12,241 real negative results, null findings, and replication failures in Medicine. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Ho K, Adjei-Afriyie O, Carmona-Martinez R et al. · 2026 · Brain communications
Congenital myasthenic syndromes (CMS) are a group of rare disorders characterized by fatigable muscle weakness and caused by impaired neuromuscular junction (NMJ) function. CMS symptoms are highly variable, but it can be detrimental and…
View details →Morales AA, Camarena V, Peart L et al. · 2026 · Scientific reports
Geleophysic dysplasia (GD) is a rare genetic disorder characterized by short stature, joint contractures, and cardiopulmonary complications, with early mortality, and linked to mutations in ADAMTSL2 (GD1), FBN1 (GD2), or LTBP3 (GD3) genes.…
View details →Halko ML, Halonen J, Laukkanen M et al. · 2026 · Cognition & emotion
Political and economic challenges, amplified by social media algorithms, are increasingly polarising how people receive and evaluate information. This study examines how political views and immediate emotional reactions shape the perceived…
View details →Araga Y, Nakamura Y, Sugita C et al. · 2026 · Rinsho shinkeigaku = Clinical neurology
The patient was a 30-year-old man who was admitted to our department 2 months after the onset of anterograde amnesia. Cognitive function tests indicated memory impairment only. MRI FLAIR images of the head showed a high signal in the…
View details →Pham TN, Chamseddine I, Lebhertz D et al. · 2026 · Physics in medicine and biology
Introduction. Radiation-induced optic neuropathy (RION) is a rare but functionally-disabling complication of radiotherapy for brain and head/neck tumors. Even with modern proton therapy and adherence to dose constraints, about 6% of…
View details →Shi L, Li Y, Li C et al. · 2026 · International journal of clinical oncology
Background Comparative evidence for neoadjuvant chemoimmunotherapy (NCIT) versus neoadjuvant immunotherapy combined with chemoradiotherapy (NICRT) in locally advanced esophageal squamous cell carcinoma (ESCC) is limited. We compared…
View details →Hatipoğlu Ö, Başar Ö, Mağat G et al. · 2026 · Scientific reports
Accurate detection of overhanging dental restorations on bitewing radiographs is clinically important but remains challenging due to subtle marginal discrepancies. This study aimed to develop and compare deep learning-based instance…
View details →Packet B, Van Severen R, Cattani L et al. · 2026 · European journal of obstetrics, gynecology, and reproductive biology
Objectives To study the association between the subpubic arch angle and area, the latter a novel estimator of maternal pelvic outlet dimensions, and postpartum anal incontinence. Methods Convenience sample from a prospective observational…
View details →Aglen T, Matre KH, Selles RW et al. · 2026 · Journal of hand therapy : official journal of the American Society of Hand Therapists
Background Collagenase treatment can improve finger extension and hand function in patients with Dupuytren's disease. The role of hand therapy in enhancing or prolonging these effects remains unclear. Purpose The primary aim was to examine…
View details →Steen JP, Jaiswal KS, Dilipkumar J et al. · 2026 · The journal of pain
The measurement performance of the Short-Form Brief Pain Inventory (BPI-SF) across IASP-recognized pain mechanisms remains unclear. We evaluated the reliability and structural validity of BPI-SF across clinician-assigned predominant…
View details →Ghofranian A, Baird M, Reckhow J et al. · 2026 · Minerva obstetrics and gynecology
Background Luteal phase E2 priming is commonly used in patients with DOR to 30 synchronize follicular development before controlled ovarian hyperstimulation (COH). Some protocols 31 incorporate a GnRH antagonist during the luteal phase to…
View details →Kongkhuntian P, Aunmeungtong W, Khongkhunthian P · 2026 · Clinical implant dentistry and related research
Objective This study aimed to compare the effect of PTFE tape wrapping and PTFE-coated titanium alloy screws on the removal torque after cyclic loading and on preload values under repetitive tightening. Methods A total of 60 titanium…
View details →Tournu E, Tourdot-Maréchal R, Coelho C · 2026 · International journal of food microbiology
Phytosanitary and copper treatments in viticulture are essential to protect vines against biotic and abiotic stresses. However, residues from these treatments can persist in grape musts and wines, potentially raising risks to consumer…
View details →McClure Z, Fuller-Tyszkiewicz M, Messer M et al. · 2026 · The International journal of eating disorders
Objective Although a range of evidence-based treatments for eating disorders exist, treatment response varies substantially. The ability to match individuals to a treatment which they are most likely to benefit from may help improve…
View details →Khatri D, Poudel S, Pun Magar L et al. · 2026 · Frontiers in plant science
Soybean meal quality for monogastric animals is limited by low sulfur-containing amino acids, especially methionine and cysteine, while oil oxidative stability is restricted by the high polyunsaturated fatty acid content. This two-year…
