12,375 real negative results, null findings, and replication failures in Medicine. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Markou M, Katsouda A, Papaioannou V et al. · 2024 · Phytotherapy research : PTR
Obesity is a major source of morbidity worldwide with more than 2 billion adults being overweight or obese. The incidence of obesity has tripled in the last 50 years, leading to an increased risk for a variety of noncommunicable diseases.…
View details →Carroll AM, Pruitt DT, Riley JR et al. · 2024 · Scientific reports
Learning new skills requires neuroplasticity. Vagus nerve stimulation (VNS) during sensory and motor events can increase neuroplasticity in networks related to these events and might therefore serve to facilitate learning on sensory and…
View details →Langley C, Plakotaris E, Rogers NE · 2025 · Case reports in dermatology
Introduction Lichen planopilaris (LPP) is a well-known cicatricial alopecia with a frontal fibrosing variant. LPP has a prevalence rate of 13.4 per 100,000 persons. It is understood that LPP favors the female populations. What is not…
View details →Panca M, Serfaty M, Satchell J et al. · 2026 · BJPsych open
Background Crime has significant impact on older victims. High rates of anxiety and depression may be associated with crimes. Aims This paper aims to evaluate the cost-effectiveness of a victim improvement package (VIP) for the reduction…
View details →Fernandes Cabral DT, Fernández-de Thomas RJ, Alattar A et al. · 2024 · Neurosurgical focus: Video
Odontoid pannus is an abnormal collection of degenerative or inflammatory tissue on the C1-dens joint that can result in severe spinal cord compression myelopathy. Treatment options vary depending on severity and etiology. In cases of…
View details →Story BD, Thomasy SM, Randolph MW et al. · 2024 · Frontiers in veterinary science
Sjogren's disease, well-described in people, is rarely identified in veterinary species. In people, Sjogren's disease is one of the most common systemic autoimmune disorders with an incidence of 0.5% in the female population. The hallmark…
View details →Sood M, Hegde V, Prabhu N et al. · 2026 · Journal of Indian Prosthodontic Society
Aim This study aimed to assess the shear bond strength between three-dimensional (3D)-printed acrylic denture base resin and 3D-printed teeth with and without ridge lap surface modifications. Materials and methods The investigation…
View details →Bhatia A, Chen Z, Zhang Y et al. · 2026 · Cancer
Background Ataxia telangiectasia Rad3-related (ATR) protein kinase regulates DNA damage response and is essential for tumor cell survival. Preclinically, ATR inhibition can sensitize tumor cells to radiation and chemotherapy. The authors…
View details →Gass R, Plachi F, Silva FOB et al. · 2025 · Respiratory physiology & neurobiology
Excess exercise ventilation (high ventilation (V̇ E )/carbon dioxide output (V̇CO 2 )) contributes significantly to dyspnea and exercise intolerance since the earlier stages of chronic obstructive pulmonary disease (COPD). A selective…
View details →Karajannis MA, Onar-Thomas A, Lin T et al. · 2025 · Neuro-oncology
Background The outcome for pediatric patients with high-grade glioma (HGG) remains poor. Veliparib, a potent oral poly(adenosine diphosphate-ribose) polymerase (PARP) 1/2 inhibitor, enhances the activity of radiotherapy and DNA-damaging…
View details →Pickard S, Speach D, Hauber K et al. · 2026 · Interventional pain medicine
Background Low back injury is one of the leading causes of work-related injuries, disability, and lost productivity. Patients with lumbar radiculopathy are a subgroup of patients within work related low back injury. To our knowledge, there…
View details →Luo JY, Xiang J, Hong XL et al. · 2026 · The American journal of case reports
BACKGROUND Epidermal growth factor receptor (EGFR) is a key driver gene in non-small-cell lung cancer (NSCLC), and EGFR tyrosine kinase inhibitors (TKIs) are the standard treatment for classical mutations, including exon 19 deletion and…
View details →Raj AK, Pedersen SJ, Mainsbridge C et al. · 2024 · Ergonomics
Prolonged sitting is postulated to influence musculoskeletal performance (cervical flexor endurance, balance, and agility), discomfort and alter cervical spine angles during work-based computer use. Stair climbing breaks may be a great…
View details →Li N, Wu C, Cao P et al. · 2024 · Access microbiology
Background Rhodococcus equi is one of the most important causes of zoonotic infections from grazing animals. It poses a particular risk to immunocompromised individuals, including those who are undergoing long-term immunosuppressive…
View details →Liu H, Hu Z, Song Q et al. · 2025 · JAMA network open
Importance Evidence from everyday dining situations regarding the effects of traffic light labels (TLLs) on dietary improvement remains inconsistent. Objective To evaluate the effects of TLLs on dietary consumption and choices in cafeteria…
