In vivo cartilage tissue engineering
B. Gurer; S. Cabuk; O. Karakus; N. Yilmaz; C. Yilmaz · 2018 · Journal of Orthopaedic Surgery and Research
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Abstract Background Biologic treatment options for cartilage injuries require chondrocyte expansion using cell culture. Clinical application is accomplished in two surgical sessions and is expensive. If isolation of chondrocytes and stimulus for proliferation and extracellular matrix synthesis can be achieved in vivo, the treatment can be performed in one session and the cost can be reduced. Methods A 2.5-cm diameter full-thickness chondral defect was created in the knees of five groups of sheep. In one group, some of the chondral tissues obtained from the creation of the defect were diced int
Abstract by B. Gurer; S. Cabuk; O. Karakus; N. Yilmaz; C. Yilmaz, Journal of Orthopaedic Surgery and Research (2018) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.1186/s13018-018-0823-0