View details →Wall A, Fisher JA, Watkinson EK et al. · 2026 · Australian critical care : official journal of the Confederation of Australian Critical Care Nurses
Background Early warning scores like the National Early Warning Score 2 (NEWS2) identify patient deterioration but do not incorporate clinician-intuitive assessment. Previous research suggests facial expressions can be critical indicators…
View details →Larsen LJ, Dornbusch MR, Hines-Snider C et al. · 2026 · Plant disease
Seed rot and damping-off of alfalfa ( Medicago sativa L.) is caused by a soilborne disease complex resulting in thin initial stands of plants with continuing damage during wet soil conditions decreasing forage yields and winter survival.…
View details →Giese H, Gaissmaier W, Kuss O et al. · 2026 · Medical decision making : an international journal of the Society for Medical Decision Making
BackgroundTime-to-event outcomes from randomized controlled trials (RCTs) are often communicated without clearly conveying how treatment effects evolve over time. This can limit clinicians' ability to interpret results and support patient…
View details →Müller D, Gillani A, Hirschmann MT et al. · 2026 · Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA
Purpose Accurate risk adjustment in total knee arthroplasty (TKA) is essential for outcome prediction and quality assessment. Most existing prediction models rely solely on patient demographics and comorbidities and do not account for…
View details →Jiang PP, Huang HY, Zhao L et al. · 2026 · Pediatric research
Background Fortification of human milk for very preterm infants (VPIs) with alternatives to conventional bovine milk-based fortifiers remains minimally studied. This trial tested whether fortification with protein-rich bovine colostrum…
View details →Bourdin A, Dureau S, Algret N et al. · 2026 · Retina (Philadelphia, Pa.)
Purpose To report safety outcomes of transscleral fine-needle aspiration biopsy (FNAB) followed by irradiation for uveal melanoma (UM) in a tertiary ocular oncology center over 10 years, and assess whether FNAB modified the overall…
View details →Stanula A, Strzała M, Sadowski W et al. · 2026 · Scientific reports
Post-activation performance enhancement (PAPE) has been proposed as an acute strategy to improve explosive performance, yet its effects on sprint-swimming performance remain unclear, particularly when individualized recovery timing is…
View details →Papadogiorgou G, Koskinioti P, Rodovitis V et al. · 2026 · Bulletin of entomological research
Thermal stress can affect the field performance of sterile males used in the sterile insect technique (SIT). We tested whether adding autoclaved Enterobacter as a dietary supplement improves thermal tolerance in sterile Vienna 8 genetic…
View details →Hachiro K, Takashima N, Kamiya K et al. · 2026 · Circulation reports
Background The effectiveness of multiple arterial grafting (MAG) for hemodialysis (HD) patients is unclear. Methods and results We retrospectively analyzed 149 HD patients who underwent either MAG (n=97) or single arterial grafting (SAG)…
View details →Xiang J, Hou J, Zhang H · 2025 · Endocrine-related cancer
Follicular thyroid carcinoma (FTC) and oncocytic thyroid carcinoma (OTC) are distinct entities with differing biological behaviors, yet optimal surgical and radioactive iodine (RAI) therapy management remains debated. Demographic,…
View details →Lienert M, Stadler L, Kipfer N et al. · 2026 · Veterinary journal (London, England : 1997)
Objectives To investigate the effect of electroacupuncture on postoperative analgesia in dogs undergoing Tibial Tuberosity Advancement surgery. We hypothesise that acupuncture will reduce pain scores and the need for rescue analgesia…
View details →Zaki HF, Bishri J, Abdul Muqtadir M et al. · 2026 · Experimental eye research
Background Cone-rod dystrophy (CORD) and achromatopsia (ACHM) are inherited retinal dystrophies for which conventional adeno-associated virus (AAV) gene augmentation has important limitations, particularly in autosomal-dominant…
View details →Blokzijl J, Kuijlaars IAR, Pisters MF et al. · 2026 · Haemophilia : the official journal of the World Federation of Hemophilia
Introduction The Haemophilia Activities List (HAL) is a disease-specific patient-reported outcome measure (PROM) that is widely used in both healthcare and research in people with inherited bleeding disorders (PWBD), but information on…
View details →Vardanega R, Lüdtke FL, Loureiro L et al. · 2026 · Journal of agricultural and food chemistry
This study investigated whether coencapsulation of cannabidiol (CBD) and piperine (PIP) in food-grade nanostructured lipid carriers (NLCs) enhances the CBD oral bioavailability. NLCs containing long-chain fatty acids were formulated with…
View details →Unal RU, Ozhan O, Balkaya ES et al. · 2026 · Scientific reports
Sepsis frequently leads to cardiac dysfunction driven by oxidative stress (OS), inflammation, and conduction abnormalities. Nebivolol (NEB), a selective β1-blocker with vasodilatory and antioxidant properties, has shown organ-protective…
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