12,379 real negative results, null findings, and replication failures in Medicine. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
De Luca A, Verschoor S, Hommel B · 2022 · Experimental psychology
Mood has been argued to impact the breadth of human attention, but the empirical evidence supporting this claim remains shaky. Gable and Harmon-Jones (2008) have attributed previous empirical inconsistencies regarding the effect of mood on…
View details →Chapman HA · 2021 · Emotion (Washington, D.C.)
Emotional stimuli modulate cognitive processes such as attention and memory to facilitate an adaptive response to the environment. For example, previous research suggests that fearful facial expressions broaden attention to help the…
View details →Kott A, Brannan S, Wang X et al. · 2023 · Schizophrenia bulletin open
Objectives We sought to evaluate the impact of baseline anxiety levels on drug placebo separation and drug and placebo response in acutely psychotic schizophrenic subjects. Methods In this post-hoc analysis, modified intent-to-treat…
View details →Suhre K, Chen Q, Halama A et al. · 2025 · Nature genetics
Most studies to date of protein quantitative trait loci (pQTLs) have relied on affinity proteomics platforms, which provide only limited information about the targeted protein isoforms and may be affected by genetic variation in their…
View details →Jhelum H, Schäfer R, Kaufer BB et al. · 2025 · Viruses
Porcine cytomegalovirus, more accurately classified as porcine roseolovirus (PCMV/PRV), was shown to be pathogenic in the context of xenotransplantation. Transmission of PCMV/PRV to non-human primates receiving hearts or kidneys from…
View details →Abuleil D, Gorbet D, McCulloch DL et al. · 2025 · Frontiers in neuroscience
Introduction Anodal direct current stimulation (a-tDCS) of the visual cortex is a potential rehabilitation tool for vision disorders such as amblyopia and macular degeneration. However, the underlying neural mechanisms are currently…
View details →Almajed N, Al-Musharaf S, Aldhwayan MM et al. · 2025 · International journal of general medicine
Purpose Certain trace minerals, such as zinc (Zn) and magnesium (Mg), may play a role in glucose regulation and insulin signaling pathways. However, population data from the Middle East are scarce and may differ in terms of dietary and…
View details →Herzig L, Stöckert J, Lochmann M et al. · 2026 · Frontiers in sports and active living
The aim of this study was to determine if positional Worst-Case-Scenarios (WCS) during official games (OG) are replicated in Large-Sided Games (LSG) with a similar Area per Player (ApP) as OG. Twenty-one football players from the second…
View details →Hoffman LJ, Foley JM, Tanrıverdi B et al. · 2025 · Memory & cognition
Memories are pliable and can be biased by post-encoding information. In targeted memory reactivation (TMR) studies, participants encode information then sleep, during which time sounds or scents that were previously associated with the…
View details →Bugden S, Szkudlarek E, Brannon EM · 2021 · Trends in neuroscience and education
Background Prior studies reported that practice playing an approximate arithmetic game improved symbolic math performance relative to active control groups in adults and preschool children (e.g. Park & Brannon, 2013, 2014; Park et al.,…
View details →Schriefl C, Schoergenhofer C, Buchtele N et al. · 2022 · Journal of personalized medicine
Background The clinical value of a prognostic score depends on its out-of-sample validity because inaccurate outcome prediction can be not only useless but potentially fatal. We aimed to evaluate the out-of-sample validity of a recently…
View details →Daubney ER, Flatley C, Hwang LD et al. · 2025 · Behavior genetics
Despite significant advances in pre- and postnatal care over the last century, adverse pregnancy related events still occur frequently. We used Mendelian randomisation (MR) to investigate potential causal effects of the mother's and fetal…
View details →Groncki R, Beaudry JL, Sauer JD · 2021 · Memory (Hove, England)
The way in which individuals think about their own cognitive processes plays an important role in various domains. When eyewitnesses assess their confidence in identification decisions, they could be influenced by how easily relevant…
View details →Patel KR, Pugh SL, Simko JP et al. · 2026 · Advances in radiation oncology
Purpose The cyclin-dependent kinase inhibitor p27 is a well-profiled modulator of cell cycle progression. Low nuclear p27 levels have been demonstrated to have a negative prognostic impact on outcomes in patients undergoing prostatectomy.…
View details →Fu CK, Lee HT, Yang YC et al. · 2025 · In vivo (Athens, Greece)
Background/aim Gastric adenocarcinoma (GACA) remains a major global health concern, particularly in Asia, due to its poor prognosis and complex etiology. The interaction between genetic factors and environmental exposures, such as smoking,…
