Negative / Null Result ReportMedicine
Dijksterhuis J, Hurmuz MZM, van Dartel D et al. · 2026 · European geriatric medicine
Purpose Older hip fracture patients are often frail, complicating their recovery trajectories. Insight into patients' resilience may help in getting more understanding of their predicted recovery and adjusting their treatment plan…
View details →Negative / Null Result ReportOpen accessMedicine
Shanmugasundaram D, Wang RA · 2026 · Journal of toxicology
Objective Zylaria comprises a blend of botanical components, including Xylaria Nigripes (mycelium), Cuscuta Chinensis (seed) and Panax Notoginseng (root). This study aimed to evaluate the potential toxicity of Zylaria when administered…
View details →Negative / Null Result ReportOpen accessMedicine
Motomura T, Higashi M, Hattori A et al. · 2026 · Internal medicine (Tokyo, Japan)
Objective Hyperuricemia is associated with cardiovascular disease and chronic kidney disease (CKD). Dotinurad is a new uricosuric drug that has not been evaluated in clinical trials in patients with advanced CKD (CKD G3b-G5). This study…
View details →Negative / Null Result ReportMedicine
Pedersen TA, Mori Y, Botteri E et al. · 2026 · Endoscopy
Background The effect of computer-aided detection (CADe) on performance of endoscopists with different experience levels is not well understood. This study assessed whether CADe use promotes learning or deskilling. Methods We performed a…
View details →Negative / Null Result ReportMedicine
Hoskens S, Bamps K, Herteleer M · 2026 · European journal of orthopaedic surgery & traumatology : orthopedie traumatologie
Objectives The percutaneous placement of iliosacral (IS) and transsacral (TS) screws has become a standard practice for the treatment of pelvic fractures. Due to the complex sacral anatomy, accurate screw placement is essential to avoid…
View details →Negative / Null Result ReportOpen accessMedicine
Muñoz-Vendrell A, Arroyo-Pereiro P, León I et al. · 2026 · Journal of neurology
Background Subcutaneous natalizumab offers greater convenience than intravenous administration, but pharmacokinetic differences have raised concerns about potential subclinical disease activity. Serum neurofilament light chain (sNfL) and…
View details →Failed Experiment ReportMedicine
Boegl M, Kasper I, Dewailly D et al. · 2026 · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology
Objective Up to 50% of women with functional hypothalamic amenorrhea (FHA) exhibit polycystic ovarian morphology (PCOM) on ultrasound. We aimed to compare the hormonal response to ovulation induction with pulsatile GnRH therapy in FHA…
View details →Negative / Null Result ReportMedicine
Zhao L, Zeng C, Jia X et al. · 2026 · Medicine
Breast cancer (BC) has the highest cancer incidence and mortality in women worldwide, and the relationship between serum enzymes and BC has been inconsistent in previous observational studies. In this paper, 2-sample Mendelian…
View details →Negative / Null Result ReportMedicine
Al-Mohana RAAM, Jianping H, Alhammadi MS et al. · 2026 · Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery
Objective To elucidate the pattern and extent of long-term condylar adaptation within the temporomandibular joint (TMJ) following mandibular setback by bilateral sagittal split osteotomy (BSSO) in patients with mandibular prognathism, with…
View details →Negative / Null Result ReportMedicine
Kubota H, Makino Y, Yoshida M et al. · 2026 · International journal of legal medicine
Background It is important to understand post-mortem changes in post-mortem computed tomography (PMCT) image interpretation. Only a few studies have focused on the eyeballs. This study aimed to clarify the changes in eyeball findings on…
View details →Negative / Null Result ReportOpen accessMedicine
Lu Y, Shu L, Liu C et al. · 2026 · Frontiers in cardiovascular medicine
Background Ethanol infusion of the vein of Marshall (EIVOM) has emerged as a promising adjunct to pulmonary vein isolation (PVI) for atrial fibrillation (AF). Methods Patients undergoing catheter ablation for persistent AF (>3 months) were…
View details →Negative / Null Result ReportMedicine
Kocaman Y, Yanmaz LE · 2026 · Veterinary ophthalmology
Purpose This study aimed to evaluate the effects of ivermectin administration on aqueous tear production and ocular surface health in dogs and to investigate its potential association with quantitative keratoconjunctivitis sicca (KCS).…
View details →Negative / Null Result ReportMedicine
Lin YJ, Chen QY, Zhao SY et al. · 2026 · Retina (Philadelphia, Pa.)