View details →Awawdeh MS · 2024 · Journal of advanced veterinary and animal research
Objective The current study investigated the effects of supplying ruminally protected amino acids (AA) (lysine, L; and methionine, M) and dietary protein levels on the performance of late-nursing ewes. Materials and methods Thirty-one…
View details →Remaks JD, Vientos-Plotts AI, Rindt H et al. · 2024 · American journal of veterinary research
Objective To determine if multistrain probiotics administered to asthmatic cats treated with anti-inflammatory glucocorticoids would attenuate the asthmatic phenotype and beneficially alter respiratory, blood, and oropharyngeal (OP)…
View details →Cearns K, Lazarus ER, Wahid R · 2026 · The Canadian journal of nursing research = Revue canadienne de recherche en sciences infirmieres
BackgroundMental health nurses represent only 1.03% of the global nursing workforce, contributing to persistent workforce shortages. Undergraduate nursing students demonstrate limited interest in mental health nursing (MHN), often…
View details →S YK, Dwibedi B, Das RR · 2026 · European journal of pediatrics
Because of the excessive endogenous inflammatory mediators, acute encephalitis syndrome (AES) results in death, or sequelae in survivors. Pentoxifylline, a modulator of inflammation, can have beneficial role in AES. The primary objective…
View details →Ansaloni LS, Domingues CEC, Gregori M et al. · 2026 · Insects
Given the current global agricultural system, honey bees are exposed to a complex network of stressors that can act simultaneously, making it challenging to maintain healthy colonies. Therefore, studies on natural products to improve…
View details →Schmid SR, Blume C, Ell J et al. · 2026 · Journal of sleep research
Cognitive behavioural therapy for insomnia (CBT-I) is recommended as first-line treatment for insomnia disorder. However, around 25% of the patients do not respond to the treatment, and only 40% achieve full remission. The current study…
View details →Motta‐Romero HA, Guha S, Seravalli J et al. · 2024 · Cereal chemistry
BACKGROUND AND OBJECTIVES: Wheat porridge contributes to the intake of micronutrients but can also be a route of the toxic heavy metal, cadmium. This study aimed to determine the effect of processing on micronutrients, cadmium…
View details →Li W, Shi M, Zhou P et al. · 2024 · Pediatric blood & cancer
Background The outcome of extramedullary infiltration (EMI) in pediatric acute myeloid leukemia (AML) is controversial, and little is known about the implications of stem cell transplantation (SCT) and gemtuzumab ozogamicin (GO) treatment…
View details →Sun X, Yan T, Li Z et al. · 2023 · Nutrients
(1) Background: We investigated the effects of a 12-week exercise intervention with or without vitamin D supplementation on insulin resistance and the plasma lipidome of participants with type 2 diabetes. We further explored whether the…
View details →Liu X, Ma Y, Cui H et al. · 2026 · Frontiers in pediatrics
Background Extrauterine growth restriction (EUGR) critically impacts preterm infants, often due to nutritional deficiency. Lactational protein restriction can disrupt offspring glucose/lipid metabolism by altering gene expression and…
View details →Ward E, Hanbury G, Possamai L et al. · 2025 · BMJ open quality
Background End-stage liver disease (ESLD) is a terminal diagnosis with a poor prognosis and an accelerating mortality rate in the UK. Limited research suggests that patients with ESLD have unmet palliative care (PC) needs, likely due to…
View details →Akbarzadeh G, Abedi P, Jahanfar S et al. · 2024 · Frontiers in medicine
Background Sexual dysfunction is prevalent among breastfeeding women. Objective This study was designed to evaluate the effect of Rose damascene extract on sexual function and anxiety of breastfeeding women. Materials and methods This was…
View details →Nishiofuku H, Mori M, Yokomichi N et al. · 2024 · Journal of palliative medicine
Delirium is a distressing condition in terminally ill cancer patients, often treated with antipsychotics. Administering them orally, subcutaneously, or intravenously can be challenging in severely agitated patients. Transdermal…
View details →Oliver-Pons C, Sala-Vila A, Cofán M et al. · 2024 · Journal of the American Geriatrics Society
Background Nutritional strategies to maintain bone health in aging individuals are of great interest. Given the beneficial nutrient composition of walnuts, rich in alpha-linolenic (the vegetable n-3 fatty acid) and polyphenols, their…
View details →Wang Y, Wang C, Yin S et al. · 2025 · CNS neuroscience & therapeutics
Background Systemic therapeutic options for meningiomas remain limited. Emerging evidence indicates meningiomas harbor an immunosuppressive microenvironment and programmed cell death ligand 1 (PD-L1) expression is significantly upregulated…
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