Vilobelimab to improve clinical outcomes in moderate-to-severe hidradenitis suppurativa through an adjunctive effect on draining tunnels: results of the SHINE double-blind placebo-controlled randomized trial.
Giamarellos-Bourboulis EJ; Jemec GBE; Prens EP; Riedemann NC; Otto I; Weisman J; Pulka G; Nowicki RJ · 2026 · The British journal of dermatology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Background The results of a previous phase IIa trial suggested efficacy of the anti-C5a compound vilobelimab in a small number of patients with severe hidradenitis suppurativa (HS) refractory to adalimumab treatment. Objectives To study…
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Metadata source: Europe PMC · DOI 10.1093/bjd/ljaf398