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Browse the failure-mode index

21,691 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result Report

The Relationship between Obsessive Compulsive Personality and Obsessive Compulsive Disorder Treatment Outcomes: Predictive Utility and Clinically Significant Change

Shalane K. Sadri, Peter M. McEvoy, Sarah J. Egan et al. · 2017 · Behavioural and Cognitive Psychotherapy

Background: The evidence regarding whether co-morbid obsessive compulsive personality disorder (OCPD) is associated with treatment outcomes in obsessive compulsive disorder (OCD) is mixed, with some research indicating that OCPD is…

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Negative / Null Result Report

Did Expanded Dental Insurance Reduce Out-of-Pocket Expenditures on Dental Care among Older Adults in Korea? Interrupted Time-Series Analysis

Nam-Hee Kim, Se-Hwan Jung, Ichiro Kawachi · 2021 · International Journal of Environmental Research and Public Health

The Korean National Health Insurance extended its coverage to reduce the economic burden of receiving dentures and implants for older adults in 2012 and 2014, respectively. We examined whether the new policy resulted in reduced…

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Negative / Null Result Report

13C Labelling of Litter Added to Tea (Camellia sinensis L.) Plantation Soil Reveals a Significant Positive Priming Effect That Leads to Less Soil Organic Carbon Accumulation

Xiangde Yang, Kang Ni, Lifeng Ma et al. · 2022 · Agronomy

Although annual return of litter occurs in tea (Camellia sinensis L.) plantations, the level of soil organic carbon (SOC) therein remains relatively low. The exact impacts of pruned litter on soil and its association with SOC accumulation…

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Negative / Null Result Report

Motor Imaginary Task Classification using Statistically Significant Time Domain and Frequency Domain EEG features

Murside Degirmenci, Yilmaz Kemal Yuce, Yalcin Isler · 2022 · Journal of Intelligent Systems with Applications

Motor Imaginary (MI) electroencephalography (EEG) signals are obtained when a subject imagines a task without essentially applying it. The accurate decoding of MI EEG signals plays an important role in the design of brain-computer…

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Negative / Null Result Report

Comparison of PD-L1 IHC 22C3 PharmDx Combined Positive Score (CPS) in Primary Versus Metastatic Nodal Squamous Cell Carcinomas of the Head and Neck: Is There a Significant Difference?

Ahmet Surucu, Tieying Hou, Matthew Kuhar et al. · 2023 · Applied Immunohistochemistry & Molecular Morphology

PD-L1 IHC 22C3 pharmDx is an FDA-approved companion test to select patients for anti-PD-L1 immunotherapy. In head and neck squamous cell carcinoma PD-L1 expression is determined using a Combined Positive Score (CPS), which evaluates…

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Negative / Null Result Report

No Significant Difference Between Intramedullary and Extramedullary Button Fixation for Distal Biceps Brachii Tendon Rupture After Cyclic Loading in a Cadaver Model

Aditi Majumdar, Christina Salas, William Chavez et al. · 2021 · Arthroscopy, Sports Medicine, and Rehabilitation

Purpose To biomechanically compare intramedullary (IM) versus extramedullary (EM) distal biceps button fixation under cyclic loading conditions, which is most representative of postoperative physiologic status. Methods This controlled…

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Negative / Null Result Report

Floral scent of the Mediterranean fig tree: significant inter-varietal difference but strong conservation of the signal responsible for pollinator attraction

Li Cao, Younes Hmimsa, Salama El fatehi et al. · 2023 · Scientific Reports

Abstract For thousands of years, humans have domesticated different plants by selecting for particular characters, often affecting less-known traits, including the volatile organic compounds (VOCs) emitted by these plants for defense or…

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Negative / Null Result Report

State Anxiety after Exergame Beach Volleyball Did Not Differ between the Single and Multiplayer Modes in Adult Men

Vinnycius de Oliveira, Ricardo Viana, Naiane Morais et al. · 2021 · International Journal of Environmental Research and Public Health

This study compared the exergame beach volleyball’s acute effects on state anxiety level in single vs. multiplayer mode in adult men. Sixty adult men (age: 21.98 [4.58] years, body mass: 75.40 [15.70] kg, height: 1.77 [0.09] m, and body…

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Negative / Null Result Report

Normocalcaemic hyperparathyroidism and primary hyperparathyroidism: least significant change for adjusted serum calcium

Marian Schini, Richard Jacques, Eleanor Oakes et al. · 2021 · European Journal of Endocrinology

Introduction The least significant change (LSC) is a term used in individuals in order to evaluate whether one measurement has changed significantly from the previous one. It is widely used when assessing bone mineral density (BMD) scans.…

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Negative / Null Result Report

Biological variation of thiopurine methyltransferase enzyme activity: when has a significant change taken place?

Remco van Egmond, Murray L Barclay, Paul KL Chin et al. · 2013 · Annals of Clinical Biochemistry: International Journal of Laboratory Medicine

Background Thiopurine methyltransferase (TPMT) enzyme activity is measured before initiating thiopurine therapy to reduce the risk of severe drug-associated myelotoxicity in patients with low enzyme activity. TPMT activity may vary over…

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Negative / Null Result Report

No significant association of repeated messages with changes in health compliance in the COVID-19 pandemic: a registered report on the extended parallel process model

Jingwen Yang, Xue Wu, Kyoshiro Sasaki et al. · 2021 · PeerJ

When people are confronted with health proposals during the coronavirus disease 2019 (COVID-19) pandemic, it has been suggested that fear of COVID-19 can serve protective functions and ensure public health compliance. However, health…

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