Negative / Null Result ReportMedicine
Di Girolamo A, Cristallo M, Daddato MF et al. · 2026 · Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society
Chronic rhinosinusitis with nasal polyps (CRSwNP) manifests as either a solitary upper airway involvement or as part of a more intricate clinical picture, such as Cystic Fibrosis (CF). The altered viscoelastic properties of mucus…
View details →Negative / Null Result ReportMedicine
Piper FI, Paula S, Urrutia-Jalabert R · 2026 · Annals of botany
Background and aims Long-term droughts reduce the carbon (C) and water pools of trees, causing mortality. However, the underlying physiological mechanisms explaining tree mortality remain unclear, and evidence from mature forests is…
View details →Negative / Null Result ReportMedicine
Metz AK, Loughmiller SK, Braathen DL et al. · 2026 · The Journal of arthroplasty
Background The use of alternative alignment strategies has become commonplace in performing total knee arthroplasty (TKA). A primary reported benefit of these techniques is a reduction in the need for soft-tissue releases for appropriate…
View details →Negative / Null Result ReportMedicine
Froon-Torenstra D, Renting L, Ijpma I et al. · 2026 · Clinical nutrition ESPEN
Background and aims Malnutrition is common among children with cancer and is related to treatment-related toxicity, mortality and lower quality of life. So far, it remains unknown whether changes in resting energy expenditure (REE)…
View details →Negative / Null Result ReportOpen accessMedicine
Huffman J, Chapple AG, Armbruster P et al. · 2026 · European oral research
Purpose This study sought to compare mechanical properties of beta titanium orthodontic wires to stainless steel and NiTi archwires under different pH conditions and for different time intervals. Materials and methods Twenty samples of 5…
View details →Negative / Null Result ReportMedicine
Saber S, Rifat MMI, Rahimi F et al. · 2026 · Genetics
The rate, molecular spectrum, and fitness effects of mutations vary at all levels of the biological hierarchy, from within individual genomes to among taxonomic domains. Understanding the evolutionary factors underpinning that variation is…
View details →Negative / Null Result ReportOpen accessMedicine
Pizarro DM, Crooks A, Wattiaux MA et al. · 2026 · Translational animal science
Kernza intermediate wheatgrass ( Thinopyrum intermedium [Host] Barkworth & D.R. Dewey) is a novel dual-use perennial grain and forage crop with environmental and economic benefits for farmers. Perennial crop byproducts, such as Kernza…
View details →Negative / Null Result ReportMedicine
Zanesco AP, Spivey DJ, Horn LF et al. · 2026 · Attention, perception & psychophysics
Sustaining the focus of our attention is effortful and cannot be maintained indefinitely. Our minds naturally wander, necessitating effortful control of attention to maintain focus and resist distraction from external events or internally…
View details →Negative / Null Result ReportMedicine
Nazar PHO, Reis FCC, Barbosa HE et al. · 2026 · Journal of inorganic biochemistry
Complexes of the μ-oxo-bis(μ-acetate)diruthenium class exhibit ligand lability at the positions trans to the μ-oxo bridge. Lability is an important property for numerous drugs, such as cis-[Pt(NH 3 ) 2 Cl 2 ], given that its biological…
View details →Negative / Null Result ReportMedicine
Gomez NG, Gomez MA, MacWilliams BA et al. · 2026 · Journal of applied biomechanics
Minimum toe clearance (MTC) location relative to the stance-phase foot, as well as how this location changes with walking speed, helps in better understanding the circumstances when MTC is most relevant. This study helps define where MTC…
View details →Failed Experiment ReportMedicine
Barbaro K, Candida E, Biavati FS et al. · 2026 · Orthodontics & craniofacial research
Objective Traditional biocompatibility assessments primarily address cytotoxicity and bulk material properties but often overlook molecular responses that occur below toxicity thresholds. Detecting these subtle effects is crucial for…
View details →Negative / Null Result ReportMedicine
Incontri D, Kellner CP, Polymeris A et al. · 2026 · Journal of neurointerventional surgery
Background The results of the Early Minimally Invasive Removal of Intracerebral Hemorrhage (ENRICH) trial have renewed interest in minimally invasive hematoma evacuation (MIE) as a treatment option for intracerebral hemorrhage (ICH).…
View details →Negative / Null Result ReportMedicine
Mai K, Salim SR, Tilstra-Ferrell E et al. · 2026 · Journal of forensic nursing
Aims To examine data from an early intervention program for mental health following recent sexual assault (SA) to compare referral and service utilization rates before and after a community-based outreach model was implemented. Methods In…
View details →Replication FailureMedicine
Mesquita JAC, Diniz ACS, Araujo MR et al. · 2026 · International journal of dental hygiene
Dental materials with the potential for caries progression prevention have been an attractive alternative to minimally invasive treatments. Objectives This randomized controlled split-mouth clinical trial aimed to assess, after 18 months,…
View details →Replication FailureMedicine
Rajendran R, Singhania S, Suthar A et al. · 2026 · Reproduction (Cambridge, England)
In brief: An excess of extracellular High-Mobility Group Box 1 protein, an alarmin, in the uterine cavity alters the proportion and phenotype of uterine immune cells. These derangements impair decidualization and adversely impact the…
View details →Negative / Null Result ReportMedicine
Schumacher KR, Dillman J, Goldberg DJ et al. · 2026 · Pediatric cardiology
Fontan-associated liver disease (FALD) is a fibrotic liver disease in individuals with Fontan physiology. This study sought to determine the efficacy of treatment with udenafil, a phosphodiesterase type 5 inhibitor, for reducing liver…
View details →Negative / Null Result ReportMedicine
Tsutsumi T, Kashiwagi H, Imai S et al. · 2026 · Drug research
Background Nausea and vomiting are commonly reported side effects of long-term linezolid therapy, which is indispensable for tuberculosis and osteoarticular infections. Since the mechanism underlying the development of nausea and vomiting…
View details →Negative / Null Result ReportMedicine
Karabacak DD, Doğruya S, Altınışık M et al. · 2026 · Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie
PURPOSE: This study aimed to evaluate the impact of panretinal photocoagulation (PRP) on macular and optic nerve head microvascular parameters using optical coherence tomography angiography (OCTA) in eyes with proliferative diabetic…
View details →Negative / Null Result ReportMedicine
Renner A, Estanich EB, Lynch EA et al. · 2026 · Journal of Applied Poultry Research.
