Negative / Null Result ReportMedicine
El-Haffaf I, Laverdière J, Albert M et al. · 2024 · Canadian journal of physiology and pharmacology
Augmented renal clearance (ARC) is commonly described in critically ill patients, making drug pharmacokinetics even harder to predict in this population. This case report displays the value of therapeutic drug monitoring (TDM) of…
View details →Negative / Null Result ReportOpen accessMedicine
Zöller M, Mastalerz M, Dick E et al. · 2026 · Scientific reports
The airway epithelium is the first site of injury from cigarette smoke (CS), a major risk factor for chronic lung disease including idiopathic pulmonary fibrosis (IPF). Here, we report the first intracellular proteomic analysis of CS…
View details →Negative / Null Result ReportOpen accessMedicine
Kawaguchi Y, Hana T, Hasegawa H et al. · 2025 · Journal of neurosurgery. Case lessons
Background High-grade gliomas, particularly isocitrate dehydrogenase-wildtype glioblastomas (GBMs), are highly aggressive brain tumors with limited treatment options and poor outcomes. A subset of these tumors, including epithelioid GBM,…
View details →Negative / Null Result ReportMedicine
Pletta DR, Mayer KH, Chen JT et al. · 2024 · Transgender health
Purpose Transgender and nonbinary adults (TNB) are disproportionately burdened by sexually transmitted infections (STI) and the human immunodeficiency virus (HIV). This study investigated whether gender-affirming hormone therapy was…
View details →Replication FailureOpen accessMedicine
Gangeri L, Alfieri S, Anselmi V et al. · 2025 · Tumori
Background As part of the improvement plan of the Organisation of European Cancer Institutes at the Fondazione IRCCS Istituto Nazionale dei Tumori of Milan (INT) a Committee composed of patients, caregivers, and representatives of patient…
View details →Negative / Null Result ReportMedicine
Sambol S, Suleyman E, Scarfo J et al. · 2023 · Acta psychologica
The unity/diversity framework, originally published by Miyake et al. (2000) has become the most cited model of executive functioning. Consequently, when researchers operationalise executive function (EF) they often exclusively assess the…
View details →Negative / Null Result ReportOpen accessMedicine
Murugesan M, Niveditha LP, Sindhu ER et al. · 2026 · Hematology, transfusion and cell therapy
Introduction Derived hematological indices reflect immune activation, but their dynamics during the plerixafor era and their predictive value for stem cell yield remain unclear. Objectives To assess changes in derived hematological…
View details →Negative / Null Result ReportOpen accessMedicine
Kumar S, Kumar A, Ameta N et al. · 2026 · Annals of cardiac anaesthesia
Background In-hospital cardiac arrest demands immediate response to improve survival outcomes. The Code Blue Response System (CBRS) was designed to streamline emergency interventions by reducing response times. This study aimed to evaluate…
View details →Negative / Null Result ReportOpen accessMedicine
Minion S, Kiene J, Dellavalle R · 2023 · JMIR dermatology
Gender disparities exist across all facets of academic medicine including within the editorial boards of dermatology journals. Only 22% of these editorial boards comprised women, even though 51% of full-time, faculty dermatologists are…
View details →Negative / Null Result ReportOpen accessMedicine
Bloch RJ, Traficante M, Mariot V et al. · 2025 · Neuromuscular disorders : NMD
Facioscapulohumeral muscular dystrophy is a progressive muscle disorder that is likely linked to aberrant DUX4 expression. Losmapimod, a p38 kinase inhibitor, was utilized to suppress DUX4 and its downstream effects. Phase I/II clinical…
View details →Negative / Null Result ReportMedicine
Garg AX · 2026 · Annals of internal medicine
Clinical impact ratings GIM/FP/GP: [Formula: see text] Critical Care: [Formula: see text] Nephrology: [Formula: see text].
View details →Negative / Null Result ReportMedicine
Dodd TS, Borzak S · 2026 · Annals of internal medicine
Clinical impact ratings GIM/FP/GP: [Formula: see text] Cardiology: [Formula: see text] Hematology: [Formula: see text].
View details →Negative / Null Result ReportMedicine
Jain S, Jha AK, Chawla D et al. · 2026 · Indian journal of pediatrics
OBJECTIVES: To determine the effect of prone positioning on the duration of respiratory support in neonates receiving non-invasive mode of ventilation. METHODS: This open label randomized controlled trial was conducted in the NICU of a…
View details →Negative / Null Result ReportOpen accessMedicine
Brasher MI, Patil MS · 2026 · Acta paediatrica (Oslo, Norway : 1992)
The LAKANA trial: a randomized control trial evaluating the impact of mass administration of azithromycin to infants 1 to 11 months of age in Mali showed no reduction in mortality.
