Effects of sildenafil on gas exchange, ventilatory, and sensory responses to exercise in subjects with mild-to-moderate COPD: A randomized cross-over trial.
Gass R; Plachi F; Silva FOB; Nolasco T; Tonetto MS; Goelzer LS; Muller PT; Knorst MM · 2025 · Respiratory physiology & neurobiology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Excess exercise ventilation (high ventilation (V̇ E )/carbon dioxide output (V̇CO 2 )) contributes significantly to dyspnea and exercise intolerance since the earlier stages of chronic obstructive pulmonary disease (COPD). A selective…
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Metadata source: Europe PMC · DOI 10.1016/j.resp.2024.104359