12,263 real negative results, null findings, and replication failures in Medicine. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Anwar, Alshammakh, Alharb et al. · 2026 · Medical ultrasonography
The left atrioventricular coupling index (LACI) reflects the close interaction between left atrial (LA) and left ventricular (LV) dynamics. The study aimed to verify the diagnostic value of LACI in defining the cardiac…
View details →Madabhushi, Patel, Tse-Kang et al. · 2026 · PloS one
There is a concerning trend of misinformation of healthcare related content on social media. Recent studies have examined themes and narratives about Crohn's disease but have not quantitatively assessed the accuracy and quality of content…
View details →Chen, Li, He et al. · 2026 · High altitude medicine & biology
Chen, Biao, Shuai Li, Kun He, Dunzhu Basang, Yuzhen Suolang, Fang Li, Jiangcun Silang, Hongyuan Yi, Langjie Jinmei, La Dan, Deqing Ciren, Haifeng Xu, and Dong Wu. Mitigating Intraoperative Fatigue in Surgeons at High Altitude: A…
View details →Araújo, Taveira, Godoy et al. · 2026 · CoDAS
Investigate the effectiveness of a therapeutic program with chin tuck against resistance (CTAR) exercises, compared to the chin-down (CD) maneuver, on signs suggestive of dysphagia, maximum isometric tongue pressure, and therapeutic…
View details →Kurnaz, Kaygisiz, Akay et al. · 2026 · Brazilian oral research
This study aimed use cone beam computed tomography (CBCT) to compare the maxillary sinus volume and transverse dimensions between sides with and without palatally impacted maxillary canines. The CBCT records of 47 patients with unilateral…
View details →Du-Shieng Chien, R. Sandri, D. Tang-Liu · 1992 · Drug Metabolism And Disposition
Etretinate, a highly lipophilic retinoid, is known to accumulate in the human body with a slow systemic elimination (half-life approximately 100 days) after long-term treatment. Retinoids with high lipophilicity and slow body elimination…
View details →Xie X, Wang S, Qin X et al. · 2026 · Medicine
The optimal timing of lacrimal duct probing for congenital nasolacrimal duct obstruction (CNLDO) remains debated. This study aimed to evaluate the association between age at probing and short term treatment outcomes in infants with CNLDO.…
View details →Du X, Zhao D, Yuan J et al. · 2026 · Poultry science
Heat stress (HS) poses a significant threat to poultry production by impairing the growth and health of broilers. Luteolin (Lut) is a natural flavonoid with potent antioxidant properties. In vitro, Lut mitigated HS-induced oxidative injury…
View details →Tavares KIMC, Santos-Junior AO, Pinto JC et al. · 2026 · Brazilian oral research
The aim of this study was to evaluate the effect of immersion in an acidic (butyric acid - BA; pH 4.1) or neutral (phosphate-buffered saline - PBS; pH 7.0) environment on the physical behavior of Bio-C Sealer (BCS) or AH Plus Jet (AHPJ)…
View details →Akitomo T, Kaneki A, Nishimura T et al. · 2026 · International dental journal
Although many studies have examined large language models (LLMs) for dental diagnosis, most focus on a single topic, and few have investigated their broader usefulness for the variety of patients. Twenty-five cases meeting the eligibility…
View details →Zeynali N, Akbari M, Ghezelbash S · 2026 · Journal of education and health promotion
Background Since chronic heart failure would cause various physical outcomes and limitations, it could create significant changes in the mental status of the patients. One of the problems among these patients is increased stress levels.…
View details →Akarakian R, Geamanu A, Moffat A et al. · 2026 · BMC musculoskeletal disorders
BACKGROUND: Jumper’s knee or patellar tendinosis is a debilitating condition occurring in up to 40% of athletes that perform jumping, rapid acceleration and deceleration movements. Minimally invasive percutaneous ultrasonic tenotomy…
View details →Eşkil KG, Eşkil R, Yapıcı A · 2026 · BMC sports science, medicine & rehabilitation
Background The present study aims to examine the impact of badminton training programs on the attention and motor skills performance of students with specific learning disabilities (SLDs). Methods The study was carried out with students at…
View details →Shin C, Riehl JT · 2026 · The journal of knee surgery
Abstract As the population continues to grow and age, the number of projected total knee arthroplasty (TKA) procedures is expected to grow substantially by 2030. This retrospective study reviews peripheral vascular disease (PVD) and…
View details →Saleh RS, Elbattawy EA, Hamza S et al. · 2026 · Scientific reports
The aim of this study was to compare the effect of Calcium Aluminate- Calcium Silicate based experimental pulp capping material with the commercially available Mineral Trioxide Aggregate (MTA) in terms of dentin bridge formation and pulp…
View details →Kataruka M, Sk J, Bhattacharjee S et al. · 2026 · Cureus
