12,375 real negative results, null findings, and replication failures in Medicine. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Polauke E, Stage Sø J, Carl H et al. · 2024 · Journal of environmental management
Ambitious to fulfill the European Water Framework Directive obligations, the European governments support projects to rehabilitate lakes with poor water quality. However, most lake restorations having relied on biomanipulation by fish…
View details →Li J, Zhou J, Ha Q et al. · 2026 · Frontiers in cardiovascular medicine
Objective Obesity is an independent risk factor for cardiovascular diseases and elevated mortality, yet the underlying mechanisms remain incompletely understood. Impaired endothelium-dependent relaxation is an early manifestation of…
View details →Shankie-Williams K, Day M, Dowland S · 2026 · Biology open
There is a critical need for novel non-hormonal contraceptives. Zinc-based intrauterine devices (IUDs) demonstrate 100% efficacy in rats, yet the mechanism remains unclear. We investigated whether zinc targets sperm, embryos, or the…
View details →Zaidi S, Zoya M, Ishrat M et al. · 2026 · Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
The study aimed to evaluate delays in emergency department (ED) arrival among stroke patients and to identify demographic factors that contribute to these delays. It was a cross-sectional study conducted at the Department of Neurology,…
View details →Rowhani M, Hörmannstorfer-Fessl K, Kastner M et al. · 2026 · Respiratory medicine
Background Dry powder inhalers (DPIs) prescribed for respiratory diseases require patients to generate sufficient peak inspiratory flow (PIF) for optimal drug delivery to the airways. However, information is scarce regarding PIF of asthma…
View details →Moss AS, Nguyen QG, Iyer P · 2026 · Clinical rheumatology
Background Patient education materials are vital to health education and, according to the American Medical Association (AMA), should not be written above a 6th grade reading level (Weiss 2003). We aim to assess American College of…
View details →Carnes N, McAnany J, Khodr Z et al. · 2026 · Journal of attention disorders
Objective Attention-deficit/hyperactivity disorder (ADHD) can potentially disqualify individuals for military service. However, some past research suggests the performance of individuals with ADHD in military service may be comparable to…
View details →Heilmann F, Langsdorf LE, Schubert T · 2026 · Psychological research
This study investigated how stimulus material and effector specificity influence interference control (a form of inhibitory control) in adolescent players. Ninety-one males aged 15-18 years (28 handball players, 34 soccer players, 29…
View details →DeBoest A, Holley C, Hickey M et al. · 2026 · American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
Purpose To determine the impact of pharmacist intervention with real-time continuous glucose monitors (rtCGMs) on glycated hemoglobin (HbA1c) levels and the number of pharmacist touchpoints compared to standard of care (SOC). Methods…
View details →Phan TH, Phan MQ · 2026 · La Clinica terapeutica
Background Residual cardiovascular risk after acute myocardial infarction (AMI) is driven not only by dyslipidemia but also by systemic inflammation. High-sensitivity C-reactive protein (hs-CRP) and low-density lipoprotein cholesterol…
View details →Zhang Z, Luo Z, Lai M et al. · 2026 · Optics express
To address the severe intersymbol interference (ISI) in high-speed optical transmission systems, this paper proposes a memory-augmented neural network equalizer (MANNE). Building upon the architecture of a traditional neural network…
View details →Xiao H, Zeng X, Pang Q et al. · 2026 · Transplant immunology
Background Sodium-glucose cotransporter-2 inhibitors (SGLT2i) yield additional cardiorenal benefits beyond glycemic control. Emerging evidence suggests that SGLT2i have potential benefits in organ transplantation, though causal…
View details →Park M, Park H, Baek IH et al. · 2026 · Journal of patient safety
Objectives Erythropoiesis-stimulating agents (ESAs), classified as long-acting or short-acting, is a primary treatment for anemia in chronic kidney disease and chemotherapy. Given ongoing safety concerns regarding cardiovascular events and…
View details →Tulsian V, Kant R, Patnaik I et al. · 2026 · Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology
Background and objectives Helicobacter pylori infection is highly prevalent globally. Standard bismuth quadruple therapy is commonly used in India, but there are growing concerns regarding the emergence of anti-microbial resistance and…
View details →Hong WJ, Huang JM, Liu YH et al. · 2025 · Aesthetic plastic surgery
Background The postauricular injection technique is a needle-based technique that places soft tissue fillers behind the ears into the supra-periosteal plane of the mastoid process of the temporal bone. The resulting clinical effect pushes…
View details →Morris JS, Rajshekhar S, Gremmo G et al. · 2026 · European journal of obstetrics, gynecology, and reproductive biology
Deep endometriosis (DE) is established to cause chronic pelvic pain (CPP), lower urinary tract symptoms (LUTS) and altered bowel function. Although the aim of surgical excision is often to relieve CPP, evidence suggests it could also…
View details →Reiter T, Dörrler AL, Hasenauer N et al. · 2026 · European journal of nuclear medicine and molecular imaging
Introduction Acute myocardial infarction (AMI) triggers local inflammation in the injured myocardium, followed by a systemic inflammatory response of lymphatic organs. This prospective trial (NCT05519735) focused on molecular imaging of…
View details →Shabbir A, Abbas G, Alharby HF et al. · 2026 · International journal of phytoremediation
Heat stress and soil arsenic (As) contamination are resulting in severe decline in crop production around the world. The present experiment aimed to assess physiological and biochemical changes induced by the combination of As and heat…
View details →Son AJ, Rapp E, Wiezorek A et al. · 2026 · JCI insight
Stopping and restarting GLP-1 weight-loss drugs in mice made them less effective over time and increased fat gain compared with continuous treatment.