View details →Papadopoulos E, Rozenberg D, Wong AKO et al. · 2025 · PloS one
Background Skeletal muscle index (SMI), grip strength, and physical performance have been shown to predict clinically relevant outcomes in geriatric oncology. However, their predictive ability for chemotherapy toxicity is poorly…
View details →Shook NJ, Oosterhoff B · 2020 · Politics and the life sciences : the journal of the Association for Politics and the Life Sciences
Disgust has been consistently associated with greater political conservatism. Two explanations have been proposed for this link. According to a pathogen threat model, disgust serves a pathogen-avoidance function, encouraging more…
View details →Centorame G, Warrington NM, Hemani G et al. · 2025 · Behavior genetics
Breastfeeding is hypothesised to benefit child health and cognitive functioning by providing long-chain polyunsaturated fatty acids, which are essential for brain development. In 2007, Caspi et al. found evidence in two cohorts for an…
View details →Torchiano A, Roberts B, Haroz R et al. · 2025 · The western journal of emergency medicine
Introduction Prescribing patients buprenorphine from the emergency department (ED) is recommended by multiple organizations. However, it is unclear how best to encourage physicians to prescribe buprenorphine from the ED. Our objectives in…
View details →Shen CY, Li CP, Yu JT et al. · 2026 · In vivo (Athens, Greece)
Background/aim Resveratrol, a polyphenolic compound found in grapes, berries, and peanuts, has been linked to antioxidant, anti-inflammatory, and vasoprotective effects. Yet, evidence from randomized controlled trials (RCTs) remains…
View details →Liu J, Catanzariti MJ, Nguyen-Hao HT et al. · 2026 · Journal of neuropathology and experimental neurology
Alcohol use disorder (AUD) is characterized by an inability to stop consuming alcohol. Neuroimaging studies of patients with AUD show mild grey and white matter atrophy, while pathological studies suggest that atrophy is restricted to the…
View details →Udry J, Barber SJ · 2025 · Cognition
Inoculation interventions aim to improve discernment between true and false information, but their effectiveness with older adults is unknown. It is also unknown whether inoculation interventions are effective when misinformation is…
View details →Belmaker RH · 2025 · Pharmaceuticals (Basel, Switzerland)
Lithium was the first discovered mood stabilizer for bipolar disorder. However, several antiepileptics such as valproate and carbamazepine have also proven to be mood stabilizers in all phases of bipolar disorder with profiles barely…
View details →French B, Chiaro NVD, Holmes NP · 2022 · Experimental brain research
The grating orientation discrimination task (GOT) is a sensitive and reliable measure of tactile spatial resolution, or acuity. We used the GOT in three experiments to investigate the effects of hand posture and hand visibility on spatial…
View details →Johnson B, Addolorato G, Lesch O et al. · 2023 · Frontiers in psychiatry
A core principle in the pursuit of scientific knowledge is that science is self-correcting and that important results should be replicable. Hypotheses need to be reinforced, adjusted, or rejected when novel results are obtained.…
View details →Ferhatlar ME, Cumhur BA, Koca Y et al. · 2026 · European journal of trauma and emergency surgery : official publication of the European Trauma Society
Purpose The aim of this study is to prospectively compare the diagnostic performance of the PECARN, CATCH, and CHALICE clinical decision rules in pediatric patients presenting with minor head trauma, within a rural secondary-level…
View details →Zarghami Y, Rad MG, Mafeld S et al. · 2026 · Scientific reports
Continual automated pain detection from facial expressions using computer vision during procedural sedation could optimize sedation dose titration and minimize pain. A prospective observational study was conducted. Participants' faces were…
View details →Balraam Kv V, Nayak AR, Dass J et al. · 2026 · Journal of pediatric hematology/oncology
Background Systemic mastocytosis (SM) with associated acute myeloid leukemia (AML) is a rare malignancy usually linked to KIT p.D816V mutations. Observations We report a 17-year-old female with RUNX1::RUNX1T1-positive AML and florid mast…
View details →Slis A, Parrell B · 2026 · Journal of cognitive neuroscience
Sensory errors, mismatches between predicted sensory outcomes of movement and reafferent sensory feedback, drive changes in the feedforward control of future motor behavior that correct for those errors. Across a wide variety of motor…
View details →Kaiser A, Resasco J, Dee LE · 2026 · Nature ecology & evolution
Urban environments pose unique challenges for understanding drivers of biodiversity change, as fragmented land ownership makes traditional biodiversity monitoring and randomized experiments logistically difficult. While participatory…
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