View details →Negative / Null Result ReportOpen accessMedicine
Legnani C, Ventura A, Oriani G · 2026 · Journal of clinical practice and research
A retrospective study was conducted to evaluate the need for perioperative autotransfusions and the amount of blood loss by comparing patients receiving different tranexamic acid (TXA) regimens following total joint replacement (TJR). A…
View details →Negative / Null Result ReportMedicine
Greenway RR, Coulter AA, Zhang D et al. · 2026 · Journal of medicinal food
Gallic acid, a catechin polyphenol in tea, completely inhibited angiogenesis in assays of human tissue at 10 -3 M. Psoriasis is a skin disease caused by excessive secretion of angiogenenic factors by keratinocytes and stromal skin cells.…
View details →Negative / Null Result ReportMedicine
Fantasia ME, Penick CA · 2026 · Journal of economic entomology
Climate change intensifies drought frequency, posing risks to pollinators both directly and indirectly through changes in floral resource availability. We tested how water limitation alters pollinator-relevant floral traits, visitation,…
View details →Negative / Null Result ReportMedicine
Rebel HG, de Gruijl FR · 2026 · Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology
We reported earlier that adult FabplCre;Apc 15lox/+ mice with either daily UV exposure or vitamin D supplementation developed not significantly fewer intestinal tumours but less tumour bulk (reduced outgrowth) than control mice that…
View details →Negative / Null Result ReportMedicine
De Grandi D, LuTheryn G, Stoffels M et al. · 2026 · Ultrasound in medicine & biology
Objective Dental biofilms are responsible for the majority of oral cavity diseases (e.g., caries, periodontitis and gingivitis). In this work, we evaluate the effects of therapeutic ultrasound on a Streptococcus mutans biofilm model. The…
View details →Negative / Null Result ReportMedicine
Uyoga MA, Baumgartner J, Malan L et al. · 2026 · The Journal of nutrition
Background Young South African women face a double-burden of overweight or obesity and iron deficiency, with the former predicting the latter. Omega-3 long-chain polyunsaturated fatty acid (LCPUFA) supplementation can reduce inflammation.…
View details →Negative / Null Result ReportMedicine
Lim LS · 2025 · Annals of internal medicine
Clinical impact ratings GIM/FP/GP: [Formula: see text] Cardiology: [Formula: see text] Geriatrics: [Formula: see text] Public Health: [Formula: see text].
View details →Negative / Null Result ReportMedicine
Pak MA, Güzel Altıntaş F, Okyar G et al. · 2026 · Scientific reports
Anastomotic leakage is a serious complication after colorectal surgery. Smoking is known to impair anastomotic healing. The use of electronic cigarettes is increasing worldwide, and information about their effects on wound healing remains…
View details →Negative / Null Result ReportMedicine
Amoroso F, Miere A, Kodjikian L et al. · 2026 · Retina (Philadelphia, Pa.)
Purpose This study aimed to compare exudative recurrence features detected by optical coherence tomography angiography (OCTA) with those identified by spectral domain optical coherence tomography (SD-OCT), considered the gold standard, and…
View details →Negative / Null Result ReportMedicine
Kalli AJ, Mäkelä P, Huhtala H et al. · 2026 · Acta anaesthesiologica Scandinavica
Background Sternotomy causes substantial postoperative pain. Recently, several less invasive nerve blocks have been described that are safer to use even on anticoagulated patients. This study aims to evaluate early pain management using…
View details →Negative / Null Result ReportMedicine
Quan S, Xie H, Zhang D et al. · 2026 · Esophagus : official journal of the Japan Esophageal Society
Background Postoperative chylothorax is a serious complication following esophagectomy. The efficacy of thoracic duct ligation (TDL) for chylothorax prevention is controversial. This study aimed to evaluate the impact of TDL on chylothorax…
View details →Negative / Null Result ReportMedicine
Osmani R, Cavallotto L, William N et al. · 2026 · Cryobiology
Cryopreservation of zebrafish embryos remains challenging due to their low tolerance for cryoprotectant exposure and their susceptibility to lethal ice formation. Ice recrystallization inhibitors (IRIs) such as…
View details →Negative / Null Result ReportMedicine
Wick B, Sahibzada O, Cherner A et al. · 2026 · Journal of vascular surgery. Venous and lymphatic disorders
Objective The optimal clinical management of isolated distal deep venous thrombosis (IDDVT) remains controversial as the benefits of routine anticoagulant therapy are not clearly defined amid the risk of bleeding events. Our study aimed to…
View details →Negative / Null Result ReportMedicine
Hetherington A, Bauer L, Rablin S et al. · 2026 · Australasian emergency care
Background Acute wheeze is a common emergency department presentation among pre-school aged children. Innovative models of care that safely optimise treatment and streamline patient flow are needed. A nurse-led stretching of inhaled…
View details →Negative / Null Result ReportMedicine
Agweyu A, Mwaniki P, Menon V et al. · 2026 · Nature medicine
Rigorous evidence on the performance of large language models (LLMs) in real-world, low-resource clinical settings remains limited. Here we conducted a pragmatic, cluster-randomized trial in 16 primary care facilities in Kenya. Clinical…
View details →Negative / Null Result ReportMedicine
Khan S, Simmons KL, Khan S et al. · 2026 · Orbit (Amsterdam, Netherlands)
Purpose To determine whether prophylactic antibiotic administration following the development of an orbital floor fracture or after orbital floor fracture repair is associated with a reduced risk of orbital or periorbital cellulitis.…
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