenetic profile of CMV DNA in the breast milk of lactating mothers in…
View details →Negative / Null Result ReportOpen accessMedicine
Ueda M, Mitani H, Nakaki Y et al. · 2025 · Interventional radiology (Higashimatsuyama-shi (Japan)
Purpose: To evaluate the performance of automated tumor-feeder detection software in transarterial chemoembolization for hepatocellular carcinoma using angio-computed tomography. Material and Methods: This was a retrospective study of 107…
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Cui N, van Beers RJ, Smeets JBJ et al. · 2025 · Preprint
Emerging evidence suggests that decision making is not a purely cognitive process preceding motor output but rather an embodied phenomenon in which the sensorimotor system actively shapes choice selection. Beta oscillations (13–30 Hz) over…
View details →Negative / Null Result ReportOpen accessMedicine
Mottaghi M, Manda P, Morton EA et al. · 2025 · Cureus
We report the case of a 58-year-old woman who initially presented to the emergency department with intermittent nausea, vomiting, and left upper quadrant abdominal pain for six days. As part of the abdominal pain workup in the emergency…
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Smith BJ, Stafne ET, Read QD · 2025 · PhytoFrontiers™
Phytophthora root rot is a major disease of blueberry that relies on cultural practices, including soil amendments, for disease management. We evaluated the effect of three cover crops on the establishment and growth of southern highbush…
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Akinosho A, Alexander J, Floyd K et al. · 2025 · Preprint
Transgenerational inheritance of learned behaviors remains a controversial topic in biology. The Murphy lab previously demonstrated that C. elegans exposed to pathogenic Pseudomonas aeruginosa (PA14) not only learn to avoid this bacterium…
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Ruiz-Rebollo ML, Muñoz-Moreno MF · 2025 · Medicina clinica
Background Acute pancreatitis can affect elderly people. Conflicting results have been published regarding the role of age in the course of this life-threatening disease. Aim To assess the clinical outcomes of acute pancreatitis in…
View details →Negative / Null Result ReportOpen accessMedicine
Wilmshurst P · 2026 · Clinical medicine (London, England)
One-quarter of adults have a persistent (patent) foramen ovale (PFO). Right-to-left shunting through a PFO can facilitate paradoxical thromboembolism, cryptogenic stroke, paradoxical gas embolism, decompression sickness, arterial…
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Wei Q, Wang SA, Garcia-Manero G et al. · 2025 · Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Identification of cytogenetic abnormalities is critical for the classification and risk stratification of myelodysplastic syndromes (MDS). Optical genome mapping (OGM) is an emerging cytogenomic platform that enables high-resolution…
View details →Negative / Null Result ReportOpen accessMedicine
Noorelahi Y · 2025 · Radiology research and practice
Objective Accurate meniscal tear diagnosis is essential for proper knee injury management. While MRI is the gold standard, ultrasound (US) offers a cost-effective alternative. However, its accuracy compared to arthroscopy remains…
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Robinson ZP, Steele J, Helms ER et al. · 2025 · Preprint
ABSTRACT Purpose There is growing emphasis on investigating heterogeneity in resistance training (RT) outcomes, likely motivated by observations of substantial gross variability in training effects. However, gross variability does not…
View details →Negative / Null Result ReportOpen accessMedicine
Al Sawafi M, Potdar S · 2025 · Trauma case reports
Background Focused Assessment with Sonography for Trauma (FAST) is a cornerstone in the early assessment of trauma patients. However, a negative initial FAST does not always rule out intra-abdominal injury. Case presentation A middle-aged…
View details →Negative / Null Result ReportMedicine
Cooper WR, Ohler B, Wenninger EJ et al. · 2025 · Environmental entomology
Bactericera maculipennis (Crawford) and Bactericera cockerelli (Šulc) (Hemiptera: Triozidae) share hosts within the Solanaceae and Convolvulaceae (Solanales), and both are associated with "Candidatus Liberibacter solanacearum" (Lso). Lso,…
View details →Negative / Null Result ReportMedicine
Xia MH, Liu KC, Zhao W et al. · 2025 · Brachytherapy
Purpose To compare the effectiveness and safety of CT-guided iodine-125 seed brachytherapy in conjunction with chemotherapy against chemotherapy alone for the management of intermediate and advanced non-small cell lung cancer (NSCLC)…
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Joly A, Thoumas J, Lambert A et al. · 2024 · Preprint
Dysregulation of energy metabolism, including hyperglycemia, insulin resistance and fatty liver have been reported in a substantial proportion of lean children. However, non-obese murine models recapitulating these features are lacking to…
View details →Negative / Null Result ReportOpen accessMedicine
Kavoussi PK, Weiss J, Pyo J et al. · 2026 · The Journal of urology
Purpose To assess varicocele repair effect on semen parameters and improved candidacy for in vitro fertilization/intracytoplasmic sperm injection or lesser involved treatment options depending on semen parameter response following…
View details →Negative / Null Result ReportOpen accessMedicine
Strowd RE, de la Fuente M, Bauer TM et al. · 2026 · Neuro-oncology advances
Recurrent isocitrate dehydrogenase (IDH) wild-type glioblastoma has no established standard-of-care treatment. Preclinical models have demonstrated that hypoxia-inducible factor-2 alpha (HIF-2α) contributes to stabilizing the hypoxic…
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Yin H, Yu Y, Shen Y · 2024 · International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience
Cerebellofaciodental syndrome characterized with dysmorphic features, intellectual disability, and brain anomalies. Now its clinical spectrum expanded more manifestations including bilateral sensorineural hearing impairment and inner ear…
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Gerpe C, Toscano MJ · 2024 · Journal of Applied Poultry Research.
The aim of our study was to investigate the effects of two interventions (i.e., two treatments across two independent experiments, each with its own control) that were thought to reduce fractures and stress related responses (e.g., changes…
View details →Negative / Null Result ReportOpen accessMedicine
Kaya G, Yüksel H, Taneli F et al. · 2026 · Clinical and translational science
In cat sensitized children, decision to eliminate exposure to cats depends on the clinical outcome. In this study, we aimed to examine the relationship between molecular cat allergen sensitization and exhaled breath condensate (EBC) IL-4,…
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Khin STMM, Jafar SM, Ju M et al. · 2025 · Journal of virological methods
Feline morbillivirus (FeMV) is a globally emerging virus that has been linked to chronic kidney disease (CKD) in infected cats. Immunological assays, such as enzyme-linked immunosorbent assay (ELISA), are important for studying the virus…
View details →Negative / Null Result ReportOpen accessMedicine
Lagström RMB, Bräuner KB, Frandsen MN et al. · 2026 · Endoscopy international open
Background and study aims Because most colorectal polyps are diminutive and carry minimal cancer risk, artificial intelligence (AI) might enable diagnostic strategies such as leave-in-situ and resect-and-discard, provided it meets…
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Rodgers TW, Mock KE · 2025 · Preprint
Environmental DNA (eDNA) offers a sensitive tool for detecting aquatic species, including those at low population densities. However, effective use of eDNA in conservation and monitoring efforts requires an understanding of detection…
View details →Negative / Null Result ReportMedicine
Javaugue V, Pascal V, Nasr SH et al. · 2025 · Kidney international
Introduction Proliferative glomerulonephritis with monoclonal immunoglobulin deposits (PGNMID) is classified within the spectrum of monoclonal gammopathy of renal significance (MGRS). However, PGNMID features an unexpected low rate of…
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