Negative / Null Result ReportMedicine
Sternberg, Podolsky, Yu et al. · 2026 · The journal of prevention of Alzheimer's disease
High cholesterol contributes to the development and progression of dementia due to both Alzheimer's disease (A.D.) and vascular pathology. However, the effects of lipid-lowering regimen (LLR) on cognitive dysfunction and brain…
View details →Negative / Null Result ReportMedicine
Lau, Fok, Lee et al. · 2026 · PloS one
Ankle joint quasi-stiffness is a measure representing the control of quiet standing. Here we investigated three methods for determining parameters associated with ankle joint quasi-stiffness. Eleven healthy, young males were asked to stand…
View details →Negative / Null Result ReportMedicine
Kizuki, Kaneko, Taniguchi et al. · 2026 · Sleep and biological rhythms
We previously found that seasonal changes in sleep duration were affected by sex, residential area, and age in Japanese community residents. This study aimed to determine whether these factors also affect the seasonality of…
View details →Negative / Null Result ReportMedicine
Yang, Jang, Park et al. · 2026 · Veterinary ophthalmology
To evaluate the clinical efficacy of a newly developed adhesive tissue sealant, gelatinized cornea-derived decellularized extracellular matrix (Cod-ECM) for the treatment of stromal ulcers in dogs. This study included 60 eyes of 56 dogs…
View details →Negative / Null Result ReportMedicine
Campbell, Wilson, Du Plessis et al. · 2026 · Journal of neurotrauma
Following a mild traumatic brain injury (mTBI), up to 30% of individuals will experience persisting symptoms beyond 3 months. Repetitive transcranial magnetic stimulation (rTMS) is a noninvasive neuromodulation technique that has shown…
View details →Negative / Null Result ReportMedicine
Antoniou, Yang, Juurlink et al. · 2026 · Clinical pharmacology and therapeutics
Fentanyl, hydromorphone, and oxycodone are metabolized by cytochrome P450 3A4 (CYP3A4). Co-administration with CYP3A4-inhibiting macrolides (clarithromycin or erythromycin) may increase opioid concentrations and overdose risk, but the…
View details →Negative / Null Result ReportMedicine
Huggins, Martinez, Baird et al. · 2026 · Journal of neurotrauma
Mild traumatic brain injury (mTBI), a common health burden among combat veterans, has been associated with alterations in brain structure. Moreover, post-traumatic stress disorder (PTSD), frequently comorbid with mTBI, is linked to smaller…
View details →Negative / Null Result ReportMedicine
Abdolahi, Li, Zou et al. · 2026 · Translational vision science & technology
To assess the performance of an artificial intelligence deep learning (DL) model compared with neuro-ophthalmologists for the classification of subjects with elevated intracranial pressure (ICP) and papilledema versus control subjects,…
View details →Negative / Null Result ReportMedicine
Gozen, Sezgin, Yavuzer et al. · 2026 · Frontiers in pharmacology
Propofol is a short-acting intravenous hypnotic anesthetic widely used for sedation and the induction and maintenance of general anesthesia. Although it reliably produces unconsciousness, its intrinsic analgesic efficacy remains a subject…
View details →Negative / Null Result ReportMedicine
Schmeisk-Rosa, Andersen, Cordeiro et al. · 2026 · Plant and soil
In highly weathered soils of central Amazonia, where nutrients such as phosphorus (P) and base cations are scarce, fertilization experiments have demonstrated above- and belowground effects on total net primary productivity (NPP). This…
View details →Negative / Null Result ReportMedicine
Yigitbay, Kural, Tanrıverdi et al. · 2026 · Foot & ankle specialist
ObjectiveThis study aimed to identify the possible risk factors for the development of partial bridging and synostosis in the distal tibiofibular joint following surgically treated ankle fracture-dislocations and to examine the effects of…
View details →Negative / Null Result ReportMedicine
Bacchetta, Vacchelli, Pica et al. · 2026 · Ecotoxicology (London, England)
Micro- and nanoplastic toxicity is a growing environmental concern, especially in aquatic ecosystems. This study investigates the acute and chronic effects of polypropylene microfibers (PP MFs), derived from artificially aged surgical face…
View details →Negative / Null Result ReportMedicine
Zhang, Li, Liao et al. · 2026 · International journal of ophthalmology
To evaluate the effectiveness and safety of superselective ophthalmic artery thrombolysis (SOAT) for central retinal artery occlusion (CRAO) beyond 24h after onset. This was a retrospective cohort study of CRAO patients treated from…
View details →Negative / Null Result ReportMedicine
Handayani, Mahata · 2025 · Journal of advanced veterinary and animal research
This study was conducted to investigate the influence of varying levels of oil-enriched tomato powder (OTP) and simvastatin supplementation on the performance and egg quality of laying hens. Two hundred 32-week-old Lohmann-Brown hens were…
View details →Negative / Null Result ReportMedicine
Han, Wang, Shang et al. · 2026 · Journal of hazardous materials
Cadmium (Cd) accumulation in river floodplains is threatening grain safety and agro-ecosystem sustainability. We conducted a 10-month field-mesocosm experiment to evaluate the effectiveness, side effects and underlying mechanisms of three…
