12,241 real negative results, null findings, and replication failures in Medicine. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Balakrishnan P, Saravanan S, Vignesh R et al. · 2025 · Indian journal of medical microbiology
Background Hepatitis C virus (HCV) is still a serious public health issue because it can cause cirrhosis, hepatocellular carcinoma (HCC), and chronic hepatitis. In almost 70 % of cases, HCV infection results in chronic persistence, which…
View details →Rezaie MJ, Allahveisie A, Nikkhoo B et al. · 2025 · International journal of fertility & sterility
Background Oocyte in vitro maturation (IVM) is a valuable technology applied to acquire fully developed oocytes for several clinical purposes. Despite substantial research on optimizing culture media, the success rate of IVM remains low.…
View details →Lindqvist J, Askling J, Lampa J · 2023 · RMD open
Objective To assess associations between inflammatory remission, formal treatment targets and the likelihood of starting a new disease-modifying antirheumatic drug (DMARD), among patients with early rheumatoid arthritis (RA). Methods…
View details →Wilkinson T, Booth K · 2025 · The Surgical clinics of North America
The management of perianal Crohn's disease is challenging and complex and requires a multidisciplinary approach as a favorable working relationship between gastroenterologists and colorectal surgeons is necessary to provide excellent care…
View details →Hom B, McIntee D, Zhang YP et al. · 2025 · Saudi journal of anaesthesia
Background Ketamine has been shown to be an effective treatment at sub-anesthetic doses for various chronic pain conditions. This study assesses the relationship between oral ketamine and the incidence of adverse side effects in patients…
View details →Garg A, Strunk A, Midgette B et al. · 2026 · JAMA dermatology
Importance Accurate classification and reliability in assessment for lesions of hidradenitis suppurativa (HS) by investigators is critical to the determination of responder status and to overall data quality in clinical trials. Objective…
View details →Estudillo AJ, Dark O, Wiener JM et al. · 2025 · Brain sciences
Background/Objectives: Previous studies have reported associations between prosopagnosia and spatial navigation, but it remains unclear whether this link is merely coincidental (i.e., observable only in prosopagnosia) or genuinely…
View details →Li H, Hao W, Maeda E et al. · 2025 · Reproductive biomedicine online
Research question Are physical activity and sedentary time associated with the DNA fragmentation index (DFI) score and conventional semen parameters in healthy Japanese men? Design Baseline data from the Preconception Research and…
View details →Evonko CJ, Vigilante KC, Leli NB et al. · 2026 · Journal of substance use and addiction treatment
Introduction Overdose deaths attributed to opioid misuse resulted in over 50,000 deaths in 2024. Opioid agonist therapies such as methadone and buprenorphine are effective for the treatment of opioid use disorder (OUD). Yet, patient…
View details →Wang J, Liu S, Zhang X · 2025 · Advances in medical sciences
Purpose In this study, we examined novel autoantibodies targeting tumor-associated antigens (TAAs) as biomarkers for clinical assessment of hepatocellular carcinoma (HCC) in a Chinese population. Methods and methods A total of 119 patients…
View details →Salari S, Fazeli-Tabar S, Karimi A et al. · 2026 · Scientific reports
Volatile Organic Compounds (VOCs) from nail products pose potential health risks to technicians and clients. The present study investigates the exposure of nail technicians to VOC and assesses the effectiveness of dilution ventilation in…
View details →Li V, McClure H, Patel R et al. · 2025 · Vaccine
Background Vaccination helps prevent infections and associated sequelae, especially in older adults. Since the degree to which vaccine responses are influenced by medications is not well described, we examined the association of medication…
View details →Wachholz F, Gamper N, Kruse S et al. · 2026 · JMIR pediatrics and parenting
Background Physical activity (PA) is essential for the healthy development of children. However, the pervasive presence of digital technologies has made digital gaming (DG) a prominent part of children's everyday lives. As children grow up…
View details →Hassan Elnadif H, Darvell BW · 2024 · Dental materials : official publication of the Academy of Dental Materials
Objective To review the published evidence for the role of cross-head speed on the apparent mechanical properties and bond strength of filled resins to tooth structure in order to identify the causes of inconsistency and contradictory…
View details →Longoni M, Marmiroli A, Falkenbach F et al. · 2026 · International journal of urology : official journal of the Japanese Urological Association
Introduction We assessed the extent of pelvic lymph node dissection (PLND) at partial cystectomy (PC) according to PC eligibility (≤cT2 stage, tumor ≤ 3 cm and segmental resection possible) and tested its effect on cancer-specific…