View details →Cottom JM, Verdoni TJ · 2026 · The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons
Background Total ankle replacement continues to find significantly increased utilization as the technology advances. While there are different systems on the market, most are implanted through an anterior incisional approach just lateral…
View details →El-Haffaf I, Marsot A, Paillault A et al. · 2025 · Canadian journal of physiology and pharmacology
In this study, we evaluate the exposure and pharmacokinetic/pharmacodynamic target attainment of meropenem in critically ill patients. We conducted a prospective observational study in two Canadian intensive care units (ICUs) from January…
View details →Beijer G, Swartling M, Nielsen EI et al. · 2025 · Critical care (London, England)
Background Standard dosing regimens of meropenem and piperacillin-tazobactam frequently fail to achieve targeted plasma concentrations in critically ill patients. Extended or continuous regimens are often used to improve target attainment.…
View details →Jang S, Kim D, Kim T et al. · 2025 · Nanotechnology
In this study, a Cleaning Endpoint Evaluation Sensor (CEES) was developed and applied to improve the monitoring accuracy and uniformity control in the cleaning processes for NF 3 -based remote plasma sources in semiconductor equipment.…
View details →Wang J · 2025 · Scandinavian journal of trauma, resuscitation and emergency medicine
This comment critiques a trial comparing intranasal dexmedetomidine (DEX) and esketamine (sKET) for pediatric procedural sedation. Despite a large effect size, the small sample (n = 29) likely caused false-negative results (p = 0.09),…
View details →Bacon EK, Parnell D, Muscatello G et al. · 2025 · Journal of equine veterinary science
Background The ongoing discussion surrounding the well-being of retired racehorses underscores the importance of implementing effective rehoming strategies that prioritise animal welfare. A significant knowledge gap persists regarding…
View details →Seidel M, Barns H, Klostermann C et al. · 2025 · Journal of Nutrition Education and Behavior
Nationwide, 41% - 48% of students on college campuses are food insecure (FI). These students are more likely to do poorly in school and drop out than their food secure (FS) peers. In 2017, 30% of students at Chatham University (CU), a…
View details →Lang A, Gabriel H, Meister TL et al. · 2026 · The Journal of hospital infection
Background Candida (Candidozyma) auris is a globally emerging multidrug-resistant fungal pathogen that causes nosocomial outbreaks in healthcare facilities. Aim To evaluate the susceptibility of different C. auris clade strains (I to V)…
View details →Felicioni F, Nivia-Riveros JA, Caldeira-Brant AL et al. · 2026 · The Journal of nutritional biochemistry
Proper fetal development depends on maternal nutrition. We investigated the placental morphofunctional adaptations to a low-protein diet, and their impact on fetal and newborn outcomes. Swiss mice were fed either normal (NPD, 20% crude…
View details →Boles B, Gardner JA, Rehder CW et al. · 2025 · Archives of pathology & laboratory medicine
Context.— The joint College of American Pathologists/American College of Medical Genetics and Genomics Cytogenetics Committee works to ensure competency and proficiency of clinical cytogenetics testing laboratories through proficiency…
View details →Tsuchie R, Hashimoto Y, Abiko M et al. · 2026 · Neurologia medico-chirurgica
Anatomical variations in the middle cerebral artery affect outcomes of mechanical thrombectomy in M1 occlusion cases. However, the relationship between middle cerebral artery branching patterns-specifically trifurcation and bifurcation-and…
View details →