Background Orthotic intervention is a non-invasive and commonly used treatment for trigger finger (TF). Among the various splinting options, the comparative effectiveness of proximal interphalangeal joint block orthosis (PIPJ-BO) and…
View details →Aziz NN, Hassan RM, Ibrahim RA et al. · 2026 · Clinical medicine insights. Arthritis and musculoskeletal disorders
Background Late-onset rheumatoid arthritis (LORA) poses a great challenge for physicians regarding diagnosis and treatment. The prognosis for LORA was better in some early research but worse in more recent trials. Objectives The study aim…
View details →Liu B, Li J, Dai S et al. · 2026 · The Journal of craniofacial surgery
To investigate the difference between the 3-dimensional structure of the cavity in patients with isolated cleft palate and Pierre-Robin syndrome with cleft palate. Retrospective measurements of high need ratio (NR), velopharyngeal gap…
View details →Guo L, Wang J, Du D · 2026 · Frontiers in oncology
Purpose To investigate the efficacy and safety of deep hyperthermia combined with tislelizumab and chemotherapy in patients with advanced squamous non-small cell lung cancer (NSCLC). Methods A total of 100 patients with advanced squamous…
View details →Domingo PT, Berger GK, Gray P et al. · 2026 · The Journal of the American Academy of Orthopaedic Surgeons
Purpose We evaluated the safety outcomes of opioids alone versus opioids plus low-dose gabapentinoids in patients naïve to both opioids and gabapentinoids, after total joint arthroplasty (TJA) of the knee, hip, or shoulder. Methods This…
View details →Lin Z, Chen Y, Zang H et al. · 2026 · Operative neurosurgery (Hagerstown, Md.)
Background and objectives Bone and soft tissue tumors are significant causes of limb amputation. Regenerative peripheral nerve interface (RPNI) is an effective method for preventing neuroma formation in residual nerves. However, the…
View details →Monteiro L, Lima J, Silva L et al. · 2026 · Journal of clinical medicine
Background: Artificial intelligence (AI) is expected to play an increasingly important role in medicine and dentistry. While its diagnostic potential has been tested in various medical fields, limited research exists on its applications…
View details →Yoshikawa M, Yoshikawa Y, Uemura M et al. · 2026 · Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine
This study investigated whether neuromuscular electrical stimulation (NMES) applied to the gluteus maximus alone or in combination with the hamstrings redistributes interface pressure in the sacral and ischial regions during 60°…
View details →Abdullah NA, Hassan RK, Muhammed AK et al. · 2026 · Medicine
Ectopic pregnancy (EP) remains a major cause of early pregnancy-related morbidity and mortality. It can significantly impact future fertility and is associated with various risk factors. To investigate the incidence, clinical profile, and…
View details →Adawy SNE, Aboulftouh DM, AbuAmu ST et al. · 2026 · The Saudi dental journal
To evaluate the stain resistance of repressed IPS Emax and Celtra Press after thermo-mechanical fatigue. Two pressable glass ceramics, IPS e.max press (Ivoclar, Vivadent) and Celtra press (Dentsply, Sirona), were used in this study. Thirty…
View details →Almadani O, Alfakhri A, Asiri I et al. · 2026 · Pharmacoepidemiology and drug safety
Objective Incidents of infections associated with biosimilar biological disease-modifying antirheumatic drugs (bDMARDs) have been communicated to the Saudi Food and Drug Authority (SFDA). This study aimed to evaluate the infection risk…
View details →Özfevzi R, Taner RL · 2026 · BMC oral health
Background Orthodontic malocclusion may affect both functional and psychosocial aspects of health; however, its relationship with global self-esteem in young adults remains unclear. This study aimed to compare self-esteem levels according…
View details →Truong D, Nguyen KC, Chansangpetch S et al. · 2026 · Clinical ophthalmology (Auckland, N.Z.)
Purpose To compare the intraocular pressure (IOP)-lowering efficacy and safety of netarsudil, a Rho-associated kinase (ROCK) inhibitor, among eyes with open-angle glaucoma (OAG), combined-mechanism glaucoma (CMG), and angle-closure…
View details →Wang R, Ren Y, Song Y et al. · 2026 · Journal of cardiothoracic surgery
Objective Comparison of the efficacy of the oXiris filter and the ST-100 filter in patients with postoperative cardiac surgery infections combined with acute kidney injury. Methods This is a retrospective cohort study of patients with…
View details →Siddappa PK, Barakat MT, Zhou MJ et al. · 2026 · Surgical endoscopy
Background and aims Duodenoscopes with disposable distal end caps (DDEC) have been introduced to reduce the risk of transmitting multi-drug-resistant organisms compared to conventional reusable duodenoscopes (CRD). However, there have been…
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