View details →Negative / Null Result ReportMedicine
Zhao, Xie, Yu et al. · 2026 · BMC cancer
BACKGROUND: Vessels that encapsulate tumor clusters (VETC) is a powerful predictor of aggressive hepatocellular carcinoma (HCC) and associated with poor outcomes of HCC. Imaging surrogates of VETC potentially help predict postsurgical…
View details →Negative / Null Result ReportMedicine
Li, Tong, Xue et al. · 2026 · Journal of hepatology
Hepatic stellate cells (HSCs) are activated during cholestasis. However, beyond liver fibrosis, whether HSCs influence bile acid (BA) synthesis and homeostasis remain largely unknown. This study investigates the role of activated HSCs…
View details →Negative / Null Result ReportMedicine
Li, Zhou, Xu et al. · 2026 · Microorganisms
The present study investigates the effects of tannic acid (TA) on body composition, immune function, and gut microbiota in Brandt's voles ( Lasiopodomys brandtii ); analyzes the gut microbiota-immune parameter associations during their…
View details →Negative / Null Result ReportMedicine
Almuraikhi, Alkhamees, Tareen et al. · 2026 · Current issues in molecular biology
Glycogen synthase kinase-3 (GSK3) inhibition is a commonly used approach to promote osteogenic differentiation through activation of Wnt signaling. However, 6-bromoindirubin-3'-oxime (BIO), which is commonly used for GSK3 inhibition, also…
View details →Negative / Null Result ReportMedicine
Yıldırım Ş, İnci A, Karaduru Avcı A et al. · 2026 · Biomolecules & biomedicine
Primary membranous nephropathy (pMN) is a principal cause of nephrotic syndrome in adults. The identification of the M-type phospholipase A2 receptor (PLA2R) antigen has significantly advanced non-invasive management; however, the precise…
View details →Negative / Null Result ReportMedicine
Aba O, Yalçın Sezen G, Ersoy Karka O · 2026 · BMC anesthesiology
Purpose This study aimed to evaluate perioperative changes in optic nerve sheath diameter (ONSD) and regional cerebral oxygen saturation (rSO₂) using noninvasive monitoring techniques during laparoscopic abdominal surgery, and to assess…
View details →Negative / Null Result ReportMedicine
Çetinkaya F, Uslu E · 2026 · Journal of perioperative practice
Objective This study aimed to determine whether there is a relationship between patients' health literacy levels and their preoperative anxiety during the preoperative period. Design An analytical cross-sectional study. Methods The…
View details →Negative / Null Result ReportOpen accessMedicine
Sugiarta AP, Anggani HS, Purbiati M · 2025 · Journal of orthodontic science
Objective This study aims to demonstrate the correlation between anterior tooth retraction and changes in the dimensions of the pharyngeal airway in cases of bimaxillary protrusion. Materials and methods Changes in dental parameters and…
View details →Negative / Null Result ReportMedicine
Melnikova, Nechipurenko, Mangin et al. · 2026 · Thrombosis and haemostasis
Subendothelial matrix exhibits a distinctive organization, with collagen fibers beneath the endothelium oriented parallel to the flow and comprising mainly types III and I collagen in arteries and arterioles. However, the significance of…
View details →Negative / Null Result ReportMedicine
Ankmnal Veeranna, Chapman · 2026 · American journal of audiology
The purpose of the present study was to determine whether standard and high-frequency transducers influence test scores on clinically used speech-in-noise (SIN) assessments, such as the Word-In-Noise (WIN) and QuickSIN tests. Sixteen…
View details →Negative / Null Result ReportMedicine
Wu, Zhang, Wang et al. · 2026 · Frontiers in ophthalmology
To assess central corneal thickness (CCT), as well as the density and morphology of corneal endothelial cells (ECD) in myopic eyes. A total of 400 patients scheduled for myopic refractive surgery were consecutively enrolled in this study.…
View details →Negative / Null Result ReportMedicine
Mukhopadhyay, Modgekar, Yang-Hood et al. · 2026 · Scientific reports
Quantal synaptic transmission in vestibular endorgans is glutamatergic. Here, we investigated the vestibular phenotype of deaf Vglut3 -/- (Slc17a8 -/- ) mice from the cellular to behavioral levels. In Vglut3 -/- mice, quantal synaptic…
View details →Negative / Null Result ReportMedicine
Li, Peng, Song et al. · 2026 · Poultry science
The development and utilization of unconventional feed such as sprayed corn bran (SCB) have effectively alleviated the shortage of feed raw materials, although its application in meat geese production has rarely been reported. Therefore,…
View details →Negative / Null Result ReportMedicine
Dambro, Anderson, Clebak et al. · 2025 · Family medicine
The integration of artificial intelligence (AI) in medical education primarily has focused on clinical applications, with limited investigation into its role in learner assessment. This study explores AI usage among family medicine…
View details →Negative / Null Result ReportMedicine
Gayraud, Lequy, Hucteau et al. · 2026 · Ophthalmology science
Age-related macular degeneration (AMD) and cataracts are part of the leading causes of blindness globally, with oxidative stress being a key factor in their development. Air pollution, known to exacerbate oxidative stress, may contribute…
View details →