View details →Alqahtani R, Sulaiman KA, Aljuhani O et al. · 2025 · Heart & lung : the journal of critical care
Background Older adults are at a higher risk of developing venous thromboembolism (VTE), particularly when admitted to the Intensive Care Units (ICUs). Parenteral anticoagulation is the primary method used for thromboprophylaxis in…
View details →Li J, Li A, Jiao J et al. · 2025 · Scientific reports
To evaluate effects of 10-day high-definition transcranial direct current stimulation (HD-tDCS) over the dorsal medial prefrontal cortex (DMPFC) in patients with chronic insomnia. Fifty-five chronic insomnia patients were randomized into…
View details →Squillaro D, Bixter MT · 2025 · Journal of forensic sciences
Individuals who commit criminal behaviors are often thought to prioritize short-term goals rather than long-term goals (i.e., a present vs. a future time orientation). Though previous theories of crime and empirical research support a…
View details →Szameitat AJ, Szameitat DP · 2026 · Psychological research
Contrary to the widespread stereotype that women are better at multitasking than men, no consistent sex differences in multitasking abilities between males and females have been found. We developed a novel multitasking paradigm consisting…
View details →Romoli M, Vitiello M, Lotti EM et al. · 2025 · Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
Background Data on cardioembolic prevention with direct oral anticoagulants (DOAC) in atrial fibrillation (AF) patients with previous gastric surgery are lacking. We report inter- and intra-individual differences in DOAC concentration in…
View details →Konrad M, Shah B, Rady E et al. · 2025 · American journal of surgery
Background Our objective was to assess the association of completeness and level of spinal cord injury (SCI) with the need for tracheostomy and identify additional risk factors predictive of tracheostomy. Methods This was a retrospective…
View details →Grieco T, Moliterni E, Paolino G et al. · 2024 · Dermatology practical & conceptual
Introduction Few studies have explored the intricate connections between vitamin D receptor (VDR) gene polymorphisms, VDR, tight junction (TJ) protein expression and clinical features of atopic dermatitis (AD). Methods From 43 adult AD…
View details →Sikoki B, Larastiti C, Suriastini NW et al. · 2024 · International journal of adolescent medicine and health
Introduction Sexual and reproductive health (SRH) education in Yogyakarta, Indonesia, is contentious due to societal and religious taboos in the Javanese Muslim community and being misunderstood as a potential catalyst for the premarital…
View details →Verrewaere D, Reyniers P, Vandevivere H et al. · 2024 · Hand surgery & rehabilitation
Background Carpal tunnel release can be performed as open or endoscopic surgery. In WALANT (wide awake local anesthesia no tourniquet) a tourniquet is not used, ensuring less discomfort for the patient. In locoregional distal nerve block,…
View details →Huang Y, Zheng J, Yang Z et al. · 2026 · Frontiers in medicine
Introduction While vonoprazan-amoxicillin dual therapy has achieved > 90% eradication rates for Helicobacter pylori (H. pylori) in clinical trials, its effectiveness in "real-world" regions with high primary antibiotic resistance and…
View details →Chestnutt IG, Pattinson R, Brocklehurst P et al. · 2026 · British dental journal
Background Problems relating to the commissioning and delivery of National Health Service (NHS) General Dental Services (GDS) have been well-documented.Objectives This study aimed to gain consensus on issues deemed of importance to the…
View details →Smith AA, Jeon D, Rudy K et al. · 2025 · Scientific reports
To characterize the potential long-term impact of intrauterine growth restriction (IUGR), we assessed the endocrine and hematological consequences of IUGR at birth and in the early postnatal period. Piglets (n = 911) were collected…
View details →Steffens NA, Petreceli RR, Azevedo VC et al. · 2025 · Clinical biochemistry
Introduction Healthcare systems face several challenges, with microbial infections being one of the main concerns. Therapeutic drug monitoring (TDM) is a strategy that has been encouraged to optimize antimicrobial regimens, particularly…
View details →Salmanov AG, Bondar TP, Lykhota KM et al. · 2025 · Wiadomosci lekarskie (Warsaw, Poland : 1960)
Objective Aim: The aim of this study was to evaluate the microbial contamination of dental unit waterlines (DUWLs) and characterize the microbial communities of biofilms in dental chair units (DCUs) from different specialties in Ukrainian…
View details →Yamasoba T, Uranaka T, Koyama H et al. · 2025 · Journal of clinical medicine
Background/Objectives : Since we started endoscopic stapes surgery, we have frequently noticed a white spot (WS) with a clear boundary on the bone surface around the fissula ante fenestrum (FAF) in otosclerosis cases. We investigated the…
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