Design Matters: How Methodological Decisions May Have Shaped the Findings of CREST-2.
Chimowitz MI · 2026 · Stroke
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
CREST-2 (Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trials) comprised 2 parallel randomized trials in asymptomatic carotid stenosis comparing medical management alone with medical management plus…
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Metadata source: Europe PMC · DOI 10.1161/strokeaha.125.054876