Thermal processes during steam conditioning and pellet die extrusion aid in pelleting but may degrade exogenous feed enzymes. This study determined how ambient temperature interacts with varying steam conditioning temperatures to influence…
View details →Negative / Null Result ReportMedicine
McQueen K, Sivle LD, Khodabandeloo B et al. · 2025 · Marine environmental research
Sparkers are seismic sources commonly used to survey the seabed in areas planned for offshore wind farms. The almost continuous sounds produced by sparkers, with most energy in the frequency range 50Hz - 4 kHz, are audible to both fish and…
View details →Negative / Null Result ReportMedicine
Béllo Carvalho R, Frangos C, Sonawane C et al. · 2026 · Journal of mammalogy
Animals in urban preserves experience both the security of protected habitats and the persistent anthropogenic disturbances of surrounding human-dominated landscapes. During the COVID-19 pandemic, lockdowns temporarily reduced human…
View details →Negative / Null Result ReportMedicine
Halleran M, Balsom AA, Gordon JL · 2026 · Journal of integrative and complementary medicine
Objectives Women experiencing infertility report heightened levels of anxiety, depression, and distress. However, access to affordable mental health care is limited in most areas of the world. Self-directed interventions, including…
View details →Negative / Null Result ReportOpen accessMedicine
Kuroda K, Miyoshi H, Hamamoto K et al. · 2026 · The journal of obstetrics and gynaecology research
Aim More than half of patients with pelvic organ prolapse (POP) complain of lower urinary tract symptoms (LUTS), especially voiding difficulty. Surgical approaches such as laparoscopic sacrocolpopexy (LSC) and transvaginal mesh surgery…
View details →Negative / Null Result ReportMedicine
Roosimaa M, Ilumets H, Kaha T et al. · 2026 · Journal of wound care
Objective The objective of this trial was to compare the clinical performance and safety of a novel wound dressing containing silver and copper nanoparticles (Nanordica; Nanordica Medical OÜ, Estonia) (Ag/Cu) with the ionic silver-based…
View details →Negative / Null Result ReportMedicine
Agarwal R · 2026 · American journal of hypertension
Background The mechanism of hypertension associated with erythropoiesis-stimulating agents in chronic kidney disease (CKD) is complex and remains poorly understood. Methods Here, anemic hypertensive patients with CKD and well-controlled or…
View details →Negative / Null Result ReportMedicine
Tamburro MK, Carlson JA, Yen WK et al. · 2026 · Matrix biology : journal of the International Society for Matrix Biology
Tendon injuries account for considerable and escalating clinical burden. After injury, tendons heal poorly with persistent fibrovascular scar. Unlike healthy tendon which is type I collagen (COL1)-rich and highly-aligned, fibrovascular…
View details →Negative / Null Result ReportMedicine
Lisco A, Borgognone A, Vanpouille C et al. · 2026 · The Journal of infectious diseases
Background The cervicovaginal microbiome may affect HIV-1 susceptibility and can in turn influence the prevalence and clinical course of HIV-1 and other sexually transmitted diseases. As the determinants, immunological correlates and…
View details →Negative / Null Result ReportMedicine
Yin TK, Sengar N, Fang TY et al. · 2026 · European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
PURPOSE: Fluctuating hearing loss in Ménière’s disease (MD) presents a key clinical challenge due to lack of reliable prognostic markers. The clinical value of transient-evoked otoacoustic emissions (TEOAEs) low-frequency components…
View details →Negative / Null Result ReportMedicine
Gkirgkiris K, Charalampaki E, Margioula E et al. · 2026 · Anaesthesia, critical care & pain medicine
Background stive heart failure may coexist and aggravate the non-cardiogenic pulmonary edema of acute respiratory distress syndrome (ARDS). Yet, patients with congestive heart failure are likely under-represented in ARDS trials. We aimed…
View details →Negative / Null Result ReportMedicine
Holian JA, Bolton MD, Wilson DI · 2025 · Current Research in Food Science
Addition of small amounts of glycerol to milk chocolate during the tempering stage can yield a product which exhibits enhanced mechanical strength and retards motion of the continuous phase (cocoa butter, a mixture of fats) of this dense…
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