Purpose This study investigated the clinical characteristics and prognosis of rhegmatogenous retinal detachment (RRD) in patients with implantable collamer lens (ICL). Methods A retrospective review was conducted of medical records from…
View details →Negative / Null Result ReportMedicine
Treanor M, Zbozinek TD, Rosenberg BM et al. · 2025 · Journal of consulting and clinical psychology
Objective To investigate the role of extinction learning and habituation by comparing inhibitory retrieval to habituation-focused exposure for social anxiety and panic disorder. Method In this assessor-blinded, parallel-group, two-arm…
View details →Negative / Null Result ReportMedicine
Demirel N, Yildiz B, Demir M · 2026 · Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
Objective To evaluate the safety and efficacy of CDK4/6 inhibitors in combination with hormone therapy, and to investigate potential predictive markers of treatment in metastatic breast cancer (MBC). Study design An observational study.…
View details →Negative / Null Result ReportMedicine
Bachelard L, Blanc N, Michel A · 2026 · BMJ supportive & palliative care
Objective Breast cancer surgery often leads to a high burden of distressing symptoms, underscoring the need for supportive care to help patients throughout the perioperative period. This pilot study aimed to evaluate the feasibility,…
View details →Negative / Null Result ReportOpen accessMedicine
Mosch B, Diers M · 2026 · Pain reports
Introduction Since the outbreak of COVID-19, many studies have investigated long-term consequences associated to the pandemic. Undoubtedly, restrictions and changes in everyday life during that time have had a broad impact on mental health…
View details →Negative / Null Result ReportMedicine
Achar A, Houser P, Cherian J et al. · 2026 · Lupus
ObjectiveTo determine the long-term outcomes of patients with moderate-severe pediatric systemic lupus erythematosus (pSLE) treated with systematic administration of combination rituximab (RTX) and cyclophosphamide (CYC) at our…
View details →Negative / Null Result ReportOpen accessMedicine
Burger C, Pirotte M, Ray K et al. · 2026 · The western journal of emergency medicine
Introduction Emergency physicians commonly receive feedback in the form of performance metrics such as patients seen per hour. Reviewing metrics has been associated with increased stress and burnout. Although effects on efficiency have…
View details →Negative / Null Result ReportMedicine
Jang YE, Kim Y, Kim HI et al. · 2026 · Journal of endodontics
Introduction Hydraulic calcium silicate cement-based sealers (CSC sealers) are now frequently used with warm vertical compaction in root canal treatment. However, the impact of heat on the biological properties of CSC sealers remains…
View details →Negative / Null Result ReportMedicine
Nakano H, Shiinoki T · 2026 · Journal of neuro-oncology
PURPOSE: The radiosensitivity index (RSI) is a transcriptomic predictor of intrinsic radiosensitivity. The longitudinal behavior of the RSI in glioma and its variation across intratumoral cellular states have been unknown. We investigated…
View details →Abandoned HypothesisOpen accessMedicine
Chang TP, Kuo YH, Bery AK · 2026 · Frontiers in neurology
Background Dizziness is common in older adults, and often presents a diagnostic challenge. Vestibular function declines with age, but the prevalence and diagnostic explanatory value of mild vestibular loss in isolation (i.e., the clinical…
View details →Negative / Null Result ReportMedicine
Silva TR, Poínhos R, Oliveira BMPM et al. · 2026 · The British journal of nutrition
While rapid four-compartment (4C) models have demonstrated cross-sectional validity in diverse populations, including athletes, their longitudinal validity remains unverified. This study aims to evaluate the longitudinal validity of…
View details →Negative / Null Result ReportMedicine
Hugueny J, de Ricolfis A, Johnson N et al. · 2025 · Thrombosis research
Objective This review aimed to synthesize recent data on venous thromboembolism (VTE) risk in the context of masculinizing hormone therapy with testosterone. Methods An electronic search was performed in MEDLINE/PubMed without date…
View details →Negative / Null Result ReportMedicine
Rhodes J, Leach A · 2026 · Journal of sport & exercise psychology
Imagery is widely used in sport, but its effectiveness depends on how it is structured and the range of senses engaged. This study compared Functional Imagery Training-a multisensory, motivational intervention-with single-sense internal…
View details →Negative / Null Result ReportMedicine
Anthuparambil ND, Timmermann S, Dargasz M et al. · 2026 · The Journal of chemical physics
The effect of lowered pH on the thermal gelation behavior of hen egg yolk was investigated over the temperature range of 58-72 °C using low-dose X-ray photon correlation spectroscopy in ultra-small-angle X-ray scattering geometry.…
View details →Negative / Null Result ReportMedicine
Tikhonova P, Mekonnen Z, Belanger KD et al. · 2026 · Communications medicine
Background Mass deworming programs using anthelmintic drugs are a common public health strategy for controlling soil-transmitted helminth (STH) infections in high-risk, low-income countries. However, whether routine deworming induces…
View details →Negative / Null Result ReportMedicine
Ma CY, Chen J, Fu Y et al. · 2026 · BMC medical education
Background Competence in radiation oncology is still commonly expected to emerge through apprenticeship, although essential tasks such as target delineation, treatment-plan review, and multidisciplinary reasoning are not reliably sampled…
View details →Negative / Null Result ReportMedicine
Burnet G, Vasic I, Sauaia A et al. · 2026 · Journal of surgical education
Objective To determine the efficacy of cognitive behavioral therapy (CBT) on stress, anxiety, burnout, and depression in surgical interns and to determine the optimal timing of CBT. Our hypothesis was that CBT could improve each of these…
View details →Negative / Null Result ReportOpen accessMedicine
Mehraj F, Bhat MA, Mangulkar A et al. · 2025 · Journal of pharmacy & bioallied sciences
Introduction In recent years, there has been a great deal of interest in research because of the changes that the extraction of premolars has caused to the structures surrounding of the upper airway. This is because it's thought that these…
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